Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae (Q35947069)

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English	Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae	scientific article

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30 December 2019

Characterization of three classes of membrane proteins involved in fungal azole resistance by functional hyperexpression in Saccharomyces cerevisiae (English)

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30 December 2019

Saccharomyces cerevisiae

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membrane protein

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1

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30 December 2019

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30 December 2019

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30 December 2019

Richard D. Cannon

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30 December 2019

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Kyoko Niimi

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30 December 2019

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Brian C Monk

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30 December 2019

Koichi Tanabe

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30 December 2019

Masakazu Niimi

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30 December 2019

Yoshimasa Uehara

8

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30 December 2019

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18 May 2007

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30 December 2019

Eukaryotic Cell

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30 December 2019

6

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30 December 2019

7

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30 December 2019

1150-1165

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30 December 2019

Multiple molecular mechanisms for multidrug resistance transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay

1 reference

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2 October 2017

A "silent" polymorphism in the MDR1 gene changes substrate specificity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Heterozygosity and functional allelic variation in the Candida albicans efflux pump genes CDR1 and CDR2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Phenotypic effects of membrane protein overexpression in Saccharomyces cerevisiae

1 reference

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2 October 2017

Overexpression of Candida albicans CDR1, CDR2, or MDR1 does not produce significant changes in echinocandin susceptibility

1 reference

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2 October 2017

Functional analysis of fungal drug efflux transporters by heterologous expression in Saccharomyces cerevisiae.

1 reference

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2 October 2017

Enniatin has a new function as an inhibitor of Pdr5p, one of the ABC transporters in Saccharomyces cerevisiae

1 reference

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2 October 2017

Surface-active fungicidal D-peptide inhibitors of the plasma membrane proton pump that block azole resistance

1 reference

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2 October 2017

Advances in the production of human therapeutic proteins in yeasts and filamentous fungi

1 reference

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2 October 2017

Stable and complete overcoming of MDR1/P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

1 reference

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2 October 2017

Genome evolution in yeasts

1 reference

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2 October 2017

Chemosensitization of fluconazole resistance in Saccharomyces cerevisiae and pathogenic fungi by a D-octapeptide derivative

1 reference

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2 October 2017

Formation of stacked ER cisternae by low affinity protein interactions

1 reference

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2 October 2017

Progress in functional genomics approaches to antifungal drug target discovery

1 reference

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2 October 2017

Structure and function of efflux pumps that confer resistance to drugs

1 reference

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2 October 2017

The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin function

1 reference

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2 October 2017

Functional Similarities and Differences between Candida albicans Cdr1p and Cdr2p Transporters

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2 October 2017

Cystic fibrosis

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2 October 2017

A general strategy to uncover transcription factor properties identifies a new regulator of drug resistance in yeast.

1 reference

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2 October 2017

Candida glabrata ATP-binding cassette transporters Cdr1p and Pdh1p expressed in a Saccharomyces cerevisiae strain deficient in membrane transporters show phosphorylation-dependent pumping properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

A monomeric red fluorescent protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Mammalian ABC transporters in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Sulfonylurea receptor -1 (SUR1): genetic and metabolic evidences for a role in the susceptibility to type 2 diabetes mellitus

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2 October 2017

ATP-binding cassette (ABC) transporters in atherosclerosis

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2 October 2017

New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system.

1 reference

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2 October 2017

Multifunctionality of plant ABC transporters--more than just detoxifiers

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2 October 2017

Yeast--a panacea for the structure-function analysis of membrane proteins?

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Prevalence of molecular mechanisms of resistance to azole antifungal agents in Candida albicans strains displaying high-level fluconazole resistance isolated from human immunodeficiency virus-infected patients

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Fungal ABC proteins: pleiotropic drug resistance, stress response and cellular detoxification.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1951111

2 October 2017

Microbial fermentation-derived inhibitors of efflux-pump-mediated drug resistance

1 reference

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2 October 2017

A large-scale overexpression screen in Saccharomyces cerevisiae identifies previously uncharacterized cell cycle genes.

