Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins (Q35664126)

9 August 2017

title

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins (English)

1 reference

9 August 2017

0 references

Amanda J Ward

0 references

Jimena Giudice

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Eric T Wang

1 reference

9 August 2017

Jennifer M Cherone

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9 August 2017

Thomas T Wang

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9 August 2017

Daniel J Treacy

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9 August 2017

Nicole J Lambert

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9 August 2017

Peter Freese

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9 August 2017

Tanvi Saxena

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9 August 2017

Thomas A Cooper

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9 August 2017

Christopher B Burge

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9 August 2017

language of work or name

1 reference

16 April 2015

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9 August 2017

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

858-871

1 reference

A global regulatory mechanism for activating an exon network required for neurogenesis

9 August 2017

cites work

1 reference

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12 July 2018

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Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development

12 July 2018

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12 July 2018

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The Mef2 transcription network is disrupted in myotonic dystrophy heart tissue, dramatically altering miRNA and mRNA expression

12 July 2018

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12 July 2018

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CELFish ways to modulate mRNA decay

12 July 2018

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CUG-BP, Elav-like family (CELF)-mediated alternative splicing regulation in the brain during health and disease.

12 July 2018

1 reference

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Transcriptome-wide regulation of pre-mRNA splicing and mRNA localization by muscleblind proteins

12 July 2018

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CUGBP1 and MBNL1 preferentially bind to 3' UTRs and facilitate mRNA decay

12 July 2018

1 reference

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The importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteins

12 July 2018

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Analysis and design of RNA sequencing experiments for identifying isoform regulation

12 July 2018

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SOBP is mutated in syndromic and nonsyndromic intellectual disability and is highly expressed in the brain limbic system

12 July 2018

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CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.

12 July 2018

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Systematic analysis of cis-elements in unstable mRNAs demonstrates that CUGBP1 is a key regulator of mRNA decay in muscle cells

12 July 2018

1 reference

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Analysis of CUGBP1 targets identifies GU-repeat sequences that mediate rapid mRNA decay

12 July 2018

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MicroRNAs coordinate an alternative splicing network during mouse postnatal heart development

12 July 2018

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A scaling normalization method for differential expression analysis of RNA-seq data

12 July 2018

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Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.

12 July 2018

1 reference

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MBNL1 binds GC motifs embedded in pyrimidines to regulate alternative splicing

12 July 2018

1 reference

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Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.

12 July 2018

1 reference

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Engineering splicing factors with designed specificities

12 July 2018

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Splice site strength-dependent activity and genetic buffering by poly-G runs

12 July 2018

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The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulation

12 July 2018

1 reference

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CUGBP2 directly interacts with U2 17S snRNP components and promotes U2 snRNA binding to cardiac troponin T pre-mRNA.

12 July 2018

1 reference

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Progressive lengthening of 3' untranslated regions of mRNAs by alternative polyadenylation during mouse embryonic development.

12 July 2018

1 reference

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TopHat: discovering splice junctions with RNA-Seq

12 July 2018

1 reference

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CLIP: construction of cDNA libraries for high-throughput sequencing from RNAs cross-linked to proteins in vivo

12 July 2018

1 reference

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12 July 2018

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A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

12 July 2018

1 reference

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Posttranscriptional regulation of gene networks by GU-rich elements and CELF proteins

12 July 2018

1 reference

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Conserved GU-rich elements mediate mRNA decay by binding to CUG-binding protein 1

12 July 2018

1 reference

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Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing

12 July 2018

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Correction of ClC-1 splicing eliminates chloride channelopathy and myotonia in mouse models of myotonic dystrophy

12 July 2018

1 reference

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Increased steady-state levels of CUGBP1 in myotonic dystrophy 1 are due to PKC-mediated hyperphosphorylation

12 July 2018

1 reference

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CUG-BP1/CELF1 requires UGU-rich sequences for high-affinity binding

12 July 2018

1 reference

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Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy

12 July 2018

1 reference

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Mammalian CELF/Bruno-like RNA-binding proteins: molecular characteristics and biological functions

12 July 2018

1 reference

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RNA-dependent integrin alpha3 protein localization regulated by the Muscleblind-like protein MLP1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Polypyrimidine tract binding protein blocks the 5' splice site-dependent assembly of U2AF and the prespliceosomal E complex

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Regulation of Fas alternative splicing by antagonistic effects of TIA-1 and PTB on exon definition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Colocalization of muscleblind with RNA foci is separable from mis-regulation of alternative splicing in myotonic dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Understanding alternative splicing: towards a cellular code

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Identification of CELF splicing activation and repression domains in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Dynamic balance between activation and repression regulates pre-mRNA alternative splicing during heart development

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Identification of putative new splicing targets for ETR-3 using sequences identified by systematic evolution of ligands by exponential enrichment

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Muscleblind proteins regulate alternative splicing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

A functional deadenylation assay identifies human CUG-BP as a deadenylation factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Expanded CUG repeats trigger aberrant splicing of ClC-1 chloride channel pre-mRNA and hyperexcitability of skeletal muscle in myotonic dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

KCNJ2 mutation results in Andersen syndrome with sex-specific cardiac and skeletal muscle phenotypes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Novel proteins with binding specificity for DNA CTG repeats and RNA CUG repeats: implications for myotonic dystrophy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

A quantitative analysis of CLIP methods for identifying binding sites of RNA-binding proteins

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Overexpression of MBNL1 fetal isoforms and modified splicing of Tau in the DM1 brain: two individual consequences of CUG trinucleotide repeats.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Inducible-NOS but not neuronal-NOS participate in the acute effect of TNF-alpha on hypothalamic insulin-dependent inhibition of food intake

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Overexpression of CUG triplet repeat-binding protein, CUGBP1, in mice inhibits myogenesis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4448682

Dynamic antagonism between ETR-3 and PTB regulates cell type-specific alternative splicing

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25883322

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GR.184390.114

1 reference

9 August 2017

1 reference

9 August 2017

1 reference