Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma. (Q35921479)

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22 January 2020

title

Topical ocular sodium 4-phenylbutyrate rescues glaucoma in a myocilin mouse model of primary open-angle glaucoma (English)

1 reference

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22 January 2020

main subject

sodium phenylbutyrate

1 reference

ChEBI release 2020-05-28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

Gulab S Zode

1 reference

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22 January 2020

Kevin E Bugge

1 reference

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22 January 2020

Kabhilan Mohan

1 reference

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22 January 2020

Sinisa D Grozdanic

1 reference

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22 January 2020

Joseph C Peters

1 reference

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22 January 2020

Demelza R Koehn

1 reference

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22 January 2020

language of work or name

English

0 references

publication date

21 March 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

Investigative Ophthalmology Visual Science

22 January 2020

published in

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22 January 2020

volume

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22 January 2020

issue

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22 January 2020

page(s)

1557-1565

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Clinical and experimental applications of sodium phenylbutyrate

22 January 2020

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Genes of the Unfolded Protein Response Pathway Harbor Risk Alleles for Primary Open Angle Glaucoma

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2 October 2017

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Gene expression profile analysis of 4-phenylbutyrate treatment of IB3-1 bronchial epithelial cell line demonstrates a major influence on heat-shock proteins

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2 October 2017

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2 October 2017

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2 October 2017

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A chemical chaperone, sodium 4-phenylbutyric acid, attenuates the pathogenic potency in human alpha-synuclein A30P + A53T transgenic mice.

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Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model

24 September 2018

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Myocilin binding to Hep II domain of fibronectin inhibits cell spreading and incorporation of paxillin into focal adhesions

24 September 2018

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Sodium 4-phenylbutyrate protects against cerebral ischemic injury.

24 September 2018

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Expression pattern and in situ localization of the mouse homologue of the human MYOC (GLC1A) gene in adult brain.

24 September 2018

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Primary open-angle glaucoma

24 September 2018

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Increased fetal hemoglobin in patients receiving sodium 4-phenylbutyrate

22 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22328638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Sodium 4-phenylbutyrate upregulates ENaC and sodium absorption in T84 cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22328638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Localization of MYOC transcripts in human eye and optic nerve by in situ hybridization

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22328638

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1167/IOVS.11-8837

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json

22 January 2020

PubMed publication ID

22328638

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22328638%20AND%20SRC:MED&resulttype=core&format=json