On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sieving (Q36436032)

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English	On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sieving	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

14 August 2017

On the structural basis for size-selective permeation of organic cations through the voltage-gated sodium channel. Effect of alanine mutations at the DEKA locus on selectivity, inhibition by Ca2+ and H+, and molecular sieving (English)

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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author name string

Y M Sun

1

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Europe PubMed Central

PMC publication ID

14 August 2017

I Favre

2

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Europe PubMed Central

PMC publication ID

14 August 2017

L Schild

3

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Europe PubMed Central

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14 August 2017

E Moczydlowski

4

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Europe PubMed Central

PMC publication ID

14 August 2017

publication date

1 December 1997

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Europe PubMed Central

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14 August 2017

The Journal of General Physiology

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Europe PubMed Central

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14 August 2017

110

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Europe PubMed Central

PMC publication ID

14 August 2017

6

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Europe PubMed Central

PMC publication ID

14 August 2017

693-715

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Europe PubMed Central

PMC publication ID

14 August 2017

Altered ionic selectivity of the sodium channel revealed by cysteine mutations within the pore

1 reference

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On the structural basis for ionic selectivity among Na+, K+, and Ca2+ in the voltage-gated sodium channel

1 reference

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Molecular basis of proton block of L-type Ca2+ channels

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1 reference

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A mu-conotoxin-insensitive Na+ channel mutant: possible localization of a binding site at the outer vestibule

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Specificity for block by saxitoxin and divalent cations at a residue which determines sensitivity of sodium channel subtypes to guanidinium toxins

1 reference

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Molecular localization of ion selectivity sites within the pore of a human L-type cardiac calcium channel

1 reference

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Molecular pore structure of voltage-gated sodium and calcium channels.

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Structural basis of ion channel permeation and selectivity

1 reference

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Permeability properties of chick myotube acetylcholine-activated channels

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Voltage-dependent calcium block of normal and tetramethrin-modified single sodium channels

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The permeability of the endplate channel to organic cations in frog muscle

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Ionic selectivity revisited: The role of kinetic and equilibrium processes in ion permeation through channels

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The permeability of the sodium channel to metal cations in myelinated nerve

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Negative Conductance Caused by Entry of Sodium and Cesium Ions into the Potassium Channels of Squid Axons

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Ionic Blockage of Sodium Channels in Nerve

1 reference

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Potassium channels in myelinated nerve. Selective permeability to small cations

1 reference

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High-efficiency transformation of mammalian cells by plasmid DNA

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Effects of membrane surface charge and calcium on the gating of rat brain sodium channels in planar bilayers

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30 September 2017

Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating properties

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30 September 2017

Calcium block of guinea-pig heart sodium channels with and without modification by the piperazinylindole DPI 201-106.

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An introduction to molecular architecture and permeability of ion channels

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Monovalent ion current through single calcium channels of skeletal muscle transverse tubules

1 reference

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The Ca channel in skeletal muscle is a large pore

1 reference

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Divalent cation selectivity for external block of voltage-dependent Na+ channels prolonged by batrachotoxin. Zn2+ induces discrete substates in cardiac Na+ channels

1 reference

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Zn2(+)-induced subconductance events in cardiac Na+ channels prolonged by batrachotoxin. Current-voltage behavior and single-channel kinetics

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Calcium ion as a cofactor in Na channel gating

1 reference

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Tris+/Na+ permeability ratios of nicotinic acetylcholine receptors are reduced by mutations near the intracellular end of the M2 region

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Access resistance and space clamp problems associated with whole-cell patch clamping

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Ionic selectivity of the sodium channel of frog skeletal muscle

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Kinetic and pharmacological properties of the sodium channel of frog skeletal muscle

1 reference

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Pore properties of rat brain II sodium channels mutated in the selectivity filter domain

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Proton block of rat brain sodium channels. Evidence for two proton binding sites and multiple occupancy

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Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229404

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Ca2+ channel selectivity at a single locus for high-affinity Ca2+ interactions

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Mechanism of ion permeation through calcium channels

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Non-selective conductance in calcium channels of frog muscle: calcium selectivity in a single-file pore

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Prediction of electrostatic effects of engineering of protein charges.

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Primary structure and functional expression of a mammalian skeletal muscle sodium channel

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Effects of external protons on single cardiac sodium channels from guinea pig ventricular myocytes

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229404

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Mapping the site of block by tetrodotoxin and saxitoxin of sodium channel II.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229404

28 June 2018

Action of derivatives of mu-conotoxin GIIIA on sodium channels. Single amino acid substitutions in the toxin separately affect association and dissociation rates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229404

28 June 2018

Calcium channel characteristics conferred on the sodium channel by single mutations

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28 June 2018

The action of calcium on the electrical properties of squid axons.

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Characterizing the mu-conotoxin binding site on voltage-sensitive sodium channels with toxin analogs and channel mutations.

1 reference

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21 September 2018

Structural determinants of ion selectivity in brain calcium channel

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Role of H5 domain in determining pore diameter and ion permeation through cyclic nucleotide-gated channels

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21 September 2018

Voltage-clamp experiments in normal and denervated mammalian skeletal muscle fibres

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21 September 2018

The permeability of the sodium channel to organic cations in myelinated nerve

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2229404

21 September 2018

Active site of mu-conotoxin GIIIA, a peptide blocker of muscle sodium channels

1 reference

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12 December 2020

based on heuristic

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Cysteine mapping in the ion selectivity and toxin binding region of the cardiac Na+ channel pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tertiary structure of conotoxin GIIIA in aqueous solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for existence of two acid groups controlling the conductance of sodium channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A non-selective cation conductance in frog muscle membrane blocked by micromolar external calcium ions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pore size and negative charge as structural determinants of permeability in the Torpedo nicotinic acetylcholine receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depth asymmetries of the pore-lining segments of the Na+ channel revealed by cysteine mutagenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ion permeation through the L-type Ca2+ channel in rat phaeochromocytoma cells: two sets of ion binding sites in the pore

1 reference

https://pubmed.ncbi.nlm.nih.gov/9382897

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1085/JGP.110.6.693

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

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