Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy (Q36631660)

15 August 2017

1 reference

title

Mechanisms of disease: mitochondria as new therapeutic targets in diabetic neuropathy (English)

1 reference

15 August 2017

Eva L Feldman

1 reference

15 August 2017

Gina M Leinninger

1 reference

15 August 2017

James L Edwards

series ordinal

1 reference

15 August 2017

Matthew J Lipshaw

series ordinal

1 reference

15 August 2017

publication date

1 November 2006

1 reference

Nature Clinical Practice Neurology

15 August 2017

1 reference

inferred from page(s)

published in

1 reference

15 August 2017

1 reference

15 August 2017

1 reference

15 August 2017

page(s)

620-628

1 reference

Molecular understanding of hyperglycemia's adverse effects for diabetic complications

15 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Diabetic foot ulcers: a quality of life issue

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Incidence, outcomes, and cost of foot ulcers in patients with diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Reactive, degenerative, and proliferative Schwann cell responses in experimental galactose and human diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Pathology and time relationship of peripheral nerve changes in experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Complications: neuropathy, pathogenetic considerations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Oxidative injury and apoptosis of dorsal root ganglion neurons in chronic experimental diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Sural nerve morphometry in diabetic autonomic and painful sensory neuropathy. A clinicopathological study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Biochemistry and molecular cell biology of diabetic complications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Expression of Mfn2, the Charcot-Marie-Tooth neuropathy type 2A gene, in human skeletal muscle: effects of type 2 diabetes, obesity, weight loss, and the regulatory role of tumor necrosis factor alpha and interleukin-6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

High glucose-induced oxidative stress and mitochondrial dysfunction in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Cell culture modeling to test therapies against hyperglycemia-mediated oxidative stress and injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Insulin-like growth factor-I regulates glucose-induced mitochondrial depolarization and apoptosis in human neuroblastoma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mitochondrial DNA content is decreased in autosomal dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Antioxidants modulate mitochondrial PKA and increase CREB binding to D-loop DNA of the mitochondrial genome in neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Regulation of mitochondrial gene expression by energy demand in neural cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Recent advances in drug-induced neuropathies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Axonal self-destruction and neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Glucose-induced oxidative stress and programmed cell death in diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Neurons undergo apoptosis in animal and cell culture models of diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Sensory neurons with activated caspase-3 survive long-term experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Diabetic peripheral neuropathy: evidence for apoptosis and associated mitochondrial dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Does diabetes target ganglion neurones? Progressive sensory neurone involvement in long-term experimental diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Apoptosis in the developing visual system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Bcl-2 family gene products in cerebral ischemia and traumatic brain injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Identification of novel isoforms of the BH3 domain protein Bim which directly activate Bax to trigger apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mitochondrial membrane permeabilisation by Bax/Bak

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Bax oligomerization is required for channel-forming activity in liposomes and to trigger cytochrome c release from mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Hydrogen peroxide-mediated cytosolic acidification is a signal for mitochondrial translocation of Bax during drug-induced apoptosis of tumor cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mitochondrial morphology is dynamic and varied

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Dynamics of mitochondrial morphology in healthy cells and during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mutations in the mitochondrial GTPase mitofusin 2 cause Charcot-Marie-Tooth neuropathy type 2A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Roles of the mammalian mitochondrial fission and fusion mediators Fis1, Drp1, and Opa1 in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Spatial and temporal association of Bax with mitochondrial fission sites, Drp1, and Mfn2 during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Establishment of Stable hFis1 Knockdown Cells with an siRNA Expression Vector

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Increased production of reactive oxygen species in hyperglycemic conditions requires dynamic change of mitochondrial morphology

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Sorbitol and myo-inositol levels and morphology of sural nerve in relation to peripheral nerve function and clinical neuropathy in men with diabetic, impaired, and normal glucose tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Direct insulin signaling of neurons reverses diabetic neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Insulin prevents depolarization of the mitochondrial inner membrane in sensory neurons of type 1 diabetic rats in the presence of sustained hyperglycemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Poly(ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

Mitochondria: pharmacological manipulation of cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

The continuing epidemics of obesity and diabetes in the United States

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

7 January 2021

Short-term hyperglycemia produces oxidative damage and apoptosis in neurons

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

7 January 2021

Phosphatidylinositol 3-kinase and Akt effectors mediate insulin-like growth factor-I neuroprotection in dorsal root ganglia neurons.

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

7 January 2021

Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1

1 reference

https://api.crossref.org/works/10.1038%2FNCPNEURO0320

7 January 2021

Identifiers

DOI

10.1038/NCPNEURO0320

1 reference

Dimensions Publication ID

15 August 2017

1006792979

0 references

1 reference