Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand (Q36334890)

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English	Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Geldanamycin induces apoptosis in human gastric carcinomas by affecting multiple oncogenic kinases that have synergic effects with TNF-related apoptosis-inducing ligand (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

apoptotic process

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author name string

Hui Chen

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Liang-Qing Li

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Dun Pan

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

15 October 2015

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Europe PubMed Central

PMC publication ID

13 August 2017

Oncology Letters

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Europe PubMed Central

PMC publication ID

13 August 2017

10

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Europe PubMed Central

PMC publication ID

13 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

3732-3736

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma

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MicroRNA-143 inhibits migration and invasion of human non-small-cell lung cancer and its relative mechanism

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Inhibition of HSP90 with AUY922 induces synergy in HER2-amplified trastuzumab-resistant breast and gastric cancer

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Targeting PI3K/Akt/HSP90 signaling sensitizes gastric cancer cells to deoxycholate-induced apoptosis

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Activation of the Akt survival pathway contributes to TRAIL resistance in cancer cells

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Update on Hsp90 inhibitors in clinical trial.

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Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: New findings and review of the literature

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Targeting HSP90 for cancer therapy

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Dual targeting of HSC70 and HSP72 inhibits HSP90 function and induces tumor-specific apoptosis

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Hsp90 inhibition transiently activates Src kinase and promotes Src-dependent Akt and Erk activation

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Hsp90: a novel target for cancer therapy

1 reference

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V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors

1 reference

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30 September 2017

Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin

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Targeting multiple signal transduction pathways through inhibition of Hsp90.

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The Hsp90 chaperone complex as a novel target for cancer therapy

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Akt forms an intracellular complex with heat shock protein 90 (Hsp90) and Cdc37 and is destabilized by inhibitors of Hsp90 function

1 reference

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HSP90 as a new therapeutic target for cancer therapy: the story unfolds

1 reference

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Inhibition of signal transduction by the Hsp90 inhibitor 17-allylamino-17-demethoxygeldanamycin results in cytostasis and apoptosis.

1 reference

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The co-chaperone CHIP regulates protein triage decisions mediated by heat-shock proteins

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Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

1 reference

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Identification and characterization of a new member of the TNF family that induces apoptosis

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The epidemiology of gastric cancer

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heat-shock protein 90 inhibitors as novel cancer chemotherapeutic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/26788199

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3892/OL.2015.3807

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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