Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF). (Q36270374)

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English	Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF).	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

13 August 2017

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1 reference

Europe PubMed Central

Is intravenous immunoglobulins (IVIG) efficacious in early pregnancy failure? A critical review and meta-analysis for patients who fail in vitro fertilization and embryo transfer (IVF). (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

author name string

David A Clark

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Carolyn B Coulam

2

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Raphael B Stricker

3

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

publication date

19 January 2006

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Journal of Assisted Reproduction and Genetics

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

23

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1-13

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Natural killer cells, miscarriage, and infertility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Cytokines, implantation and early abortion: re-examining the Th1/Th2 paradigm leads to question the single pathway, single therapy concept.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Characterization of the CD200 receptor family in mice and humans and their interactions with CD200.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

IVIG--mechanisms of action.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Is there any evidence for immunologically mediated or immunologically modifiable early pregnancy failure?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Correlation of NK cell activation and inhibition markers with NK cytoxicity among women experiencing immunologic implantation failure after in vitro fertilization and embryo transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Immunomodulatory action of intravenous immunoglobulin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Unexplained sporadic and recurrent miscarrage in the new millennium: a critical analysis of immune mechanisms and treatments.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Comparison of evidence of treatment effects in randomized and nonrandomized studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Procoagulants in fetus rejection: the role of the OX-2 (CD200) tolerance signal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

The role of gamma/delta T cells in the feto-maternal relationship

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Randomized, controlled trials, observational studies, and the hierarchy of research designs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

A comparison of observational studies and randomized, controlled trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Peripheral blood mononuclear cells from women with recurrent abortion exhibit an aberrant reaction to release cytokines upon the direct contact of human leukocyte antigen-G-expressing cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Immunotherapy for recurrent pregnancy loss: analysis of results from clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Recommendations for off-label use of intravenously administered immunoglobulin preparations. University Hospital Consortium Expert Panel for Off-Label Use of Polyvalent Intravenously Administered Immunoglobulin Preparations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Preconceptional natural-killer-cell activity as a predictor of miscarriage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

30 September 2017

Successful treatment of immunologic abortion with low-dose intravenous immunoglobulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

29 June 2018

The use of allogeneic leukocytes or i.v. IgG for the treatment of patients with recurrent spontaneous abortions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

29 June 2018

Intravenous immunoglobulin therapy for recurrent spontaneous abortion: a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS10815-005-9013-1

21 January 2018

The use of combined heparin/aspirin and immunoglobulin G therapy in the treatment of in vitro fertilization patients with antithyroid antibodies

1 reference

https://api.crossref.org/works/10.1007%2FS10815-005-9013-1

21 January 2018

Secretion of interleukin-2 from unstimulated peripheral blood mononuclear cells is a possible pathogenic mechanism in recurrent abortion

1 reference

https://api.crossref.org/works/10.1007%2FS10815-005-9013-1

21 January 2018

Reduced uterine indoleamine 2,3-dioxygenase versus increased Th1/Th2 cytokine ratios as a basis for occult and clinical pregnancy failure in mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Ecology of danger-dependent cytokine-boosted spontaneous abortion in the CBA x DBA/2 mouse model. I. Synergistic effect of LPS and (TNF-alpha + IFN-gamma) on pregnancy loss

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

The fgl2 prothrombinase/fibroleukin gene is required for lipopolysaccharide-triggered abortions and for normal mouse reproduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Increasing circulating T-cell activation markers are linked to subsequent implantation failure after transfer of in vitro fertilized embryos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

MD-1 is a critical part of the mechanism causing Th1-cytokine-triggered murine fetal loss syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Assisted reproductive technology in the United States: 1999 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Activation of the novel prothrombinase, fg12, as a basis for the pregnancy complications spontaneous abortion and pre-eclampsia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Elevated cytotoxicity in combat veterans with long-term post-traumatic stress disorder: preliminary observations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Gamma delta T cells of human early pregnancy decidua: evidence for local proliferation, phenotypic heterogeneity, and extrathymic differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Assessment of numeric abnormalities of X, Y, 18, and 16 chromosomes in preimplantation human embryos before transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

22 September 2018

Augmented induction of CD4+CD25+ Treg using monoclonal antibodies to CD200R

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3455429

21 October 2018

"In silico experiments"--yes, but the great western cowboy "random chance" is still alive

