Deregulation of cell-signaling pathways in HTLV-1 infection (Q36254870)

13 August 2017

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title

Deregulation of cell-signaling pathways in HTLV-1 infection (English)

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Human T-lymphotropic virus 1

13 August 2017

main subject

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author name string

William W Hall

series ordinal

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13 August 2017

Masahiro Fujii

series ordinal

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13 August 2017

language of work or name

English

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publication date

1 September 2005

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13 August 2017

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13 August 2017

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13 August 2017

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13 August 2017

page(s)

5965-5975

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Human T-lymphotropic virus type 1 open reading frame I p12(I) is required for efficient viral infectivity in primary lymphocytes

13 August 2017

cites work

1 reference

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Activation of nuclear factor of activated T cells by human T-lymphotropic virus type 1 accessory protein p12(I).

21 January 2018

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Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis.

21 January 2018

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The HBZ factor of human T-cell leukemia virus type I dimerizes with transcription factors JunB and c-Jun and modulates their transcriptional activity

21 January 2018

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Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT)

21 January 2018

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PDZ domains: More than just a glue

21 January 2018

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Human Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type 1 and regulates envelope mediated cell-cell fusion in T lymphocytes

21 January 2018

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Human T-cell leukemia virus type II transforms normal human lymphocytes

21 January 2018

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Signal transmission between the plasma membrane and nucleus of T lymphocytes

21 January 2018

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Human T-cell lymphotropic virus type 1 p12(I) expression increases cytoplasmic calcium to enhance the activation of nuclear factor of activated T cells

21 January 2018

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Human T-cell lymphotropic virus type 1 p12I enhances interleukin-2 production during T-cell activation.

21 January 2018

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Human T-cell leukemia virus type 2 (HTLV-2) Tax protein transforms a rat fibroblast cell line but less efficiently than HTLV-1 Tax.

21 January 2018

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Identification of functional PDZ domain binding sites in several human proteins

21 January 2018

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PDZ domains: fundamental building blocks in the organization of protein complexes at the plasma membrane

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Activation of oncogenic transcription factor AP-1 in T cells infected with human T cell leukemia virus type 1.

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

c-fos promoter trans-activation by the tax1 protein of human T-cell leukemia virus type I

21 January 2018

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The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription

21 January 2018

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https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Development of leukemia in mice transgenic for the tax gene of human T-cell leukemia virus type I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

A transgenic mouse model for human neurofibromatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

In vivo cellular tropism of human T cell leukemia virus type II (HTLV-II).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Transcriptional regulation of the IL-2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Life, death, and tax: role of HTLV-I oncoprotein in genetic instability and cellular transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

A human suppressor of c-Jun N-terminal kinase 1 activation by tumor necrosis factor alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Induction of human T cell leukemia virus type I receptors on quiescent naive T lymphocytes by TGF-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Transactivation of the transforming growth factor beta 1 (TGF-beta 1) gene by human T lymphotropic virus type 1 tax: a potential mechanism for the increased production of TGF-beta 1 in adult T cell leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Binding of high-risk human papillomavirus E6 oncoproteins to the human homologue of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Role of the PDZ domain-binding motif of the oncoprotein E6 in the pathogenesis of human papillomavirus type 31

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Human T-cell lymphotropic virus type 1 tax inhibits transforming growth factor-beta signaling by blocking the association of Smad proteins with Smad-binding element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Multi-PDZ domain protein MUPP1 is a cellular target for both adenovirus E4-ORF1 and high-risk papillomavirus type 18 E6 oncoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Binding of human virus oncoproteins to hDlg/SAP97, a mammalian homolog of the Drosophila discs large tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Jaks and STATs: biological implications

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Transcriptional activation of human TR3/nur77 gene expression by human T-lymphotropic virus type I Tax protein through two AP-1-like elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

IFN regulatory factor 4 participates in the human T cell lymphotropic virus type I-mediated activation of the IL-15 receptor alpha promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Differential effect of TGF-beta 1 on the in vitro activation of HTLV-I and the proliferative response of CD8+ T lymphocytes in patients with HTLV-I-associated myelopathy (HAM/TSP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Specific interaction of HTLV tax protein and a human type IV neuronal intermediate filament protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Interferon regulatory factor 4 (IRF4) interacts with NFATc2 to modulate interleukin 4 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Involvement of NF-AT in type I human T-cell leukemia virus Tax-mediated Fas ligand promoter transactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Regulation of IFN regulatory factor 4 expression in human T cell leukemia virus-I-transformed T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Ternary complex factors and cofactors are essential for human T-cell leukemia virus type 1 tax transactivation of the serum response element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Interleukin-13 overexpression by tax transactivation: a potential autocrine stimulus in human T-cell leukemia virus-infected lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

In vitro cellular tropism of human T cell leukemia virus type 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Cytokine-induced apoptosis in epithelial HT-29 cells is independent of nitric oxide formation. Evidence for an interleukin-13-driven phosphatidylinositol 3-kinase-dependent survival mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Protein profile of tax-associated complexes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Constitutive activation of different Jak tyrosine kinases in human T cell leukemia virus type 1 (HTLV-1) tax protein or virus-transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

Human T-lymphotropic virus type II and neurological disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

T-Cell Growth Factor Gene: Lack of Expression in Human T-Cell Leukemia-Lymphoma Virus-Infected Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Role of Tax protein in human T-cell leukemia virus type-I leukemogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Cancer. Improved mouse models

