Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells (Q36217325)

12 August 2017

Dynamin-mediated Nephrin phosphorylation regulates glucose-stimulated insulin release in pancreatic beta cells. (English)

1 reference

12 August 2017

1 reference

Tilo Moede

0 references

Camillo Ricordi

0 references

Per-Olof Berggren

1 reference

12 August 2017

Sandra Merscher-Gomez

object named as

Sandra Merscher-Gomez

1 reference

12 August 2017

Dony Maiguel

1 reference

12 August 2017

Rodrigo Villarreal

1 reference

12 August 2017

Jongmin Jeon

1 reference

12 August 2017

Ingo Leibiger

1 reference

12 August 2017

Britta Walter

1 reference

12 August 2017

Christian Faul

1 reference

12 August 2017

Johanna Guzman

1 reference

12 August 2017

Peter Mundel

1 reference

12 August 2017

Alessia Fornoni

1 reference

12 August 2017

language of work or name

English

0 references

publication date

20 June 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

inferred from page(s)

published in

1 reference

12 August 2017

287

1 reference

12 August 2017

1 reference

12 August 2017

28932-28942

1 reference

describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3436561/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Phase transitions in the assembly of multivalent signalling proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin regulates lamellipodia formation by assembling a protein complex that includes Ship2, filamin and lamellipodin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Podocyte Protein, Nephrin, Is a Substrate of Protein Tyrosine Phosphatase 1B

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Trans-interaction of nephrin and Neph1/Neph3 induces cell adhesion that associates with decreased tyrosine phosphorylation of nephrin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Direct dynamin-actin interactions regulate the actin cytoskeleton

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Phosphorylation of nephrin triggers its internalization by raft-mediated endocytosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin is expressed on the surface of insulin vesicles and facilitates glucose-stimulated insulin release

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Neph1 cooperates with nephrin to transduce a signal that induces actin polymerization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Dynamin is functionally coupled to insulin granule exocytosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Imaging synaptic vesicle exocytosis and endocytosis with FM dyes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Ever-expanding network of dynamin-interacting proteins

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

beta-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin ectodomain engagement results in Src kinase activation, nephrin phosphorylation, Nck recruitment, and actin polymerization

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin forms a complex with adherens junction proteins and CASK in podocytes and in Madin-Darby canine kidney cells expressing nephrin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Defective trafficking of nephrin missense mutants rescued by a chemical chaperone

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Regulating actin dynamics at membranes: a focus on dynamin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Clinical islet transplantation: advances and immunological challenges

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

The dynamin superfamily: universal membrane tubulation and fission molecules?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin promotes cell-cell adhesion through homophilic interactions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Neph1 and nephrin interaction in the slit diaphragm is an important determinant of glomerular permeability

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Clustering-induced tyrosine phosphorylation of nephrin by Src family kinases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin and CD2AP associate with phosphoinositide 3-OH kinase and stimulate AKT-dependent signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Fyn binds to and phosphorylates the kidney slit diaphragm component Nephrin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin and Neph1 co-localize at the podocyte foot process intercellular junction and form cis hetero-oligomers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

A dynamin-cortactin-Arp2/3 complex mediates actin reorganization in growth factor-stimulated cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Imaging actin and dynamin recruitment during invagination of single clathrin-coated pits

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

The large GTPase dynamin regulates actin comet formation and movement in living cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

1 October 2017

Dynamin at actin tails

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Interaction with podocin facilitates nephrin signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Involvement of lipid rafts in nephrin phosphorylation and organization of the glomerular slit diaphragm

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Unraveling the mechanisms of glomerular ultrafiltration: nephrin, a key component of the slit diaphragm

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Nephrin is specifically located at the slit diaphragm of glomerular podocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Pancreatic beta-cell-to-beta-cell interactions are required for integrated responses to nutrient stimuli: enhanced Ca2+ and insulin secretory responses of MIN6 pseudoislets.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndrome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Characterization of SNARE protein expression in beta cell lines and pancreatic islets.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436561

Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion

29 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Nephrin mediates actin reorganization via phosphoinositide 3-kinase in podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Nck links nephrin to actin in kidney podocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Decreased tyrosine phosphorylation of nephrin in rat and human nephrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

SRC-family kinase Fyn phosphorylates the cytoplasmic domain of nephrin and modulates its interaction with podocin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

PKC alpha mediates beta-arrestin2-dependent nephrin endocytosis in hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M112.389452

Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22718751

12 December 2020

inferred from PubMed ID database lookup

Nephrin Is Critical for the Action of Insulin on Human Glomerular Podocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22718751

12 December 2020

inferred from PubMed ID database lookup

Reduction in VEGF protein and phosphorylated nephrin associated with proteinuria in adriamycin nephropathy rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22718751

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1074/JBC.M112.389452

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22718751

1 reference