Catalytic antioxidants: a radical approach to new therapeutics (Q35808784)

10 August 2017

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title

Catalytic antioxidants: a radical approach to new therapeutics (English)

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10 August 2017

Brian J Day

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10 August 2017

publication date

1 July 2004

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10 August 2017

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10 August 2017

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10 August 2017

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10 August 2017

page(s)

557-566

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Activation of the JAK-STAT pathway by reactive oxygen species.

10 August 2017

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Redox-dependent signal transduction

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7 January 2021

Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide

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7 January 2021

The Biology and Pathology of Oxygen Radicals

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7 January 2021

Free radicals and antioxidants in cardiovascular disease

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7 January 2021

Superoxide dismutases in the lung and human lung diseases

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7 January 2021

Reactive oxygen species and the central nervous system

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7 January 2021

Transgenic models for the study of lung antioxidant defense: enhanced manganese-containing superoxide dismutase activity gives partial protection to B6C3 hybrid mice exposed to hyperoxia

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7 January 2021

Aerosolized manganese SOD decreases hyperoxic pulmonary injury in primates. I. Physiology and biochemistry

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7 January 2021

Administration of bovine superoxide dismutase fails to prevent chronic pulmonary sequelae of neonatal oxygen exposure in the rat

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7 January 2021

Flavin-dependent antioxidant properties of a new series of meso-N,N'-dialkyl-imidazolium substituted manganese(III) porphyrins

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7 January 2021

Salen-manganese complexes: combined superoxide dismutase/catalase mimics with broad pharmacological efficacy

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7 January 2021

Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics

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7 January 2021

Compounds I of catalase and horse radish peroxidase: pi-cation radicals

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7 January 2021

Manganic Porphyrins Possess Catalase Activity and Protect Endothelial Cells against Hydrogen Peroxide-Mediated Injury

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7 January 2021

Metalloporphyrin class of therapeutic catalytic antioxidants

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7 January 2021

Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: structure-activity relationship studies

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7 January 2021

SOD mimetics are coming of age.

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7 January 2021

Superoxide dismutase delays neuronal apoptosis: a role for reactive oxygen species in programmed neuronal death

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7 January 2021

Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells

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7 January 2021

Control of Bcl-2 expression by reactive oxygen species

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7 January 2021

Impaired endothelial regulation of ventricular relaxation in cardiac hypertrophy: role of reactive oxygen species and NADPH oxidase

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7 January 2021

Hypercholesterolemia impairs endothelium-dependent relaxations in common carotid arteries of apolipoprotein e-deficient mice

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7 January 2021

Protein tyrosine nitration in mouse peritoneal macrophages activated in vitro and in vivo: evidence against an essential role of peroxynitrite

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7 January 2021

Synthesis and in vitro antioxidant properties of manganese(III) beta-octabromo-meso-tetrakis(4-carboxyphenyl)porphyrin

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Influence of tissue maturation and antioxidants on the apoptotic response of articular cartilage after injurious compression

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Iron toxicity in organotypic cultures of hippocampal slices: role of reactive oxygen species

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Role of polyamine metabolism in kainic acid excitotoxicity in organotypic hippocampal slice cultures

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7 January 2021

Involvement of reactive oxygen species in angiotensin II-induced vasoconstriction

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Superoxide dismutase mimetic M40403 improves endothelial function in apolipoprotein(E)-deficient mice

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Attenuation of bleomycin-induced pulmonary fibrosis by a catalytic antioxidant metalloporphyrin

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A small molecular weight catalytic metalloporphyrin antioxidant with superoxide dismutase (SOD) mimetic properties protects lungs from radiation-induced injury.

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7 January 2021

Inhibition of tobacco smoke-induced lung inflammation by a catalytic antioxidant

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Inhibition of airway inflammation and hyperreactivity by an antioxidant mimetic

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7 January 2021

Evidence for extracellular superoxide dismutase as a mediator of hemorrhage-induced lung injury

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7 January 2021

A catalytic antioxidant attenuates alveolar structural remodeling in bronchopulmonary dysplasia

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7 January 2021

Pharmacological manipulation of the inflammatory cascade by the superoxide dismutase mimetic, M40403

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Superoxide dismutase mimetics with catalase activity reduce the organ injury in hemorrhagic shock

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A nonpeptidyl mimic of superoxide dismutase, M40403, inhibits dose-limiting hypotension associated with interleukin-2 and increases its antitumor effects

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7 January 2021

Modulation of serum cytokine levels by a novel superoxide dismutase mimetic, M40401, in an Escherichia coli model of septic shock: correlation with preserved circulating catecholamines

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7 January 2021

A superoxide dismutase mimetic with catalase activity (EUK-8) reduces the organ injury in endotoxic shock

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7 January 2021

Interaction among nitric oxide, reactive oxygen species, and antioxidants during endotoxemia-related acute renal failure

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7 January 2021

Beneficial effects of peroxynitrite decomposition catalyst in a rat model of splanchnic artery occlusion and reperfusion

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7 January 2021

Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo

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7 January 2021

Cardioprotection by chronic estrogen or superoxide dismutase mimetic treatment in the aged female rat.

