Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). (Q36243860)

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English	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	scientific article

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scholarly article

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8 February 2020

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (English)

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8 February 2020

haploinsufficiency

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based on heuristic

inferred from title

Parkinson's disease

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

4

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8 February 2020

Paulo A. Ferreira

5

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8 February 2020

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Kyoung-In Cho

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8 February 2020

Kelly Searle

2

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8 February 2020

Mason Webb

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21 July 2012

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8 February 2020

Cellular and Molecular Life Sciences

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69

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8 February 2020

3511-3527

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8 February 2020

Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells

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Neuroprotection and progenitor cell renewal in the injured adult murine retina requires healing monocyte-derived macrophages.

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Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress

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Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta

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Parkin ubiquitinates and promotes the degradation of RanBP2

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Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein

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Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription

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Ubc9 interacts with chicken ovalbumin upstream promoter-transcription factor I and represses receptor-dependent transcription

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MPTP toxicity: implications for research in Parkinson's disease

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Coenzyme A metabolism

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29 June 2018

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29 June 2018

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29 June 2018

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29 June 2018

MPTP produces reversible disappearance of tyrosine hydroxylase-containing retinal amacrine cells

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29 June 2018

Differences between subacute and chronic MPTP mice models: investigation of dopaminergic neuronal degeneration and alpha-synuclein inclusions.

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22 September 2018

Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various parkinsonian toxins.

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22 September 2018

Unregulated cytosolic dopamine causes neurodegeneration associated with oxidative stress in mice

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22 September 2018

Altered brain lipid composition in cyclooxygenase-2 knockout mouse

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22 September 2018

Morphological impairments in retinal neurons of the scotopic visual pathway in a monkey model of Parkinson's disease.

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22 September 2018

Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo.

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22 September 2018

Glia cell number modulates sensitivity to MPTP in mice

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22 September 2018

Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A.

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22 September 2018

The retina as a novel in vivo model for studying the role of molecules of the Bcl-2 family in relation to MPTP neurotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

MPTP susceptibility in the mouse: behavioral, neurochemical, and histological analysis of gender and strain differences.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

Developmental variation in the structure of the retina.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

The acute histopathology of MPTP in the mouse CNS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445802

22 September 2018

The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1071-9

21 January 2018

Oxygen radicals shaping evolution: Why fatty acid catabolism leads to peroxisomes while neurons do without it

1 reference

https://api.crossref.org/works/10.1007%2FS00018-012-1071-9

21 January 2018

Mice lacking ornithine-delta-aminotransferase have paradoxical neonatal hypoornithinaemia and retinal degeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of MPTP on the mouse retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal dopamine sensitivity to MPP+ toxicity: electrophysiological and biochemical evaluation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Uptake of the neurotoxin 1-methyl-4-phenylpyridine (MPP+) by mitochondria and its relation to the inhibition of the mitochondrial oxidation of NAD+-linked substrates by MPP+

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Serum lathosterol concentration is an indicator of whole-body cholesterol synthesis in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/22821000

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00018-012-1071-9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22821000%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

ResearchGate publication ID

0 references

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