ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes (Q35921159)

11 August 2017

ROS constitute a convergence nexus in the development of IGF1 resistance and impaired wound healing in a rat model of type 2 diabetes (English)

1 reference

11 August 2017

1 reference

1 reference

Fahd Al-Mulla

0 references

Milad S Bitar

1 reference

11 August 2017

23 February 2012

1 reference

Disease Models & Mechanisms

11 August 2017

1 reference

11 August 2017

1 reference

11 August 2017

1 reference

11 August 2017

375-388

1 reference

PMC publication ID

3339831

Creative Commons Attribution 2.0 Generic

11 August 2017

start time

18 May 2021

1 reference

April 2022 Public Data File from Crossref

copyrighted

0 references

cites work

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The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetes

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Alterations of insulin signaling in type 2 diabetes: a review of the current evidence from humans

2 October 2017

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Cancer as an overhealing wound: an old hypothesis revisited

2 October 2017

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Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors

2 October 2017

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Role of insulin receptor substrate-1 serine 307 phosphorylation and adiponectin in adipose tissue insulin resistance in late pregnancy

2 October 2017

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In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro

2 October 2017

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Inflammation in wound repair: molecular and cellular mechanisms

2 October 2017

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Regulating insulin signaling and beta-cell function through IRS proteins

2 October 2017

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Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

2 October 2017

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Reactive oxygen species have a causal role in multiple forms of insulin resistance

2 October 2017

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Involvement of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in corneal fibroblasts during corneal wound healing

2 October 2017

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Inflammation, stress, and diabetes

2 October 2017

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Evidence for a link between IGF-I and cancer.

2 October 2017

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Lipoic acid as a potential therapy for chronic diseases associated with oxidative stress

2 October 2017

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Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells.

2 October 2017

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Pathophysiological and clinical importance of insulin-like growth factor-I with respect to bone metabolism.

2 October 2017

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Healing responses of skin and muscle in critical illness

2 October 2017

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JNK: a new therapeutic target for diabetes

2 October 2017

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The IGFI receptor gene: a molecular target for disrupted transcription factors

2 October 2017

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A central role for JNK in obesity and insulin resistance

2 October 2017

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c-Jun N-terminal kinase (JNK) mediates feedback inhibition of the insulin signaling cascade

2 October 2017

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Rate of generation of oxidative stress-related damage and animal longevity

2 October 2017

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New perspectives into the molecular pathogenesis and treatment of type 2 diabetes

2 October 2017

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Oxidative stress regulates collagen synthesis and matrix metalloproteinase activity in cardiac fibroblasts

2 October 2017

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Insulin and glucocorticoid-dependent suppression of the IGF-I system in diabetic wounds

2 October 2017

1 reference

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The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307)

2 October 2017

1 reference

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EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology

2 October 2017

1 reference

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Glucocorticoid dynamics and impaired wound healing in diabetes mellitus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Protective effects of a superoxide dismutase/catalase mimetic compound against paraquat pneumotoxicity in rat lung

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Akt blockade downregulates collagen and upregulates MMP1 in human dermal fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Time- and dose-dependent effects of chronic wound fluid on human adult dermal fibroblasts

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Oxidative stress--mediated alterations in glucose dynamics in a genetic animal model of type II diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Transforming growth factor beta induces increased directed cellular migration and tissue repair in rats

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Serum tumour necrosis factor alpha and insulin resistance in gastrointestinal cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Effects of decreased insulin-like growth factor-1 stimulation on hypoxia inducible factor 1-alpha protein synthesis and function during cutaneous repair in diabetic mice

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Hydrogen peroxide attenuates insulin-like growth factor-1 neuroprotective effect, prevented by minocycline

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Stimulation of steroid-suppressed cutaneous healing by repeated topical application of IGF-I: different mechanisms of action based upon the mode of IGF-I delivery

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Tissue factor as a link between wounding and tissue repair.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Alpha-lipoic acid mitigates insulin resistance in Goto-Kakizaki rats

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Evaluation of the probes 2′,7′-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Low-dose dexamethasone in the rat: a model to study insulin resistance

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Glucose disposal by insulin, but not IGF-1, is dependent on the hepatic parasympathetic nerves

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3339831

Increased wound-breaking strength induced by insulin-like growth factor I in combination with insulin-like growth factor binding protein-1

24 September 2018

1 reference

12 December 2020

Insulin sensitivity tested with a modified euglycemic technique in cats and rats

1 reference

12 December 2020

Insulin-Like Growth Factor-1 Reverses Diabetes-Induced Wound Healing Impairment in Rats

1 reference

12 December 2020

Protein carbonyl measurement by enzyme-linked immunosorbent assay

1 reference

12 December 2020

Oxidative stress induces IGF-I receptor signaling disturbances in cultured human dermal fibroblasts. A possible mechanism for collagen biosynthesis inhibition

1 reference

12 December 2020

Insulin-like Growth Factor-I signaling mechanisms, type I collagen and alpha smooth muscle actin in human fetal lung fibroblasts

1 reference

12 December 2020

1 reference

12 December 2020

Tissue dispersion and flow cytometry for the cellular analysis of wound healing

1 reference

12 December 2020

Identifiers

DOI

10.1242/DMM.007872

1 reference

11 August 2017

1 reference

PMC publication ID

3339831

11 August 2017

PubMed publication ID

22362362

1 reference

PMC publication ID

3339831