Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity (Q35895966)

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scientific article published on October 1, 1997

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English	Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity	scientific article published on October 1, 1997

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6 November 2019

Effects of mutations in the Exo III motif of the herpes simplex virus DNA polymerase gene on enzyme activities, viral replication, and replication fidelity (English)

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6 November 2019

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17 November 2024

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Y. T. Hwang

1

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17 November 2024

B. Y. Liu

2

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D. M. Coen

3

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C. B. Hwang

4

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1 October 1997

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6 November 2019

October 1997

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17 November 2024

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https://jvi.asm.org/content/jvi/71/10/7791.full.pdf

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17 November 2024

http://jvi.asm.org/cgi/content/abstract/71/10/7791

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17 November 2024

https://europepmc.org/articles/PMC192131

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17 November 2024

https://europepmc.org/articles/PMC192131?pdf=render

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17 November 2024

https://journals.asm.org/doi/pdf/10.1128/jvi.71.10.7791-7798.1997

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10.1128/JVI.71.10.7791-7798.1997

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17 November 2024

Journal of Virology

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6 November 2019

71

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6 November 2019

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6 November 2019

7791-7798

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6 November 2019

Mutations of Bacteria from Virus Sensitivity to Virus Resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

Herpes simplex virus type 1 DNA polymerase. Mutational analysis of the 3'-5'-exonuclease domain

1 reference

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11 July 2018

Mutations within conserved motifs in the 3'-5' exonuclease domain of herpes simplex virus DNA polymerase

1 reference

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11 July 2018

Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity

1 reference

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11 July 2018

The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

Genetic and biochemical studies of bacteriophage T4 DNA polymerase 3'-->5'-exonuclease activity.

1 reference

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11 July 2018

A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant

1 reference

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11 July 2018

Structural and functional organization of herpes simplex virus DNA polymerase investigated by limited proteolysis.

1 reference

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11 July 2018

Nucleotide sequence of the major early region of bacteriophage phi 29.

1 reference

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11 July 2018

Generation of genetic diversity in herpes simplex virus: An antimutator phenotype maps to the DNA polymerase locus

1 reference

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11 July 2018

Fine mapping and molecular cloning of mutations in the herpes simplex virus DNA polymerase locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

Characterization of the DNA polymerases induced by a group of herpes simplex virus type I variants selected for growth in the presence of phosphonoformic acid

1 reference

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11 July 2018

Evidence for control of herpes simplex virus mutagenesis by the viral DNA polymerase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I

1 reference

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11 July 2018

DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

1 reference

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11 July 2018

Human DNA polymerase alpha gene expression is cell proliferation dependent and its primary structure is similar to both prokaryotic and eukaryotic replicative DNA polymerases

1 reference

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11 July 2018

Primary structure of T4 DNA polymerase. Evolutionary relatedness to eucaryotic and other procaryotic DNA polymerases

1 reference

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11 July 2018

Cocrystal structure of an editing complex of Klenow fragment with DNA

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11 July 2018

Related functional domains in virus DNA polymerases

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The complete DNA sequence of varicella-zoster virus

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Homology between DNA polymerases of poxviruses, herpesviruses, and adenoviruses: nucleotide sequence of the vaccinia virus DNA polymerase gene

1 reference

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11 July 2018

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

1 reference

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11 July 2018

Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors

1 reference

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Identification of amino acids in herpes simplex virus DNA polymerase involved in substrate and drug recognition

1 reference

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Exonucleolytic proofreading

1 reference

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11 July 2018

Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.

1 reference

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11 July 2018

Structure and function of the Saccharomyces cerevisiae CDC2 gene encoding the large subunit of DNA polymerase III

1 reference

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11 July 2018

Human DNA polymerase alpha: predicted functional domains and relationships with viral DNA polymerases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

Functional interaction between the herpes simplex-1 DNA polymerase and UL42 protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=192131

11 July 2018

The herpes simplex virus type 1 UL42 gene product: a subunit of DNA polymerase that functions to increase processivity

1 reference

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Engineered herpes simplex virus DNA polymerase point mutants: the most highly conserved region shared among alpha-like DNA polymerases is involved in substrate recognition

1 reference

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DNA sequence of mutations induced in cells by herpes simplex virus type-1.

1 reference

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11 July 2018

Comparison of exonucleolytic activities of herpes simplex virus type-1 DNA polymerase and DNase

1 reference

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Isolation and characterization of herpes simplex virus mutants containing engineered mutations at the DNA polymerase locus

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Enzymatic activities of overexpressed herpes simplex virus DNA polymerase purified from recombinant baculovirus-infected insect cells

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A general structure for DNA-dependent DNA polymerases.

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DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies

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The 3'-5' exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction

1 reference

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Fidelity mechanisms in DNA replication

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Primary structure of the catalytic subunit of human DNA polymerase delta and chromosomal location of the gene

1 reference

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Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity

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Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site

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The 3' to 5' exonuclease activity located in the DNA polymerase delta subunit of Saccharomyces cerevisiae is required for accurate replication

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Properties of Herpes Simplex Virus DNA Polymerase and Characterization of Its Associated Exonuclease Activity

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An altered spectrum of herpes simplex virus mutations mediated by an antimutator DNA polymerase

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Nucleotide sequences from the adenovirus-2 genome.

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A conserved 3'----5' exonuclease active site in prokaryotic and eukaryotic DNA polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9311864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence favouring the hypothesis of a conserved 3'-5' exonuclease active site in DNA-dependent DNA polymerases

1 reference

https://pubmed.ncbi.nlm.nih.gov/9311864

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.71.10.7791-7798.1997

1 reference

National Center for Biotechnology Information

PubMed publication ID

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=9311864

17 November 2024

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9311864%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9311864%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

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