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Localization of apical epithelial determinants by the basolateral PDZ protein Scribble

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Activation of STAT proteins and growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Ets ternary complex transcription factors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Limiting amounts of p27Kip1 correlates with constitutive activation of cyclin E-CDK2 complex in HTLV-I-transformed T-cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

PDZ proteins organize synaptic signaling pathways

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Signal transduction by the JNK group of MAP kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Gene expression array of HTLV type 1-infected T cells: Up-regulation of transcription factors and cell cycle genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Rho GTPases control migration and polarization of adhesion molecules and cytoskeletal ERM components in T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

X-I and X-II Open Reading Frames of HTLV-I Are Not Required for Virus Replication or for Immortalization of Primary T-Cellsin Vitro

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Interaction of HTLV-1 Tax1 with p67SRF causes the aberrant induction of cellular immediate early genes through CArG boxes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

c-Jun, c-Fos and their family members activate the transcription mediated by three 21-bp repetitive sequences in the HTLV-I long terminal repeat.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Interactions of the PDZ-protein MAGI-1 with adenovirus E4-ORF1 and high-risk papillomavirus E6 oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Inhibition of patterned cell shape change and cell invasion by Discs large during Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Gene expression profiles in HTLV-I-immortalized T cells: deregulated expression of genes involved in apoptosis regulation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

PDZ domain-binding motif of human T-cell leukemia virus type 1 Tax oncoprotein augments the transforming activity in a rat fibroblast cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

1 reference

7 January 2021

The APC-hDLG complex negatively regulates cell cycle progression from the G0/G1 to S phase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Human T-cell leukemia virus type 1 tax protein activates transcription through AP-1 site by inducing DNA binding activity in T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Augmentation of c-fos and c-jun expression in transgenic mice carrying the human T-cell leukemia virus type-I tax gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Induction of the HTLV-I LTR by Jun occurs through the Tax-responsive 21-bp elements

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Functional activities of the human T-cell leukemia virus type I Tax oncoprotein: cellular signaling through NF-kappa B.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Overexpression of transforming growth factor-beta in transgenic mice carrying the human T-cell lymphotropic virus type I tax gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

The role of Stat5a and Stat5b in signaling by IL-2 family cytokines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Phosphoinositide-3 kinase-PKB/Akt pathway activation is involved in fibroblast Rat-1 transformation by human T-cell leukemia virus type I tax.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

T-cell receptor stimulation elicits an early phase of activation and a later phase of deactivation of the transcription factor NFAT1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Repression of IRF-4 target genes in human T cell leukemia virus-1 infection

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

IRF-4 activities in HTLV-I-induced T cell leukemogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Evidence for aberrant activation of the interleukin-2 autocrine loop by HTLV-1-encoded p40x and T3/Ti complex triggering.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

HPV E6 specifically targets different cellular pools of its PDZ domain-containing tumour suppressor substrates for proteasome-mediated degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Human T-cell leukemia virus type I and adult T-cell leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Constitutively Activated Jak-STAT Pathway in T Cells Transformed with HTLV-I

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Multiple signalling pathways lead to the activation of the nuclear factor kappaB by the Rho family of GTPases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Activation of endogenous c-fos proto-oncogene expression by human T-cell leukemia virus type I-encoded p40tax protein in the human T-cell line, Jurkat

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Human T-cell leukemia virus type 1 Tax protein induces the expression of STAT1 and STAT5 genes in T-cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Genome-wide expression changes induced by HTLV-1 Tax: evidence for MLK-3 mixed lineage kinase involvement in Tax-mediated NF-kappaB activation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Human T-cell leukemia virus type 1 Tax oncoprotein induces and interacts with a multi-PDZ domain protein, MAGI-3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

DHR domains in syntrophins, neuronal NO synthases and other intracellular proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

The maternal effect of lethal(1)discs-large-1: a recessive oncogene of Drosophila melanogaster.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

HPV E6 targeted degradation of the discs large protein: evidence for the involvement of a novel ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

NF-ATp: a transcription factor required for the co-ordinate induction of several cytokine genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Immortalization of CD4(+) and CD8(+) T lymphocytes by human T-cell leukemia virus type 1 Tax mutants expressed in a functional molecular clone

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Rho GTPases: signaling, migration, and invasion

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

AP-1 as a regulator of cell life and death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Invasion of T-lymphoma cells: cooperation between Rho family GTPases and lysophospholipid receptor signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Tax oncoprotein of HTLV-1 binds to the human homologue of Drosophila discs large tumor suppressor protein, hDLG, and perturbs its function in cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

HBZ interacts with JunD and stimulates its transcriptional activity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Oncogenic human papillomavirus E6 proteins target the MAGI-2 and MAGI-3 proteins for degradation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

MUM1/IRF4 expression as a frequent event in mature lymphoid malignancies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

STAT signalling in cell proliferation and in development

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Binding of HTLV-1 tax oncoprotein to the precursor of interleukin-16, a T cell PDZ domain-containing protein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell line

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Multiple viral strategies of HTLV-1 for dysregulation of cell growth control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Differences in phosphorylation of the IL-2R associated JAK/STAT proteins between HTLV-I(+), IL-2-independent and IL-2-dependent cell lines and uncultured leukemic cells from patients with adult T-cell lymphoma/leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208975

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208975

1 reference

Dimensions Publication ID

13 August 2017

1013516230

0 references

1 reference