Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17beta-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats (Q36409841)

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English	Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17beta-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats	scientific article

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scholarly article

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PMC publication ID

14 August 2017

Gene expression profiling identifies lobe-specific and common disruptions of multiple gene networks in testosterone-supported, 17beta-estradiol- or diethylstilbestrol-induced prostate dysplasia in Noble rats (English)

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Europe PubMed Central

PMC publication ID

14 August 2017

3

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Maureen A Sartor

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Europe PubMed Central

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14 August 2017

author name string

Neville N C Tam

1

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14 August 2017

Carol Ying-Ying Szeto

2

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14 August 2017

Mario Medvedovic

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14 August 2017

Shuk-Mei Ho

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14 August 2017

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1 January 2008

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14 August 2017

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Europe PubMed Central

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14 August 2017

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Europe PubMed Central

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14 August 2017

1

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14 August 2017

20-40

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14 August 2017

describes a project that uses

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Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/2216049

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Sex hormones induce direct epithelial and inflammation-mediated oxidative/nitrosative stress that favors prostatic carcinogenesis in the noble rat.

1 reference

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Genetic ablation of CCAAT/enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis

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Cancer risk in women prenatally exposed to diethylstilbestrol

1 reference

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30 September 2017

Estrogens and mechanisms of prostate cancer progression.

1 reference

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30 September 2017

Estrogens and antiestrogens as etiological factors and therapeutics for prostate cancer.

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A conditionally immortalized cell line model for the study of human prostatic epithelial cell differentiation

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Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling.

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Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments

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Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes

1 reference

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Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4

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Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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Aromatase and prostate cancer.

1 reference

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Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.

1 reference

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Interaction between Smad7 and beta-catenin: importance for transforming growth factor beta-induced apoptosis

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Loss of HOXC6 expression induces apoptosis in prostate cancer cells

1 reference

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Gene expression profiling identifies a unique androgen-mediated inflammatory/immune signature and a PTEN (phosphatase and tensin homolog deleted on chromosome 10)-mediated apoptotic response specific to the rat ventral prostate

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Dynamic regulation of estrogen receptor-beta expression by DNA methylation during prostate cancer development and metastasis

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Microarray results improve significantly as hybridization approaches equilibrium.

1 reference

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Aberrant HOXC expression accompanies the malignant phenotype in human prostate

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Alterations of p53 are common in early stage prostate cancer

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Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase kinase 3

1 reference

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Xenoestrogen exposure and mechanisms of endocrine disruption

1 reference

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30 September 2017

Gene expression profiling of testosterone and estradiol-17 beta-induced prostatic dysplasia in Noble rats and response to the antiestrogen ICI 182,780

1 reference

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1 reference

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Overexpression of the homeobox gene HOXC8 in human prostate cancer correlates with loss of tumor differentiation

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p53 Alteration and chromosomal instability in prostatic high-grade intraepithelial neoplasia and concurrent carcinoma: analysis by immunohistochemistry, interphase in situ hybridization, and sequencing of laser-captured microdissected specimens.

1 reference

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Clinical review 134: The endocrinology of prostate cancer

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Comparative studies of the estrogen receptors beta and alpha and the androgen receptor in normal human prostate glands, dysplasia, and in primary and metastatic carcinoma

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Cancer risk in men exposed in utero to diethylstilbestrol

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Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation

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Induction at high incidence of ductal prostate adenocarcinomas in NBL/Cr and Sprague-Dawley Hsd:SD rats treated with a combination of testosterone and estradiol-17 beta or diethylstilbestrol.

1 reference

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Biochemical alterations in sex hormone-induced hyperplasia and dysplasia of the dorsolateral prostates of Noble rats

1 reference

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Sex steroids and prostate carcinogenesis: integrated, multifactorial working hypothesis

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Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis

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17beta-estradiol-induced activation of ERK1/2 through endogenous androgen receptor-estradiol receptor alpha-Src complex in human prostate cells.

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21 September 2018

Sex hormone-induced alterations in the activities of antioxidant enzymes and lipid peroxidation status in the prostate of Noble rats

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21 September 2018

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21 September 2018

Differential effects of diethylstilbestrol and estradiol-17 beta in combination with testosterone on rat prostate lobes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18231636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Androgen-supported estrogen-enhanced epithelial proliferation in the prostates of intact Noble rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/18231636

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1593/NEO.07889

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

14 August 2017

ResearchGate publication ID

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