The role of phenotype in gene discovery in the whole genome sequencing era. (Q36475964)

14 August 2017

The role of phenotype in gene discovery in the whole genome sequencing era. (English)

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14 August 2017

whole genome sequencing

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1 reference

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Laura Almasy

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14 August 2017

22 June 2012

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14 August 2017

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14 August 2017

131

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14 August 2017

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14 August 2017

1533-1540

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Identification of common variants associated with human hippocampal and intracranial volumes

14 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Identifying rare variants from exome scans: the GAW17 experience

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

High dimensional endophenotype ranking in the search for major depression risk genes

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

The use of phenome-wide association studies (PheWAS) for exploration of novel genotype-phenotype relationships and pleiotropy discovery

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Bivariate association analysis in selected samples: application to a GWAS of two bone mineral density phenotypes in males with high or low BMD.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Ordered subset analysis for case-control studies

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genome-wide association study of recurrent early-onset major depressive disorder

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genome-wide association study for empirically derived metabolic phenotypes in the Framingham Heart Study offspring cohort

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genetic Analysis Workshop 16: Strategies for genome-wide association study analyses

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Common disorders are quantitative traits

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Ordered-subset analysis (OSA) for family-based association mapping of complex traits

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genomewide linkage scan for opioid dependence and related traits

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Genetic Analysis Workshop 14: microsatellite and single-nucleotide polymorphism marker loci for genome-wide scans

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Novel family-based approaches to genetic risk in thrombosis

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

The endophenotype concept in psychiatry: etymology and strategic intentions

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

The genetic defect causing familial Alzheimer's disease maps on chromosome 21.

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Linkage of early-onset familial breast cancer to chromosome 17q21

28 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3525519

Factors of insulin resistance syndrome--related phenotypes are linked to genetic locations on chromosomes 6 and 7 in nondiabetic mexican-americans

28 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-012-1191-1

Suggestive linkage on chromosome 1 for a quantitative alcohol-related phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-012-1191-1

On multiple-testing correction in genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-012-1191-1

Common disorders are quantitative traits

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00439-012-1191-1

Bivariate quantitative trait linkage analysis: Pleiotropy versus co-incident linkages

21 January 2018

1 reference

12 December 2020

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

1 reference

12 December 2020

A principal-components approach based on heritability for combining phenotype information

1 reference

12 December 2020

Comparison of Multivariate Tests for Genetic Linkage

1 reference

12 December 2020

10.1007/S00439-012-1191-1

Identifiers

DOI

1 reference

14 August 2017

1 reference

PMC publication ID

3525519

14 August 2017

PubMed publication ID

22722752

1 reference

PMC publication ID

3525519