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2 October 2017

Protein production: feeding the crystallographers and NMR spectroscopists

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2 October 2017

Genome microarray analysis of transcriptional activation in multidrug resistance yeast mutants

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2 October 2017

Specific covalent labeling of recombinant protein molecules inside live cells

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2 October 2017

ATPase and multidrug transport activities of the overexpressed yeast ABC protein Yor1p

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2 October 2017

Clinical, cellular, and molecular factors that contribute to antifungal drug resistance.

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2 October 2017

Multiple efflux mechanisms are involved in Candida albicans fluconazole resistance

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2 October 2017

Yeast-enhanced green fluorescent protein (yEGFP): a reporter of gene expression in Candida albicans

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2 October 2017

Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters

1 reference

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2 October 2017

Candida albicans gene encoding resistance to benomyl and methotrexate is a multidrug resistance gene

1 reference

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2 October 2017

The efficiency of translation termination is determined by a synergistic interplay between upstream and downstream sequences in Saccharomyces cerevisiae.

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2 October 2017

The multidrug resistance gene PDR1 from Saccharomyces cerevisiae.

1 reference

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2 October 2017

A novel method of affinity-purifying proteins using a bis-arsenical fluorescein.

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11 July 2018

Overexpression of the MDR1 gene is sufficient to confer increased resistance to toxic compounds in Candida albicans

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24 September 2018

Characterization of Cdr1p, a major multidrug efflux protein of Candida albicans: purified protein is amenable to intrinsic fluorescence analysis.

1 reference

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24 September 2018

Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux.

1 reference

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24 September 2018

Phosphorylation of candida glabrata ATP-binding cassette transporter Cdr1p regulates drug efflux activity and ATPase stability.

1 reference

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24 September 2018

Tandem affinity purification of the Candida albicans septin protein complex.

1 reference

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24 September 2018

Reversal of antifungal resistance mediated by ABC efflux pumps from Candida albicans functionally expressed in yeast

1 reference

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24 September 2018

Synthesis of milbemycins alpha9, alpha10, alpha11, alpha12, alpha14, alpha15, alpha20, alpha21, alpha22, alpha23, alpha26, alpha27, delta(2,3),delta(4,26)-milbemycins A3, A4 from milbemycins A3, A4, and their acaricidal activities.

1 reference

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24 September 2018

Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole

1 reference

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24 September 2018

Identification and expression of multidrug resistance-related ABC transporter genes in Candida krusei

1 reference

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24 September 2018

Targeted gene disruption in Candida albicans wild-type strains: the role of the MDR1 gene in fluconazole resistance of clinical Candida albicans isolates.

1 reference

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24 September 2018

The transmembrane domain 10 of the yeast Pdr5p ABC antifungal efflux pump determines both substrate specificity and inhibitor susceptibility.

1 reference

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24 September 2018

A recyclable Candida albicans URA3 cassette for PCR product-directed gene disruptions.

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24 September 2018

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1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures by numbers

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of transcription regulating genes PDR1, pdr1-3 and PDR3 in pleiotropic drug resistance

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Three-dimensional reconstruction of the Saccharomyces cerevisiae multidrug resistance protein Pdr5p

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and phenotypic characterization of yeast PDR1 mutants that show hyperactive transcription of various ABC multidrug transporter genes

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergic effects of tactolimus and azole antifungal agents against azole-resistant Candida albican strains

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Yeast as a model system for anticancer drug discovery

1 reference

https://pubmed.ncbi.nlm.nih.gov/17513564

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/EC.00091-07

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17513564%20AND%20SRC:MED&resulttype=core&format=json

30 December 2019

PMC publication ID

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Europe PubMed Central

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30 December 2019

PubMed publication ID

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Europe PubMed Central

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30 December 2019

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