Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer (Q36202240)

12 August 2017

Scutellaria barbata D. Don inhibits tumor angiogenesis via suppression of Hedgehog pathway in a mouse model of colorectal cancer (English)

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12 August 2017

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Scutellaria barbata

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Lihui Wei

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12 August 2017

Jiumao Lin

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12 August 2017

Wei Xu

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12 August 2017

Qiaoyan Cai

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12 August 2017

Aling Shen

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12 August 2017

Zhenfeng Hong

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12 August 2017

Jun Peng

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12 August 2017

language of work or name

English

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publication date

25 July 2012

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International Journal of Molecular Sciences

12 August 2017

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12 August 2017

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12 August 2017

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12 August 2017

9419-9430

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Creative Commons Attribution 4.0 International

12 August 2017

start time

25 July 2012

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April 2022 Public Data File from Crossref

copyrighted

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cites work

Antitumor and anti-angiogenic activities of Scutellaria barbata extracts in vitro are partially mediated by inhibition of Akt/protein kinase B.

1 reference

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Mechanisms and functions of Hedgehog signalling across the metazoa

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

Hedgehog Signaling Drives Cellular Survival in Human Colon Carcinoma Cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

BZL101, a phytochemical extract from the Scutellaria barbata plant, disrupts proliferation of human breast and prostate cancer cells through distinct mechanisms dependent on the cancer cell phenotype.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

Angiogenesis inhibitors: current strategies and future prospects

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

Paracrine Hedgehog signaling in cancer

1 October 2017

1 reference

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Chinese medicinal herb Scutellaria barbata modulates apoptosis and cell survival in murine and human prostate cancer cells and tumor development in TRAMP mice

1 October 2017

1 reference

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Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

1 October 2017

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Hedgehog: functions and mechanisms

1 October 2017

1 reference

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Natural products as leads to anticancer drugs

1 October 2017

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Evidence for a novel feedback loop in the Hedgehog pathway involving Smoothened and Fused.

1 October 2017

1 reference

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Chemoprevention of Scutellaria bardata on human cancer cells and tumorigenesis in skin cancer

1 October 2017

1 reference

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Drug resistance, predictive markers and pharmacogenomics in colorectal cancer

1 October 2017

1 reference

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Inhibitory effects of a chemically standardized extract from Scutellaria barbata in human colon cancer cell lines, LoVo

1 October 2017

1 reference

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The Hedgehog response network: sensors, switches, and routers

1 October 2017

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The biology of VEGF and its receptors

1 October 2017

1 reference

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Tumor angiogenesis and accessibility: role of vascular endothelial growth factor

1 October 2017

1 reference

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Drug resistance in colon cancer.

1 October 2017

1 reference

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Gli proteins encode context-dependent positive and negative functions: implications for development and disease

1 October 2017

1 reference

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Predictive value of vascular endothelial growth factor (VEGF) in metastasis and prognosis of human colorectal cancer

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

Mechanisms of angiogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3431803

Methylene chloride fraction of Scutellaria barbata induces apoptosis in human U937 leukemia cells via the mitochondrial signaling pathway

1 October 2017

1 reference

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Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2). A reassessment using novel receptor-specific vascular endothelial growth factor mutants

22 September 2018

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22 September 2018

1 reference

https://api.crossref.org/works/10.3390%2FIJMS13089419

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22949805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

[Antitumor and immune-modulating effects of Scutellaria barbata extract in mice bearing hepatocarcinoma H22 cells-derived tumor]

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22949805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genotoxicity of several clinically used topoisomerase II inhibitors

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22949805

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3390/IJMS13089419

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22949805

1 reference