Gastric cancer stem cells: evidence, potential markers, and clinical implications (Q35795934)

10 August 2017

title

Gastric cancer stem cells: evidence, potential markers, and clinical implications (English)

1 reference

10 August 2017

main subject

neoplastic stem cells

1 reference

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Daniel Brungs

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Morteza Aghmesheh

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Kara L Vine

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Martin G Carolan

series ordinal

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

publication date

1 October 2015

1 reference

Journal of Gastroenterology

10 August 2017

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

313-326

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26428661%20AND%20SRC:MED&resulttype=core&format=json

Global cancer statistics, 2012

4 June 2020

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High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability.

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De-novo expression of CD44 and survival in gastric cancer

21 January 2018

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Clinicopathologic significance of putative stem cell marker, CD44 and CD133, in human gastric carcinoma

21 January 2018

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The rejuvenated scenario of epithelial-mesenchymal transition (EMT) and cancer metastasis

21 January 2018

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Cancer stem cells: mirage or reality?

21 January 2018

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The epithelial-mesenchymal transition generates cells with properties of stem cells

21 January 2018

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Generation of breast cancer stem cells through epithelial-mesenchymal transition

21 January 2018

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Cancer stem cell characteristics of circulating tumor cells

21 January 2018

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Identification of cancer stem cells in vincristine preconditioned SGC7901 gastric cancer cell line

21 January 2018

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The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

21 January 2018

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Critical appraisal of the side population assay in stem cell and cancer stem cell research

21 January 2018

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Not all side population cells contain cancer stem-like cells in human gastric cancer cell lines

21 January 2018

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Cancer stem cell-like SP cells have a high adhesion ability to the peritoneum in gastric carcinoma

21 January 2018

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Side population cells isolated from KATO III human gastric cancer cell line have cancer stem cell-like characteristics

21 January 2018

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Side populations of gastrointestinal cancers are not enriched in stem cells

21 January 2018

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Multipotential stem cells in adult mouse gastric epithelium

21 January 2018

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Lgr5 expression as stem cell marker in human gastric gland and its relatedness with other putative cancer stem cell markers

21 January 2018

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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

21 January 2018

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Prospective identification of a multilineage progenitor in murine stomach epithelium

21 January 2018

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Sox2+ Adult Stem and Progenitor Cells Are Important for Tissue Regeneration and Survival of Mice

21 January 2018

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Differentiated Troy+ chief cells act as reserve stem cells to generate all lineages of the stomach epithelium

21 January 2018

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SOX2, a predictor of survival in gastric cancer, inhibits cell proliferation and metastasis by regulating PTEN.

21 January 2018

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21 January 2018

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The stem cell factor SOX2 regulates the tumorigenic potential in human gastric cancer cells

21 January 2018

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SOX2 is frequently downregulated in gastric cancers and inhibits cell growth through cell-cycle arrest and apoptosis

21 January 2018

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21 January 2018

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K-ras Mutation Targeted to Gastric Tissue Progenitor Cells Results in Chronic Inflammation, an Altered Microenvironment, and Progression to Intraepithelial Neoplasia

21 January 2018

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Helicobacter pylori generates cells with cancer stem cell properties via epithelial-mesenchymal transition-like changes

21 January 2018

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Identification of a bone marrow-derived mesenchymal progenitor cell subset that can contribute to the gastric epithelium

21 January 2018

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Helicobacter pylori infection recruits bone marrow-derived cells that participate in gastric preneoplasia in mice.

21 January 2018

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Helicobacter pylori infection and stem cells at the origin of gastric cancer

21 January 2018

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CD44: from adhesion molecules to signalling regulators

21 January 2018

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CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers

21 January 2018

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CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth

21 January 2018

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CD133 and CD44 cell surface markers do not identify cancer stem cells in primary human gastric tumors

21 January 2018

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CD49f(high) cells retain sphere-forming and tumor-initiating activities in human gastric tumors

21 January 2018

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Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients

21 January 2018

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Identification of CD44+CD24+ gastric cancer stem cells

21 January 2018

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CD133: molecule of the moment

21 January 2018

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The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation

21 January 2018

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Aldehyde dehydrogenases and cell proliferation.

21 January 2018

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Coordinated expression of REG4 and aldehyde dehydrogenase 1 regulating tumourigenic capacity of diffuse-type gastric carcinoma-initiating cells is inhibited by TGF-β.

21 January 2018

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Hypoxia-mediated CD24 expression is correlated with gastric cancer aggressiveness by promoting cell migration and invasion

21 January 2018

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High expression of epithelial cellular adhesion molecule in peritoneal metastasis of gastric cancer

21 January 2018

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EpCAM is overexpressed in gastric cancer and its downregulation suppresses proliferation of gastric cancer

21 January 2018

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Murine hepatic stellate cells veto CD8 T cell activation by a CD54-dependent mechanism.

