A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation (Q36066631)

12 August 2017

A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation (English)

1 reference

12 August 2017

1 reference

Surjit K Chandhoke

1 reference

12 August 2017

Mark S Mooseker

series ordinal

1 reference

12 August 2017

9 May 2012

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Molecular Biology of the Cell

12 August 2017

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12 August 2017

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12 August 2017

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12 August 2017

2468-2480

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describes a project that uses

12 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3386211/fullTextXML

inferred from PubMed Central ID database lookup

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Myosin-IXA regulates collective epithelial cell migration by targeting RhoGAP activity to cell-cell junctions

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Collective cell migration requires suppression of actomyosin at cell-cell contacts mediated by DDR1 and the cell polarity regulators Par3 and Par6.

2 October 2017

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Motorized RhoGAP myosin IXb (Myo9b) controls cell shape and motility

2 October 2017

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Myosin II isoforms identify distinct functional modules that support integrity of the epithelial zonula adherens

2 October 2017

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Head of myosin IX binds calmodulin and moves processively toward the plus-end of actin filaments

2 October 2017

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Endocytosis and recycling of tight junction proteins in inflammation

2 October 2017

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Collective cell migration in morphogenesis, regeneration and cancer

2 October 2017

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RhoA GTPase and F-actin dynamically regulate the permeability of Cx43-made channels in rat cardiac myocytes

2 October 2017

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p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration

2 October 2017

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Rho/Rho-associated kinase-II signaling mediates disassembly of epithelial apical junctions

2 October 2017

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Lamellipodial actin mechanically links myosin activity with adhesion-site formation

2 October 2017

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Myosin 1E interacts with synaptojanin-1 and dynamin and is involved in endocytosis

2 October 2017

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Genetic variation in myosin IXB is associated with ulcerative colitis

2 October 2017

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Nonmuscle myosin IIA-dependent force inhibits cell spreading and drives F-actin flow

2 October 2017

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Myosin at work: motor adaptations for a variety of cellular functions

2 October 2017

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Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect

2 October 2017

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Mechanism of IFN-gamma-induced endocytosis of tight junction proteins: myosin II-dependent vacuolarization of the apical plasma membrane

2 October 2017

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CX3CR1-mediated dendritic cell access to the intestinal lumen and bacterial clearance

2 October 2017

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Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

2 October 2017

1 reference

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Endotoxin inhibits intestinal epithelial restitution through activation of Rho-GTPase and increased focal adhesions

2 October 2017

1 reference

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A role for myosin-1A in the localization of a brush border disaccharidase

2 October 2017

1 reference

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A porous defense: the leaky epithelial barrier in intestinal disease.

2 October 2017

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Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms

2 October 2017

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Rocks: multifunctional kinases in cell behaviour

2 October 2017

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Intestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation

2 October 2017

1 reference

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Myosin IXb is a single-headed minus-end-directed processive motor

2 October 2017

1 reference

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Myosin-IXb is a single-headed and processive motor

2 October 2017

1 reference

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The tail of a yeast class V myosin, myo2p, functions as a localization domain

2 October 2017

1 reference

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Visualization of melanosome dynamics within wild-type and dilute melanocytes suggests a paradigm for myosin V function In vivo

2 October 2017

1 reference

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Human myosin-IXb is a mechanochemically active motor and a GAP for rho

2 October 2017

1 reference

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Rho GTPases and the actin cytoskeleton

2 October 2017

1 reference

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The Rat Myosin myr 5 Is a GTPase-activating Protein for Rho In Vivo: Essential Role of Arginine 1695

2 October 2017

1 reference

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Rho proteins play a critical role in cell migration during the early phase of mucosal restitution

2 October 2017

1 reference

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Identification of the Rho-binding domain of p160ROCK, a Rho-associated coiled-coil containing protein kinase

2 October 2017

1 reference

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Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)

2 October 2017

1 reference

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Regulation of myosin phosphatase by Rho and Rho-associated kinase (Rho-kinase)

2 October 2017

1 reference

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An in vitro model for the analysis of intestinal brush border assembly. II. Changes in expression and localization of brush border proteins during cell contact-induced brush border assembly in Caco-2BBe cells

2 October 2017

1 reference

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Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Characterization of the enterocyte-like brush border cytoskeleton of the C2BBe clones of the human intestinal cell line, Caco-2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

MYO9B polymorphisms in patients with inflammatory bowel disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Association between genetic variants in myosin IXB and Crohn's disease.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Native Myosin-IXb is a plus-, not a minus-end-directed motor.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Rho kinase regulates tight junction function and is necessary for tight junction assembly in polarized intestinal epithelia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

PKC-dependent regulation of transepithelial resistance: roles of MLC and MLC kinase.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Myr 7 is a novel myosin IX-RhoGAP expressed in rat brain

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Regulation of non-muscle myosin assembly by calmodulin-dependent light chain kinase.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Epithelial properties of human colonic carcinoma cell line Caco-2: electrical parameters.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3386211

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

5 December 2018

1 reference

12 December 2020

Activation of β1 Integrin Signaling Stimulates Tyrosine Phosphorylation of p190 and Membrane-protrusive Activities at Invadopodia

1 reference

12 December 2020

Abnormally differentiated subsets of intestinal macrophage play a key role in Th1-dominant chronic colitis through excess production of IL-12 and IL-23 in response to bacteria

1 reference

12 December 2020

Rho and Rho-kinase (ROCK) signaling in adherens and gap junction assembly in corneal epithelium

1 reference

12 December 2020

Identifiers

DOI

10.1091/MBC.E11-09-0803

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22573889

1 reference