Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer (Q36453905)

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English	Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

review article

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Europe PubMed Central

title

Expression of activated oncogenes in the murine mammary gland: transgenic models for human breast cancer (English)

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Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

author name string

Muller WJ

series ordinal

1

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stated in

Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

publication date

1 October 1991

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Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

published in

Cancer and Metastasis Reviews

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Europe PubMed Central

PubMed publication ID

1662559

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14 August 2017

volume

10

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stated in

Europe PubMed Central

PubMed publication ID

1662559

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14 August 2017

issue

3

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Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

page(s)

217-227

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Europe PubMed Central

PubMed publication ID

1662559

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14 August 2017

cites work

Requirement for the simian virus 40 small tumor antigen in tumorigenesis in transgenic mice

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The roles of individual polyoma virus early proteins in oncogenic transformation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

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Potential oncogene product related to growth factors

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic alteration of the c-myc protooncogene (MYC) in human primary breast carcinomas

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequence, topography and protein coding potential of mouse int-2: a putative oncogene activated by mouse mammary tumour virus

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of c-erbB-2 oncogene in human adenocarcinomas in vivo

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Animal models of human disease. Pathology and molecular biology of spontaneous neoplasms occurring in transgenic mice carrying and expressing activated cellular oncogenes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

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Tumorigenesis and male sterility in transgenic mice expressing a MMTV/N-ras oncogene

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The int-2 gene product acts as an epithelial growth factor in transgenic mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

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Oncogenicity of the ret transforming gene in MMTV/ret transgenic mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct mutagenesis of Ha-ras-1 oncogenes by N-nitroso-N-methylurea during initiation of mammary carcinogenesis in rats.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of a variety of tumors by c-erbB2 and clonal nature of lymphomas even with the mutated gene (Val659----Glu659).

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ha-ras oncogene expression directed by a milk protein gene promoter: tissue specificity, hormonal regulation, and tumor induction in transgenic mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human basic fibroblast growth factor: nucleotide sequence and genomic organization

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new nomenclature for int-1 and related genes: the Wnt gene family

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice carrying the mouse mammary tumor virus ras fusion gene: distinct effects in various tissues

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A human immunoglobulin gene reduces the incidence of lymphomas in c-Myc-bearing transgenic mice.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural rearrangement of the retinoblastoma gene in human breast carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stochastic appearance of mammary tumors in transgenic mice carrying the MMTV/c-neu oncogene

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the proto-oncogene int-1 is restricted to postmeiotic male germ cells and the neural tube of mid-gestational embryos.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cooperation between oncogenes

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stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of a rearranged human transforming gene following transfection of Kaposi sarcoma DNA.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure and nucleotide sequence of the putative mammary oncogene int-1; proviral insertions leave the protein-encoding domain intact

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the retinoblastoma susceptibility gene in human breast cancers

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HER-2/neu amplification predicts poor survival in node-positive breast cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An immunohistochemical evaluation of c-erbB-2 expression in human breast carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ c-myc expression and genomic status of the c-myc locus in infiltrating ductal carcinomas of the breast

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of human int-2 in breast cancers and squamous carcinomas

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted c-myc gene expression in mammary glands of transgenic mice induces mammary tumours with constitutive milk protein gene transcription

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ha-ras and c-myc oncogene expression interferes with morphological and functional differentiation of mammary epithelial cells in single and double transgenic mice

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple regulatory domains in the mouse mammary tumor virus long terminal repeat revealed by analysis of fusion genes in transgenic mice

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations to either c-erbB-2(neu) or c-myc proto-oncogenes in breast carcinomas correlate with poor short-term prognosis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of c-erbB-2 and aggressive human breast tumors?

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the int-1 gene in transgenic mice is associated with mammary gland hyperplasia and adenocarcinomas in male and female mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A retrovirus vector expressing the putative mammary oncogene int-1 causes partial transformation of a mammary epithelial cell line

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of TGFα in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice as probes into complex systems

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Transforming Growth Factor α (TGFα) in Differentiated Rat Mammary Tumors: Estrogen Induction of TGFα Production

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amplification of a novel v-erbB-related gene in a human mammary carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal development

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binary system for regulating transgene expression in mice: targeting int-2 gene expression with yeast GAL4/UAS control elements.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Spontaneous mammary adenocarcinomas in transgenic mice that carry and express MTV/myc fusion genes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Germ-line transmission of a mutated p53 gene in a cancer-prone family with Li-Fraumeni syndrome

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexpression of MMTV/v-Ha-ras and MMTV/c-myc genes in transgenic mice: synergistic action of oncogenes in vivo

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor alpha production and epidermal growth factor receptor expression in normal and oncogene transformed human mammary epithelial cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice bearing the E mu-myc and E mu-pim-1 transgenes develop pre-B-cell leukemia prenatally

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mouse model for human gastric carcinoma

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Predisposition to lymphomagenesis in pim-1 transgenic mice: cooperation with c-myc and N-myc in murine leukemia virus-induced tumors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The int genes in mammary tumorigenesis and in normal development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/1662559

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1007/BF00050793

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

PubMed publication ID

1662559

1 reference

stated in

Europe PubMed Central

PubMed publication ID

1662559

retrieved

14 August 2017

 

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