21 January 2018

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Trastuzumab (herceptin) targets gastric cancer stem cells characterized by CD90 phenotype.

21 January 2018

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Absence of CD71 transferrin receptor characterizes human gastric adenosquamous carcinoma stem cells.

21 January 2018

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Prognostic evaluation of Nanog, Oct4, Sox2, PCNA, Ki67 and E-cadherin expression in gastric cancer

21 January 2018

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Coexpression of HMGA2 and Oct4 predicts an unfavorable prognosis in human gastric cancer

21 January 2018

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Sequential expression of putative stem cell markers in gastric carcinogenesis

21 January 2018

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Expression and significance of CD44s, CD44v6, and nm23 mRNA in human cancer

21 January 2018

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Osteopontin, CD44, and NFkappaB expression in gastric adenocarcinoma

21 January 2018

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Prognostic value of cancer stem cell marker CD133 expression in gastric cancer: a systematic review

21 January 2018

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Prognostic value of circulating CD133(+) cells in patients with gastric cancer

21 January 2018

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CD44 expression denotes a subpopulation of gastric cancer cells in which Hedgehog signaling promotes chemotherapy resistance

21 January 2018

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5-Fluorouracil chemotherapy of gastric cancer generates residual cells with properties of cancer stem cells

21 January 2018

1 reference

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Effects and mechanisms of anti-CD44 monoclonal antibody A3D8 on proliferation and apoptosis of sphere-forming cells with stemness from human ovarian cancer

21 January 2018

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Functionalizing Liposomes with anti-CD44 Aptamer for Selective Targeting of Cancer Cells.

21 January 2018

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CD44 antibody-targeted liposomal nanoparticles for molecular imaging and therapy of hepatocellular carcinoma.

21 January 2018

1 reference

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Co-delivery of paclitaxel and gemcitabine via CD44-targeting nanocarriers as a prodrug with synergistic antitumor activity against human biliary cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

The effect of hyaluronic acid functionalized carbon nanotubes loaded with salinomycin on gastric cancer stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

CD44-targeting for antitumor drug delivery: a new SN-38-hyaluronan bioconjugate for locoregional treatment of peritoneal carcinomatosis

21 January 2018

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Anti-CD44 monoclonal antibody (IM7) induces murine systemic shock mediated by platelet activating factor

21 January 2018

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Preclinical evaluation of 89Zr-labeled anti-CD44 monoclonal antibody RG7356 in mice and cynomolgus monkeys: Prelude to Phase 1 clinical studies

21 January 2018

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CD133-targeted paclitaxel delivery inhibits local tumor recurrence in a mouse model of breast cancer

21 January 2018

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Targeting CD133 in an in vivo ovarian cancer model reduces ovarian cancer progression

21 January 2018

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CD133/prominin-1 is a potential therapeutic target for antibody-drug conjugates in hepatocellular and gastric cancers

21 January 2018

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In vitro and in vivo pharmacology and pharmacokinetics of a human engineered monoclonal antibody to epithelial cell adhesion molecule

21 January 2018

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Dysregulation of cellular signaling in gastric cancer

21 January 2018

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The Wnt/beta-catenin pathway regulates growth and maintenance of colonospheres

21 January 2018

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Targeting Wnt signaling: can we safely eradicate cancer stem cells?

21 January 2018

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Roles of Wnt/β-catenin signaling in the gastric cancer stem cells proliferation and salinomycin treatment

21 January 2018

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Chimeric 5/35 adenovirus-mediated Dickkopf-1 overexpression suppressed tumorigenicity of CD44⁺ gastric cancer cells via attenuating Wnt signaling.

21 January 2018

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Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours

21 January 2018

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Sonic Hedgehog Pathway Is Essential for Maintenance of Cancer Stem-Like Cells in Human Gastric Cancer

21 January 2018

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Notch signaling in stomach epithelial stem cell homeostasis

21 January 2018

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The activated Notch1 signal pathway is associated with gastric cancer progression through cyclooxygenase-2.

21 January 2018

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Notch inhibition as a promising new approach to cancer therapy

21 January 2018

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Colon cancer stem cells--from basic to clinical application

21 January 2018

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Pancreatic cancer stem cells: new insight into a stubborn disease

21 January 2018

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Cancer stem cells and their implication in breast cancer.

21 January 2018

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Glioblastoma stem-like cells: at the root of tumor recurrence and a therapeutic target.