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7 January 2021

Detoxification of reactive oxygen species by a nonpeptidyl mimic of superoxide dismutase cures acetaminophen-induced acute liver failure in the mouse

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

The superoxide dismutase mimetic MnTBAP prevents Fas-induced acute liver failure in the mouse

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Regulation of postischemic liver injury following different durations of ischemia

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

EUK-134 reduces renal dysfunction and injury caused by oxidative and nitrosative stress of the kidney

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Novel antioxidants zolimid and AEOL11201 ameliorate colitis in rats

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Protective effects of M40403, a superoxide dismutase mimetic, in a rodent model of colitis

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A metalloporphyrin-based superoxide dismutase mimic inhibits adoptive transfer of autoimmune diabetes by a diabetogenic T-cell clone

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Amelioration of joint disease in a rat model of collagen-induced arthritis by M40403, a superoxide dismutase mimetic

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Synthetic superoxide dismutase/catalase mimetics reduce oxidative stress and prolong survival in a mouse amyotrophic lateral sclerosis model

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A beta-peptides enhance vasoconstriction in cerebral circulation

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Exogenous A beta1-40 reproduces cerebrovascular alterations resulting from amyloid precursor protein overexpression in mice

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Mitochondrial superoxide production in kainate-induced hippocampal damage

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

The attenuation of vasospasm by using a sod mimetic after experimental subarachnoidal haemorrhage in rats

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Neuroprotection from delayed postischemic administration of a metalloporphyrin catalytic antioxidant.

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7 January 2021

Effects of metalloporphyrin catalytic antioxidants in experimental brain ischemia

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Protein and DNA oxidation in spinal injury: neurofilaments--an oxidation target

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7 January 2021

The role of reactive nitrogen species in secondary spinal cord injury: formation of nitric oxide, peroxynitrite, and nitrated protein

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7 January 2021

A newly identified role for superoxide in inflammatory pain

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics

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7 January 2021

Inactivation of catecholamines by superoxide gives new insights on the pathogenesis of septic shock

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Oxygen-derived free radicals in postischemic tissue injury

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A catalytic antioxidant metalloporphyrin blocks hydrogen peroxide-induced mitochondrial DNA damage

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Dependence of excitotoxic neurodegeneration on mitochondrial aconitase inactivation

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7 January 2021

Reactive oxygen species differentially affect T cell receptor-signaling pathways.

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7 January 2021

The role of superoxide and nuclear factor-kappaB signaling in N-methyl-D-aspartate-induced necrosis and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

M40403, a superoxide dismutase mimetic, protects cochlear hair cells from gentamicin, but not cisplatin toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Metalloporphyrins improve the survival of Sod2-deficient neurons

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Gr-1+ myeloid cells derived from tumor-bearing mice inhibit primary T cell activation induced through CD3/CD28 costimulation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Attenuation of staurosporine-induced apoptosis, oxidative stress, and mitochondrial dysfunction by synthetic superoxide dismutase and catalase mimetics, in cultured cortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Reactive oxygen species are required for hyperoxia-induced Bax activation and cell death in alveolar epithelial cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Diesel exhaust particle-induced cell death of cultured normal human bronchial epithelial cells

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Attenuation of zinc-induced intracellular dysfunction and neurotoxicity by a synthetic superoxide dismutase/catalase mimetic, in cultured cortical neurons

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Reactive oxygen species mediate amplitude-dependent hypertrophic and apoptotic responses to mechanical stretch in cardiac myocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Caspase‐3 dependent proteolytic activation of protein kinase Cδ mediates and regulates 1‐methyl‐4‐phenylpyridinium (MPP+)‐induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Prevention of 1-methyl-4-phenylpyridinium- and 6-hydroxydopamine-induced nitration of tyrosine hydroxylase and neurotoxicity by EUK-134, a superoxide dismutase and catalase mimetic, in cultured dopaminergic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Peroxynitrite flux-mediated LDL oxidation is inhibited by manganese porphyrins in the presence of uric acid.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Reactive oxygen species scavengers attenuate endotoxin-induced impairment of hypoxic pulmonary vasoconstriction in mice

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Blockade of phencyclidine-induced cortical apoptosis and deficits in prepulse inhibition by M40403, a superoxide dismutase mimetic

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

Meningitis-associated hearing loss: protection by adjunctive antioxidant therapy

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

A role for superoxide in gentamicin-mediated nephropathy in rats

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https://api.crossref.org/works/10.1016%2FS1359-6446%2804%2903139-3

7 January 2021

10.1016/S1359-6446(04)03139-3

Identifiers

DOI

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10 August 2017

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