Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus (Q36176491)

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English	Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus	scientific article

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scholarly article

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PMC publication ID

12 August 2017

Cannabidiol, a non-psychotropic component of cannabis, attenuates vomiting and nausea-like behaviour via indirect agonism of 5-HT(1A) somatodendritic autoreceptors in the dorsal raphe nucleus (English)

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Europe PubMed Central

PMC publication ID

12 August 2017

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Sharon Anavi-Goffer

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S Anavi-Goffer

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Raphael Mechoulam

7

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R Mechoulam

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12 August 2017

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E M Rock

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12 August 2017

D Bolognini

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12 August 2017

C L Limebeer

3

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12 August 2017

M G Cascio

4

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12 August 2017

P J Fletcher

6

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12 August 2017

R G Pertwee

8

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12 August 2017

L A Parker

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12 August 2017

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publication date

1 April 2012

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12 August 2017

British Journal of Pharmacology

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12 August 2017

165

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PMC publication ID

12 August 2017

8

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

2620-2634

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Guide to Receptors and Channels (GRAC), 5th edition

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1 October 2017

The nonpsychoactive cannabinoid cannabidiol inhibits 5-hydroxytryptamine3A receptor-mediated currents in Xenopus laevis oocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423241

1 October 2017

Cannabidiol ameliorates cognitive and motor impairments in bile-duct ligated mice via 5-HT1A receptor activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423241

1 October 2017

Antidepressant-like effects of cannabidiol in mice: possible involvement of 5-HT1A receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423241

1 October 2017

Cannabidiol, a nonpsychotropic component of cannabis, inhibits cue-induced heroin seeking and normalizes discrete mesolimbic neuronal disturbances

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423241

1 October 2017

The FAAH inhibitor URB-597 interferes with cisplatin- and nicotine-induced vomiting in the Suncus murinus (house musk shrew)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423241

1 October 2017

Conditioned nausea in rats: assessment by conditioned disgust reactions, rather than conditioned taste avoidance

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1 October 2017

The role of the anterior insular cortex in ictal vomiting: a stereotactic electroencephalography study

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1 October 2017

Involvement of 5HT1A receptors in the anxiolytic-like effects of cannabidiol injected into the dorsolateral periaqueductal gray of rats

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1 October 2017

Inactivation of the interoceptive insula disrupts drug craving and malaise induced by lithium

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1 October 2017

The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin

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1 October 2017

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History of cannabis and its preparations in saga, science, and sobriquet

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1 October 2017

Receptor mechanism and antiemetic activity of structurally-diverse cannabinoids against radiation-induced emesis in the least shrew

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1 October 2017

Repeated treatment with cannabidiol but not Delta9-tetrahydrocannabinol has a neuroprotective effect without the development of tolerance

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1 October 2017

Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro

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1 October 2017

Inhibition of an equilibrative nucleoside transporter by cannabidiol: a mechanism of cannabinoid immunosuppression

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1 October 2017

Agonistic properties of cannabidiol at 5-HT1a receptors

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1 October 2017

Cannabidiol prevents cerebral infarction via a serotonergic 5-hydroxytryptamine1A receptor-dependent mechanism

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1 October 2017

Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism

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1 October 2017

The insula; further observations on its function

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1 October 2017

Taste avoidance and taste aversion: evidence for two different processes

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1 October 2017

The nonpsychoactive cannabis constituent cannabidiol is an oral anti-arthritic therapeutic in murine collagen-induced arthritis

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Cannabidiol and (-)Delta9-tetrahydrocannabinol are neuroprotective antioxidants

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Electromyographic analysis of the ingestion and rejection of sapid stimuli in the rat.

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21 January 2018

Chronically decerebrate rats demonstrate satiation but not bait shyness

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Inverse agonism of cannabinoid CB1 receptors potentiates LiCl‐induced nausea in the conditioned gaping model in rats

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Cannabinoids inhibit emesis through CB1 receptors in the brainstem of the ferret

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2 July 2018

8-OH-DPAT suppresses vomiting in the cat elicited by motion, cisplatin or xylazine

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2 July 2018

The anxiolytic-like effects of cannabidiol injected into the bed nucleus of the stria terminalis are mediated by 5-HT1A receptors

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23 September 2018

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23 September 2018

Differential effects of neurotoxin-induced lesions of the basolateral amygdala and central nucleus of the amygdala on lithium-induced conditioned disgust reactions and conditioned taste avoidance

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23 September 2018

The effect of cannabidiol and URB597 on conditioned gaping (a model of nausea) elicited by a lithium-paired context in the rat.

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23 September 2018

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23 September 2018

A comparative analysis of the potential of cannabinoids and ondansetron to suppress cisplatin-induced emesis in the Suncus murinus (house musk shrew).

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23 September 2018

Effect of cannabinoids on lithium-induced vomiting in the Suncus murinus (house musk shrew).

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23 September 2018

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23 September 2018

The 5-HT1A agonist 8-OH-DPAT dose-dependently interferes with the establishment and the expression of lithium-induced conditioned rejection reactions in rats

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23 September 2018

Effects of cannabinoids on lithium-induced conditioned rejection reactions in a rat model of nausea

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23 September 2018

(-)-Cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens

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23 September 2018

Cannabidiol, a non-psychoactive component of cannabis and its synthetic dimethylheptyl homolog suppress nausea in an experimental model with rats

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23 September 2018

Delta-9-tetrahydrocannabinol differentially suppresses cisplatin-induced emesis and indices of motor function via cannabinoid CB(1) receptors in the least shrew

1 reference

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23 September 2018

The antiemetic drug ondansetron interferes with lithium-induced conditioned rejection reactions, but not lithium-induced taste avoidance in rats.

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23 September 2018

Modulation of cocaine-induced locomotor activity, rears and head bobs by application of WAY100635 into the dorsal and median raphe nuclei of the rat.

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23 September 2018

Antiemetic effects of 5-HT1A agonists in the pigeon.

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23 September 2018

Presynaptic 5-HT autoreceptors on serotonergic cell bodies and/or dendrites but not terminals are of the 5-HT1A subtype

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23 September 2018

Antiemetic effects of serotonergic 5-HT1A-receptor agonists in Suncus murinus

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https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The pharmacology of the emetic response to upper gastrointestinal tract stimulation in Suncus murinus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somato-motor, autonomic and electrocorticographic responses to electrical stimulation of rhinencephalic and other structures in primates, cat, and dog; a study of responses from the limbic, subcallosal, orbito-insular, piriform and temporal cortex,

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

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Agonist and antagonist actions of (-)pindolol at recombinant, human serotonin1A (5-HT1A) receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Direct Immunohistochemical Evidence of the Existence of 5-HT1A Autoreceptors on Serotoninergic Neurons in the Midbrain Raphe Nuclei

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed treatment with cannabidiol has a cerebroprotective action via a cannabinoid receptor-independent myeloperoxidase-inhibiting mechanism

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of the 5-HT1A receptor agonist, 8-OH-DPAT, on motion-induced emesis in Suncus murinus

1 reference

https://pubmed.ncbi.nlm.nih.gov/21827451

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.2011.01621.X

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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