21 January 2018

1 reference

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Lung cancer stem cells: progress and prospects

21 January 2018

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Melanocytes, melanocyte stem cells, and melanoma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Searching for prostate cancer stem cells: markers and methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

CD133 is a marker of gland‐forming cells in gastric tumors and Sox17 is involved in its regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Proteomic analysis of CD44(+) and CD44(-) gastric cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expression of cell adhesion molecule CD44 in gastric adenocarcinoma and its prognostic importance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expressions and clinical significances of CD133 protein and CD133 mRNA in primary lesion of gastric adenocacinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Aberrant expression of CD133 protein correlates with Ki-67 expression and is a prognostic marker in gastric adenocarcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expression of CD133 in the cytoplasm is associated with cancer progression and poor prognosis in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expressions of putative cancer stem cell markers ABCB1, ABCG2, and CD133 are correlated with the degree of differentiation of gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expression of CD44 variant 6 and lymphatic invasion: importance to lymph node metastasis in gastric cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

CD44 variant 9 expression in primary early gastric cancer as a predictive marker for recurrence.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

CD44/CD24 expression in recurrent gastric cancer: a retrospective analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

CD44(+) CD324(-) expression and prognosis in gastric cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expression of CD44 and Its Clinical Implication in Diffuse–Type and Intestinal–Type Gastric Adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00535-015-1125-5

Expression and prognostic value of the CD44 splicing variants v5 and v6 in gastric cancer

21 January 2018

1 reference

12 December 2020

Expression of CD44v6 in advanced gastric cancer and its relationship to hematogenous metastasis and long-term prognosis

1 reference

12 December 2020

CD133: to be or not to be, is this the real question?

1 reference

12 December 2020

HER2 status and benefit from adjuvant trastuzumab in breast cancer

1 reference

12 December 2020

Tumor growth need not be driven by rare cancer stem cells

1 reference

12 December 2020

CD54 expression is predictive for lymphatic spread in human gastric carcinoma

1 reference

12 December 2020

Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer

1 reference

12 December 2020

Expression of heparanase gene, CD44v6, MMP-7 and nm23 protein and their relationship with the invasion and metastasis of gastric carcinomas.

1 reference

12 December 2020

Cancer Stem Cell Markers CD44, CD133 in Primary Gastric Adenocarcinoma

1 reference

12 December 2020

CD44 Variant 9 Serves as a Poor Prognostic Marker in Early Gastric Cancer, But Not in Advanced Gastric Cancer

1 reference

12 December 2020

Tumor initiating potential of side population cells in human gastric cancer.

1 reference

12 December 2020

Expression of CD44 containing variant exon 9 (CD44v9) in gastric adenomas and adenocarcinomas: relation to the proliferation and progression

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12 December 2020

Combination of epithelial-mesenchymal transition and cancer stem cell-like phenotypes has independent prognostic value in gastric cancer

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12 December 2020

CD133 expression is correlated with chemoresistance and early recurrence of gastric cancer

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12 December 2020

CD44V6 in gastric carcinoma: a marker of tumor progression

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12 December 2020

Cytoplasmic CD24 Expression Is a Novel Prognostic Factor in Diffuse-Type Gastric Adenocarcinoma

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12 December 2020

Expression of the SRY-related HMG box protein SOX2 in human gastric carcinoma

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12 December 2020

CD44v8-10 is a cancer-specific marker for gastric cancer stem cells

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12 December 2020

Molecular biology. Cancer's perpetual source?

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12 December 2020

Gastric cancer stem-like cells possess higher capability of invasion and metastasis in association with a mesenchymal transition phenotype

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12 December 2020

Expression of cancer stem cell markers ALDH1, CD44 and CD133 in primary tumor and lymph node metastasis of gastric cancer

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12 December 2020

The Wnt/β-catenin pathway regulates self-renewal of cancer stem-like cells in human gastric cancer

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12 December 2020

Identification of a cancer stem cell in human brain tumors

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12 December 2020

Gastric cancer originating from bone marrow-derived cells

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12 December 2020

Role of cancer stem cell marker CD44 in gastric cancer: a meta-analysis

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12 December 2020

Spheroid body-forming cells in the human gastric cancer cell line MKN-45 possess cancer stem cell properties

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12 December 2020

Aldehyde dehydrogenase high gastric cancer stem cells are resistant to chemotherapy

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12 December 2020

Overexpression of CD133 enhances chemoresistance to 5-fluorouracil by activating the PI3K/Akt/p70S6K pathway in gastric cancer cells

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12 December 2020

Cancer spheres from gastric cancer patients provide an ideal model system for cancer stem cell research

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12 December 2020

Phase IB study of the EpCAM antibody adecatumumab combined with docetaxel in patients with EpCAM-positive relapsed or refractory advanced-stage breast cancer

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12 December 2020

CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer.

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12 December 2020

AC133, a novel marker for human hematopoietic stem and progenitor cells

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12 December 2020

Prognostic value of SOX2 in digestive tumors: a meta-analysis

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12 December 2020

Role of Notch signaling pathway in gastric cancer pathogenesis

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12 December 2020

Stem cell-like circulating tumor cells indicate poor prognosis in gastric cancer

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12 December 2020

Distinct types of tumor-initiating cells form human colon cancer tumors and metastases

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12 December 2020