Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death (Q36014637)

11 August 2017

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death (English)

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11 August 2017

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1 June 2020

Hong-Guang Xia

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1 June 2020

Jiefei Geng

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1 June 2020

Lorena Galan-Acosta

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1 June 2020

Xuemei Han

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1 June 2020

Yuan Guo

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1 June 2020

Bing Shan

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1 June 2020

Yaoyang Zhang

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1 June 2020

Erik Norberg

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1 June 2020

Tao Zhang

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1 June 2020

Lifeng Pan

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1 June 2020

Junli Liu

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1 June 2020

Jonathan L Coloff

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1 June 2020

Dimitry Ofengeim

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1 June 2020

Hong Zhu

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1 June 2020

Kejia Wu

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1 June 2020

Yu Cai

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1 June 2020

John R Yates

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1 June 2020

Zhengjiang Zhu

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1 June 2020

Junying Yuan

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1 June 2020

Helin Vakifahmetoglu-Norberg

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1 June 2020

language of work or name

English

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publication date

1 August 2015

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11 August 2017

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inferred from page(s)

published in

Journal of Cell Biology

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1 June 2020

volume

210

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1 June 2020

issue

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1 June 2020

page(s)

705-716

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Quantitative Proteomics of Human Fibroblasts with I1061T Mutation in Niemann-Pick C1 (NPC1) Protein Provides Insights into the Disease Pathogenesis

1 June 2020

cites work

1 reference

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Dual proteolytic pathways govern glycolysis and immune competence

2 October 2017

1 reference

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Targeting hexokinase II to mitochondria to modulate energy metabolism and reduce ischaemia-reperfusion injury in heart

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Chaperone-mediated autophagy degrades mutant p53.

2 October 2017

1 reference

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Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

FLT3 tyrosine kinase inhibitors in acute myeloid leukemia: clinical implications and limitations

2 October 2017

1 reference

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Research methods: Know when your numbers are significant

2 October 2017

1 reference

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Overexpression of ecdysoneless in pancreatic cancer and its role in oncogenesis by regulating glycolysis

2 October 2017

1 reference

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Chaperone-mediated autophagy: a unique way to enter the lysosome world

2 October 2017

1 reference

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Deconvoluting the context-dependent role for autophagy in cancer

2 October 2017

1 reference

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Autophagy: renovation of cells and tissues

2 October 2017

1 reference

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Modulation of AKT activity is associated with reversible dormancy in ascites-derived epithelial ovarian cancer spheroids

2 October 2017

1 reference

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Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Chaperone-mediated autophagy: selectivity pays off.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Tumor cell metabolism: cancer's Achilles' heel

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Ras, PI(3)K and mTOR signalling controls tumour cell growth

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

FMS-like tyrosine kinase 3 in normal hematopoiesis and acute myeloid leukemia

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Akt stimulates aerobic glycolysis in cancer cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

DTASelect and Contrast: tools for assembling and comparing protein identifications from shotgun proteomics

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Large-scale analysis of the yeast proteome by multidimensional protein identification technology

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

A rapid method to separate endosomes from lysosomal contents using differential centrifugation and hypotonic lysis of lysosomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

IkappaB is a substrate for a selective pathway of lysosomal proteolysis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

The structure of mammalian hexokinase-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Uptake and degradation of glyceraldehyde-3-phosphate dehydrogenase by rat liver lysosomes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

Aerobic Glycolysis Suppresses p53 Activity to Provide Selective Protection from Apoptosis upon Loss of Growth Signals or Inhibition of BCR-Abl

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4555813

27 July 2018

Identifiers

DOI

10.1083/JCB.201503044

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26323688%20AND%20SRC:MED&resulttype=core&format=json

1 June 2020

1 reference

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1 June 2020

PubMed publication ID

26323688

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26323688%20AND%20SRC:MED&resulttype=core&format=json