Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding. (Q36483449)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160719%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Protein kinase A-dependent phosphorylation modulates beta1Pix guanine nucleotide exchange factor activity through 14-3-3beta binding (English)

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31 December 2019

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31 December 2019

Ahmed Chahdi

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31 December 2019

language of work or name

English

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publication date

26 December 2007

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Molecular and Cellular Biology

31 December 2019

published in

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volume

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issue

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31 December 2019

page(s)

1679-1687

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Paxillin phosphorylation at Ser273 localizes a GIT1-PIX-PAK complex and regulates adhesion and protrusion dynamics

31 December 2019

cites work

1 reference

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Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix

30 September 2017

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Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration

30 September 2017

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A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC

30 September 2017

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Leucine zipper-mediated homo-oligomerization regulates the Rho-GEF activity of AKAP-Lbc

30 September 2017

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Endothelin 1 induces beta 1Pix translocation and Cdc42 activation via protein kinase A-dependent pathway.

30 September 2017

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Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization

30 September 2017

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Novel regulatory mechanisms for the Dbl family guanine nucleotide exchange factor Cool-2/alpha-Pix

30 September 2017

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Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex

30 September 2017

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Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2.

30 September 2017

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p21-activated kinase 1 phosphorylates and regulates 14-3-3 binding to GEF-H1, a microtubule-localized Rho exchange factor

30 September 2017

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Homo- and hetero-oligomerization of PDZ-RhoGEF, LARG and p115RhoGEF by their C-terminal region regulates their in vivo Rho GEF activity and transforming potential

30 September 2017

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Significance of 14-3-3 self-dimerization for phosphorylation-dependent target binding

30 September 2017

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14-3-3s regulate fructose-2,6-bisphosphate levels by binding to PKB-phosphorylated cardiac fructose-2,6-bisphosphate kinase/phosphatase

30 September 2017

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How do 14-3-3 proteins work?-- Gatekeeper phosphorylation and the molecular anvil hypothesis

30 September 2017

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GIT1 functions in a motile, multi-molecular signaling complex that regulates protrusive activity and cell migration

30 September 2017

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14-3-3 inhibits Bad-induced cell death through interaction with serine-136

30 September 2017

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14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation

30 September 2017

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Identification of a novel interaction of 14-3-3 with p190RhoGEF.

30 September 2017

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14-3-3 proteins: structure, function, and regulation

30 September 2017

1 reference

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Interaction between PAK and nck: a template for Nck targets and role of PAK autophosphorylation

30 September 2017

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A tyrosine-phosphorylated protein that binds to an important regulatory region on the cool family of p21-activated kinase-binding proteins

30 September 2017

1 reference

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Paxillin LD4 motif binds PAK and PIX through a novel 95-kD ankyrin repeat, ARF-GAP protein: A role in cytoskeletal remodeling

30 September 2017

1 reference

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A novel regulator of p21-activated kinases

30 September 2017

1 reference

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14-3-3 proteins are required for maintenance of Raf-1 phosphorylation and kinase activity

30 September 2017

1 reference

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PAK kinases are directly coupled to the PIX family of nucleotide exchange factors

30 September 2017

1 reference

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The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity

30 September 2017

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Raf-1 kinase and exoenzyme S interact with 14-3-3zeta through a common site involving lysine 49.

30 September 2017

1 reference

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Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein Ib alpha

30 September 2017

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14-3-3-affinity purification of over 200 human phosphoproteins reveals new links to regulation of cellular metabolism, proliferation and trafficking

30 September 2017

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Beta1PIX, the PAK-interacting exchange factor, requires localization via a coiled-coil region to promote microvillus-like structures and membrane ruffles

28 June 2018

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Leucine zipper-mediated homodimerization of the p21-activated kinase-interacting factor, beta Pix. Implication for a role in cytoskeletal reorganization

28 June 2018

1 reference

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betaPak-interacting exchange factor-mediated Rac1 activation requires smgGDS guanine nucleotide exchange factor in basic fibroblast growth factor-induced neurite outgrowth

28 June 2018

1 reference

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Cdc42 controls the polarity of the actin and microtubule cytoskeletons through two distinct signal transduction pathways.

21 September 2018

1 reference

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14-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta

21 September 2018

1 reference

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Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258773

14-3-3 epsilon positively regulates Ras-mediated signaling in Drosophila

21 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2258773

21 September 2018

Identifiers

DOI

10.1128/MCB.00898-07

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160719%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

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31 December 2019

PubMed publication ID

18160719

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18160719%20AND%20SRC:MED&resulttype=core&format=json