Drosophila models pioneer a new approach to drug discovery for Parkinson's disease (Q36419985)

14 August 2017

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title

Drosophila models pioneer a new approach to drug discovery for Parkinson's disease (English)

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14 August 2017

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Paul D Wes

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Alexander J. Whitworth

object named as

Alexander J Whitworth

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Leo J Pallanck

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14 August 2017

publication date

1 February 2006

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14 August 2017

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14 August 2017

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14 August 2017

issue

3-4

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14 August 2017

page(s)

119-126

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Molecular pathogenesis of Parkinson disease

14 August 2017

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Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease

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Parkin suppresses dopaminergic neuron-selective neurotoxicity induced by Pael-R in Drosophila

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Parkin counteracts symptoms in a Drosophila model of Parkinson's disease

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alpha-Synuclein is phosphorylated in synucleinopathy lesions

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Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein

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Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila

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Alpha-synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease

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Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells.

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Whole-mount analysis reveals normal numbers of dopaminergic neurons following misexpression of alpha-Synuclein in Drosophila

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Effects of pharmacological agents upon a transgenic model of Parkinson's disease in Drosophila melanogaster

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Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress

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Parkin negatively regulates JNK pathway in the dopaminergic neurons of Drosophila

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Increased glutathione S-transferase activity rescues dopaminergic neuron loss in a Drosophila model of Parkinson's disease

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7 January 2021

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Genetic and genomic studies of Drosophila parkin mutants implicate oxidative stress and innate immune responses in pathogenesis.

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7 January 2021

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7 January 2021

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Identifiers

DOI

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14 August 2017

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