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"In silico experiments"--yes, but the great western cowboy "random chance" is still alive

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

"In silico experiments"--yes, but the great western cowboy "random chance" is still alive

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GM-CSF and pregnancy: evidence of significantly reduced blood concentrations in unexplained recurrent abortion efficiently reverted by intravenous immunoglobulin treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pre-conceptional natural killer cell activity and percentage as predictors of biochemical pregnancy and spontaneous abortion with normal chromosome karyotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Acts Independently of the Beta Common Subunit of the GM-CSF Receptor to Prevent Inner Cell Mass Apoptosis in Human Embryos1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased T helper 1 cytokine responses by circulating T cells are present in women with recurrent pregnancy losses and in infertile women with multiple implantation failures after IVF

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Intravenous Immunoglobulin Treatment on the Th1/Th2 Balance in Women with Recurrent Spontaneous Abortions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical analysis of intravenous immunoglobulin therapy for recurrent miscarriage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antiphospholipid antibody status and IVF--debate

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of repeated unexplained in vitro fertilization failure with intravenous immunoglobulin: a randomized, placebo-controlled Canadian trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fgl2 prothrombinase expression in mouse trophoblast and decidua triggers abortion but may be countered by OX-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulatory T cells mediate maternal tolerance to the fetus

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-thyroid antibodies and antiphospholipid syndrome: evidence of reduced fecundity and of poor pregnancy outcome in recurrent spontaneous aborters

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stress-triggered abortion in mice prevented by alloimmunization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous immunoglobulin (IVIG) in the prevention of implantation failures

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Worldwide collaborative observational study and meta-analysis on allogenic leukocyte immunotherapy for recurrent spontaneous abortion. Recurrent Miscarriage Immunotherapy Trialists Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous immunoglobulin in the prevention of recurrent miscarriage. The German RSA/IVIG Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High fecundity rates following in-vitro fertilization and embryo transfer in antiphospholipid antibody seropositive women treated with heparin and aspirin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T-helper 1-type immunity to trophoblast in women with recurrent spontaneous abortion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Placebo-controlled trial of treatment of unexplained secondary recurrent spontaneous abortions and recurrent late spontaneous abortions with i.v. immunoglobulin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous immunoglobulin for treatment of recurrent pregnancy loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endometrial T, B, and NK cells in patients with recurrent spontaneous abortion. Altered profile and pregnancy outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevated peripheral blood natural killer cells are effectively downregulated by immunoglobulin G infusion in women with recurrent spontaneous abortions

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravenous immunoglobulin inhibits natural killer cell activity in vivo in women with recurrent spontaneous abortion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Implication of abnormal human trophoblast karyotype for the evidence-based approach to the understanding, investigation, and treatment of recurrent spontaneous abortion. The Recurrent Miscarriage Immunotherapy Trialists Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of intravenous immunoglobulin G on natural killer cell cytotoxicity in vitro in women with recurrent spontaneous abortion

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The use of intravenous immunoglobulin in recurrent pregnancy loss associated with combined alloimmune and autoimmune abnormalities

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of antiphospholipid antibodies in women undergoing in-vitro fertilization: role of heparin and aspirin

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Short-term therapy for recurrent abortion using intravenous immunoglobulins: results of a double-blind placebo-controlled Italian study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of unexplained recurrent spontaneous abortion using intravenous immunoglobulin: a prospective, randomized, double-blinded, placebo-controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The selective use of heparin/aspirin therapy, alone or in combination with intravenous immunoglobulin G, in the management of antiphospholipid antibody-positive women undergoing in vitro fertilization

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of recurrent spontaneous abortion by intravenous immunoglobulin: a double-blind placebo-controlled study

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of surface CD200 on stored allogeneic leukocytes may impair anti-abortive effect in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A randomized, double-blind, placebo-controlled trial of intravenous immunoglobulin in the prevention of recurrent miscarriage: evidence for a therapeutic effect in women with secondary recurrent miscarriage

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An optimized technique for separation of human decidual leukocytes for cellular and molecular analyses

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant IL-10 and TGF-beta mRNA expression in gammadeltaT cells of human early pregnancy decidua suggests immunoregulatory potential

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TH1/TH2,3 imbalance due to cytokine-producing NK, gammadelta T and NK-gammadelta T cells in murine pregnancy decidua in success or failure of pregnancy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16421767

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10815-005-9013-1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

ResearchGate publication ID

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