Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation. (Q36081721)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22546694%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

title

Enhanced expression of VEGF-A in β cells increases endothelial cell number but impairs islet morphogenesis and β cell proliferation (English)

1 reference

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30 January 2020

0 references

1 reference

1 reference

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30 January 2020

1 reference

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30 January 2020

Qing Cai

1 reference

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30 January 2020

Marcela Brissova

1 reference

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30 January 2020

Fong Cheng Pan

1 reference

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30 January 2020

Priyanka Brahmachary

1 reference

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30 January 2020

Alena Shostak

1 reference

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30 January 2020

Aramandla Radhika

1 reference

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30 January 2020

Greg Poffenberger

1 reference

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30 January 2020

Susan E Quaggin

1 reference

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30 January 2020

W Gray Jerome

1 reference

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30 January 2020

Daniel J Dumont

1 reference

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30 January 2020

Alvin C Powers

1 reference

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30 January 2020

language of work or name

English

0 references

publication date

24 April 2012

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30 January 2020

published in

Developmental Biology

1 reference

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30 January 2020

volume

367

1 reference

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30 January 2020

issue

1 reference

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30 January 2020

page(s)

40-54

1 reference

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Blood vessels restrain pancreas branching, differentiation and growth

30 January 2020

cites work

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2 October 2017

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Disruption of hepatocyte growth factor/c-Met signaling enhances pancreatic beta-cell death and accelerates the onset of diabetes

2 October 2017

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2 October 2017

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'Giving and taking': endothelial and beta-cells in the islets of Langerhans

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The effect of extracellular matrix components on the preservation of human islet function in vitro

2 October 2017

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Oxygen tension regulates pancreatic beta-cell differentiation through hypoxia-inducible factor 1alpha

2 October 2017

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Oxygen: a master regulator of pancreatic development?

2 October 2017

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Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice.

2 October 2017

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Real-time, multidimensional in vivo imaging used to investigate blood flow in mouse pancreatic islets

2 October 2017

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Hepatocyte growth factor enhances engraftment and function of nonhuman primate islets

2 October 2017

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Revascularization of transplanted islets: can it be improved?

2 October 2017

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Cell-matrix interactions improve beta-cell survival and insulin secretion in three-dimensional culture

2 October 2017

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Insulin protein and proliferation in ductal cells in the transplanted pancreas of patients with type 1 diabetes and recurrence of autoimmunity

2 October 2017

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Apoptosis: a review of programmed cell death

2 October 2017

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Hypoxia-mediated activation of Dll4-Notch-Hey2 signaling in endothelial progenitor cells and adoption of arterial cell fate

2 October 2017

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The vascular basement membrane: a niche for insulin gene expression and Beta cell proliferation

2 October 2017

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Hypoxia-regulated differentiation: let's step it up a Notch

2 October 2017

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Lasting longer without oxygen: The influence of hypoxia on Notch signaling

2 October 2017

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2 October 2017

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Donor islet endothelial cells participate in formation of functional vessels within pancreatic islet grafts

2 October 2017

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2 October 2017

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2 October 2017

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The pancreatic ductal epithelium serves as a potential pool of progenitor cells

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Inducible expression of vascular endothelial growth factor in adult mice causes severe proliferative retinopathy and retinal detachment

2 October 2017

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Correction of hyperglycemia in diabetic mice transplanted with reversibly immortalized pancreatic beta cells controlled by the tet-on regulatory system

2 October 2017

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Rescue of the early vascular defects in Tek/Tie2 null mice reveals an essential survival function

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Leakage-resistant blood vessels in mice transgenically overexpressing angiopoietin-1

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis

2 October 2017

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11 July 2018

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23 September 2018

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23 September 2018

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Vascular endothelial growth factor increases functional beta-cell mass by improvement of angiogenesis of isolated human and murine pancreatic islets

23 September 2018

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Vascular function and sphingosine-1-phosphate regulate development of the dorsal pancreatic mesenchyme

23 September 2018

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Elevated vascular endothelial growth factor production in islets improves islet graft vascularization.

23 September 2018

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Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan

23 September 2018

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Influence of VEGF on the Viability of Encapsulated Pancreatic Rat Islets after Transplantation in Diabetic Mice

23 September 2018

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Hepatocyte Growth Factor Gene Therapy for Pancreatic Islets in Diabetes: Reducing the Minimal Islet Transplant Mass Required in a Glucocorticoid-Free Rat Model of Allogeneic Portal Vein Islet Transplantation

23 September 2018

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Role of VEGF-A in vascularization of pancreatic islets

23 September 2018

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Adenovirus-mediated hepatocyte growth factor expression in mouse islets improves pancreatic islet transplant performance and reduces beta cell death

23 September 2018

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VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis

23 September 2018

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23 September 2018

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23 September 2018

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Reduction in pancreatic transcription factor PDX-1 impairs glucose-stimulated insulin secretion

23 September 2018

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23 September 2018

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Direct cell adhesion to the angiopoietins mediated by integrins

23 September 2018

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Embryonic development is disrupted by modest increases in vascular endothelial growth factor gene expression.

23 September 2018

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Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia

23 September 2018

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Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny

23 September 2018

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Blood flow to the rabbit pancreas with special reference to the islets of Langerhans.

23 September 2018

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Enhanced oxygenation promotes beta-cell differentiation in vitro

23 September 2018

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Transgenic expression of Angiopoietin 1 in the liver leads to changes in lymphatic and blood vessel architecture.

7 January 2021

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An endothelial-mesenchymal relay pathway regulates early phases of pancreas development

7 January 2021

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Angiopoietin-1 production in islets improves islet engraftment and protects islets from cytokine-induced apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.04.022

Increased vascularization in mice overexpressing angiopoietin-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.04.022

Neogenesis and proliferation of beta-cells induced by human betacellulin gene transduction via retrograde pancreatic duct injection of an adenovirus vector

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2012.04.022

Immunocytochemical localization of insulin-immunoreactive cells in the pancreatic ducts of rats treated with trypsin inhibitor

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22546694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chronic systemic delivery of angiopoietin-2 reveals a possible independent angiogenic effect

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22546694

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.YDBIO.2012.04.022

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22546694%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22546694%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

22546694

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22546694%20AND%20SRC:MED&resulttype=core&format=json