New insights into the integrated physiology of insulin action (Q35711985)

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scientific article published on May 2004

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English	New insights into the integrated physiology of insulin action	scientific article published on May 2004

Statements

instance of

scholarly article

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

review article

1 reference

stated in

Europe PubMed Central

title

New insights into the integrated physiology of insulin action (English)

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

main subject

preproinsulin

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based on heuristic

inferred from title

physiology

0 references

author

Domenico Accili

series ordinal

2

object named as

Domenico Accili

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

author name string

Yukari Kitamura

series ordinal

1

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

publication date

1 May 2004

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

published in

Reviews in Endocrine and Metabolic Disorders

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

volume

5

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stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

issue

2

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

page(s)

143-149

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Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

cites work

Insulin: new roles for an ancient hormone

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insights into insulin resistance and type 2 diabetes from knockout mouse models

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Roles of insulin receptor substrate-1, phosphatidylinositol 3-kinase, and release of intracellular Ca2+ stores in insulin-stimulated insulin secretion in beta -cells.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetics of type 2 diabetes: insight from targeted mouse mutants

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective insulin signaling through A and B insulin receptors regulates transcription of insulin and glucokinase genes in pancreatic beta cells

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mosaic analysis of insulin receptor function

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise modulates postreceptor insulin signaling and glucose transport in muscle-specific insulin receptor knockout mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

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inferred from PubMed ID database lookup

Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

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inferred from PubMed ID database lookup

Impaired glucose transport as a cause of decreased insulin-stimulated muscle glycogen synthesis in type 2 diabetes

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Attenuation of insulin secretion by insulin-like growth factor 1 is mediated through activation of phosphodiesterase 3B.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Muscle-specific Pparg deletion causes insulin resistance

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A link between insulin resistance and hyperinsulinemia: inhibitors of phosphatidylinositol 3-kinase augment glucose-induced insulin secretion from islets of lean, but not obese, rats.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo mutagenesis of the insulin receptor

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of beta-cell mass in the growing rat pancreas. Estimation with a simple mathematical model.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Searching for type 2 diabetes genes in the post-genome era.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

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inferred from PubMed ID database lookup

Insulin-like growth factor-I at physiological concentrations is a potent inhibitor of insulin secretion

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinase in the life of the beta cell

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase suppresses glucose-stimulated insulin secretion by affecting post-cytosolic [Ca(2+)] elevation signals

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose tissue selective insulin receptor knockout protects against obesity and obesity-related glucose intolerance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of IRS-2 causes type 2 diabetes in mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of non-insulin-dependent diabetes mellitus in the double knockout mice with disruption of insulin receptor substrate-1 and beta cell glucokinase genes. Genetic reconstitution of diabetes as a polygenic disease

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased IGFR activity and glucose transport in cultured skeletal muscle from insulin receptor null mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a circulating islet cell growth factor in insulin-resistant states

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exercise and insulin cause GLUT-4 translocation in human skeletal muscle

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Exocytosis of insulin promotes insulin gene transcription via the insulin receptor/PI-3 kinase/p70 s6 kinase and CaM kinase pathways

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor-related receptor is expressed in pancreatic beta-cells and stimulates tyrosine phosphorylation of insulin receptor substrate-1 and -2.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue-specific knockout of the insulin receptor in pancreatic beta cells creates an insulin secretory defect similar to that in type 2 diabetes.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

What if Minkowski had been ageusic? An alternative angle on diabetes

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin receptor knockout mice

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired glucose tolerance in mice with a targeted impairment of insulin action in muscle and adipose tissue

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted expression of placental lactogen in the beta cells of transgenic mice results in beta cell proliferation, islet mass augmentation, and hypoglycemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted inactivation of the insulin receptor gene in mouse 3T3-L1 fibroblasts via homologous recombination

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

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12 December 2020

based on heuristic

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Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular mechanisms of insulin resistance and the role of the adipocyte

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preserved pancreatic beta-cell development and function in mice lacking the insulin receptor-related receptor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired insulin signaling in skeletal muscles from transgenic mice expressing kinase-deficient insulin receptors

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the glucose transporter 4 selectively in muscle causes insulin resistance and glucose intolerance.

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/15041790

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1023/B:REMD.0000021436.91347.93

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

Dimensions Publication ID

1003729508

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Fatcat ID

release_4dfnb3d3vfhm3b7es32zwi6ywu

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Fatcat

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https://api.fatcat.wiki/v0/release/4dfnb3d3vfhm3b7es32zwi6ywu

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24 November 2022

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mapped directly with Wikidata item

PubMed publication ID

15041790

1 reference

stated in

Europe PubMed Central

PubMed publication ID

15041790

retrieved

9 August 2017

 

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