Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer. (Q36617328)

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5 February 2020

title

Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer (English)

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5 February 2020

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5 February 2020

Lauren J Bayne

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5 February 2020

Nirag Jhala

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5 February 2020

Carolyn E Clark

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5 February 2020

Andrew D Rhim

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5 February 2020

Ben Z Stanger

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5 February 2020

Robert H Vonderheide

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5 February 2020

publication date

1 June 2012

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5 February 2020

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5 February 2020

volume

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5 February 2020

issue

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5 February 2020

page(s)

822-835

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Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia

5 February 2020

cites work

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Deletion of p120-Catenin Results in a Tumor Microenvironment with Inflammation and Cancer that Establishes It as a Tumor Suppressor Gene

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30 September 2017

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30 September 2017

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Hierarchy of immunosuppressive strength among myeloid-derived suppressor cell subsets is determined by GM-CSF.

30 September 2017

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GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

30 September 2017

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Cytokine levels correlate with immune cell infiltration after anti-VEGF therapy in preclinical mouse models of breast cancer

30 September 2017

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MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines

30 September 2017

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Myeloid-derived suppressor cells: linking inflammation and cancer

30 September 2017

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Myeloid-derived suppressor cells as regulators of the immune system

30 September 2017

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Immunosurveillance of pancreatic adenocarcinoma: insights from genetically engineered mouse models of cancer.

30 September 2017

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Overexpression of interleukin-1beta induces gastric inflammation and cancer and mobilizes myeloid-derived suppressor cells in mice.

30 September 2017

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Overexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis

30 September 2017

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Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis

30 September 2017

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Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression

30 September 2017

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Distinct roles of VEGFR-1 and VEGFR-2 in the aberrant hematopoiesis associated with elevated levels of VEGF.

30 September 2017

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Cooperative induction of a tolerogenic dendritic cell phenotype by cytokines secreted by pancreatic carcinoma cells

30 September 2017

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Inflammation induces myeloid-derived suppressor cells that facilitate tumor progression

30 September 2017

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30 September 2017

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Role of immature myeloid cells in mechanisms of immune evasion in cancer

30 September 2017

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Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

30 September 2017

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30 September 2017

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High-dose granulocyte-macrophage colony-stimulating factor-producing vaccines impair the immune response through the recruitment of myeloid suppressor cells

30 September 2017

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30 September 2017

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30 September 2017

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Unopposed production of granulocyte-macrophage colony-stimulating factor by tumors inhibits CD8+ T cell responses by dysregulating antigen-presenting cell maturation.

30 September 2017

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Histamine deficiency promotes inflammation-associated carcinogenesis through reduced myeloid maturation and accumulation of CD11b+Ly6G+ immature myeloid cells

30 September 2017

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The terminology issue for myeloid-derived suppressor cells

28 June 2018

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Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity

28 June 2018

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IL-4-induced arginase 1 suppresses alloreactive T cells in tumor-bearing mice

20 September 2018

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Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer

20 September 2018

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12 December 2020

Dynamics of the immune reaction to pancreatic cancer from inception to invasion

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12 December 2020

Sensitive and viable identification of antigen-specific CD8+ T cells by a flow cytometric assay for degranulation

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12 December 2020

Expansion of myeloid immune suppressor Gr+CD11b+ cells in tumor-bearing host directly promotes tumor angiogenesis

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12 December 2020

Vascular endothelial growth factor inhibits the development of dendritic cells and dramatically affects the differentiation of multiple hematopoietic lineages in vivo

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12 December 2020

CD11b+/Gr-1+ immature myeloid cells mediate suppression of T cells in mice bearing tumors of IL-1beta-secreting cells

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12 December 2020

10.1016/J.CCR.2012.04.025

Identifiers

DOI

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5 February 2020

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5 February 2020

PubMed publication ID

22698406

1 reference

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