Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model (Q36351079)

13 August 2017

Metabolic remodeling agents show beneficial effects in the dystrophin-deficient mdx mouse model (English)

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13 August 2017

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Kanneboyina Nagaraju

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13 August 2017

Eric P Hoffman

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13 August 2017

Vanessa E Jahnke

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13 August 2017

Jack H Van Der Meulen

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13 August 2017

Helen K Johnston

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13 August 2017

Svetlana Ghimbovschi

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13 August 2017

Terrence Partridge

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13 August 2017

21 August 2012

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13 August 2017

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13 August 2017

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13 August 2017

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13 August 2017

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describes a project that uses

13 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3482394/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Rescue of dystrophic skeletal muscle by PGC-1α involves a fast to slow fiber type shift in the mdx mouse

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PPARδ regulates satellite cell proliferation and skeletal muscle regeneration

30 September 2017

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Chronic AMPK activation evokes the slow, oxidative myogenic program and triggers beneficial adaptations in mdx mouse skeletal muscle

30 September 2017

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Daily treatment with SMTC1100, a novel small molecule utrophin upregulator, dramatically reduces the dystrophic symptoms in the mdx mouse

30 September 2017

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miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy

30 September 2017

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Peroxisome proliferator-activated receptor gamma coactivator 1alpha or 1beta overexpression inhibits muscle protein degradation, induction of ubiquitin ligases, and disuse atrophy

30 September 2017

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Mitochondrial fission and remodelling contributes to muscle atrophy.

30 September 2017

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Activation of peroxisome proliferator-activated receptor-{delta} by GW501516 prevents fatty acid-induced nuclear factor-{kappa}B activation and insulin resistance in skeletal muscle cells

30 September 2017

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Evidence for mitochondrial respiratory deficiency in rat rhabdomyosarcoma cells

30 September 2017

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Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

30 September 2017

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Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

30 September 2017

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Pharmacological activation of PPARbeta/delta stimulates utrophin A expression in skeletal muscle fibers and restores sarcolemmal integrity in mature mdx mice

30 September 2017

1 reference

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Preclinical drug trials in the mdx mouse: assessment of reliable and sensitive outcome measures

30 September 2017

1 reference

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AMPK and PPARdelta agonists are exercise mimetics

30 September 2017

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Signaling in muscle atrophy and hypertrophy

30 September 2017

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The role of mitochondria in aging of skeletal muscle

30 September 2017

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Energy sensing and regulation of gene expression in skeletal muscle

30 September 2017

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PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

30 September 2017

1 reference

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Activation of PPAR-delta in isolated rat skeletal muscle switches fuel preference from glucose to fatty acids

30 September 2017

1 reference

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Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors

30 September 2017

1 reference

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Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

30 September 2017

1 reference

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Molecular pathways leading to cancer cachexia

30 September 2017

1 reference

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Regulation of muscle fiber type and running endurance by PPARdelta

30 September 2017

1 reference

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

30 September 2017

1 reference

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Activation of peroxisome proliferator-activated receptor delta induces fatty acid beta-oxidation in skeletal muscle and attenuates metabolic syndrome

30 September 2017

1 reference

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The peroxisome proliferator-activated receptor beta/delta agonist, GW501516, regulates the expression of genes involved in lipid catabolism and energy uncoupling in skeletal muscle cells

30 September 2017

1 reference

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Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.

30 September 2017

1 reference

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Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

30 September 2017

1 reference

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The role of utrophin in the potential therapy of Duchenne muscular dystrophy

30 September 2017

1 reference

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Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

30 September 2017

1 reference

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Function and genetics of dystrophin and dystrophin-related proteins in muscle

30 September 2017

1 reference

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Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle

30 September 2017

1 reference

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Expression of full-length utrophin prevents muscular dystrophy in mdx mice

30 September 2017

1 reference

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Contractile properties of skeletal muscles from young, adult and aged mice

30 September 2017

1 reference

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Defective regulation of energy metabolism in mdx-mouse skeletal muscles

30 September 2017

1 reference

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Quantitative proteomic analysis of dystrophic dog muscle.

29 June 2018

1 reference

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Mutation in dystrophin-encoding gene affects energy metabolism in mouse myoblasts

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482394

Control of mitochondrial biogenesis, ROS level, and cytosolic Ca2+ concentration during the cell cycle and the onset of differentiation in L6E9 myoblasts

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482394

Peroxisome proliferator-activated receptor-gamma co-activator 1alpha-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482394

Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482394

Mechanical stress activates the nuclear factor-kappaB pathway in skeletal muscle fibers: a possible role in Duchenne muscular dystrophy.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3482394

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

22 September 2018

1 reference

12 December 2020

Persistent over-expression of specific CC class chemokines correlates with macrophage and T-cell recruitment in mdx skeletal muscle

1 reference

12 December 2020

Role of AMP kinase and PPARdelta in the regulation of lipid and glucose metabolism in human skeletal muscle.

1 reference

12 December 2020

Autophagy induction rescues muscular dystrophy

1 reference

12 December 2020

Identifiers

DOI

10.1186/2044-5040-2-16

1 reference

Dimensions Publication ID

13 August 2017

0 references

1 reference

13 August 2017

PubMed publication ID

22908954

1 reference