Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation (Q35657838)

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scientific article published on 12 December 2011

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English	Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation	scientific article published on 12 December 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

9 August 2017

Reverse signaling through the costimulatory ligand CD137L in epithelial cells is essential for natural killer cell-mediated acute tissue inflammation (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

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author name string

Hye J Kim

1

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Europe PubMed Central

PubMed publication ID

9 August 2017

Jong S Lee

2

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PubMed publication ID

9 August 2017

Jung D Kim

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Hee J Cha

4

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PubMed publication ID

9 August 2017

Ahra Kim

5

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Europe PubMed Central

PubMed publication ID

9 August 2017

Sun K Lee

6

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Europe PubMed Central

PubMed publication ID

9 August 2017

Sang C Lee

7

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Europe PubMed Central

PubMed publication ID

9 August 2017

Byoung S Kwon

8

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Robert S Mittler

9

1 reference

Europe PubMed Central

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9 August 2017

Hong R Cho

10

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9 August 2017

Byungsuk Kwon

11

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Europe PubMed Central

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9 August 2017

language of work or name

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publication date

12 December 2011

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Europe PubMed Central

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9 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

PubMed publication ID

9 August 2017

109

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Europe PubMed Central

PubMed publication ID

9 August 2017

1

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Europe PubMed Central

PubMed publication ID

9 August 2017

E13-22

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Europe PubMed Central

PubMed publication ID

9 August 2017

Epithelial decision makers: in search of the 'epimmunome'.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

CD137 ligand, a member of the tumor necrosis factor family, regulates immune responses via reverse signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

CD137-CD137 Ligand Interactions in Inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Regulatory NK-cell functions in inflammation and autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

The role of TNF superfamily members in T-cell function and diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

4-1BB functions as a survival factor in dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Chemokine/chemokine receptor-mediated inflammation regulates pathologic changes from acute kidney injury to chronic kidney disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

NK cells induce apoptosis in tubular epithelial cells and contribute to renal ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

The innate immune response in ischemic acute kidney injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Origin and physiological roles of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Identification of regulatory functions for 4-1BB and 4-1BBL in myelopoiesis and the development of dendritic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Functions of natural killer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

A calculated response: control of inflammation by the innate immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

TLR4 activation mediates kidney ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Cell surface 4-1BBL mediates sequential signaling pathways 'downstream' of TLR and is required for sustained TNF production in macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

New cellular and molecular immune pathways in ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

CD137-mediated immunotherapy for allergic asthma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Costimulation of mast cells by 4-1BB, a member of the tumor necrosis factor receptor superfamily, with the high-affinity IgE receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Inflammation and the reciprocal production of granulocytes and lymphocytes in bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

CD137-deficient mice have reduced NK/NKT cell numbers and function, are resistant to lipopolysaccharide-induced shock syndromes, and have lower IL-4 responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Recent advances in the pathophysiology of ischemic acute renal failure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

CD137 costimulatory T cell receptor engagement reverses acute disease in lupus-prone NZB x NZW F1 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Points of control in inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Neutralization of Gro alpha and macrophage inflammatory protein-2 attenuates renal ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Is the proximal tubular cell a proinflammatory cell?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Possible role for CD40-CD40L in the regulation of interstitial infiltration in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

12 July 2018

Osteopontin expressed in tubular epithelial cells regulates NK cell-mediated kidney ischemia reperfusion injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

CD137 (4-1BB) deficiency reduces atherosclerosis in hyperlipidemic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Attenuation of experimental autoimmune myocarditis by blocking T cell activation through 4-1BB pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Induction of lethal graft-versus-host disease by anti-CD137 monoclonal antibody in mice prone to chronic graft-versus-host disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Costimulatory molecule-targeted immunotherapy of cutaneous graft-versus-host disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Keratinocyte-derived chemokine is an early biomarker of ischemic acute kidney injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Inhibition of the chemokine receptor CXCR2 prevents kidney graft function deterioration due to ischemia/reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

4-1BB-mediated immunotherapy of rheumatoid arthritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Blocking 4-1BB/4-1BB ligand interactions prevents herpetic stromal keratitis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Immune responses in 4-1BB (CD137)-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Functional CD137 receptors are expressed by eosinophils from patients with IgE-mediated allergic responses but not by eosinophils from patients with non-IgE-mediated eosinophilic disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Apoptosis and chemokine induction after renal ischemia-reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

Analysis of 4-1BB ligand (4-1BBL)-deficient mice and of mice lacking both 4-1BBL and CD28 reveals a role for 4-1BBL in skin allograft rejection and in the cytotoxic T cell response to influenza virus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3252952

25 September 2018

CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD137 activation abrogates granulocyte-macrophage colony-stimulating factor-mediated anti-apoptosis in neutrophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD137 ligand reverse signaling has multiple functions in human dendritic cells during an adaptive immune response

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of agonistic anti-4-1BB monoclonal antibody leads to the amelioration of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation with 4-1BB (CD137) inhibits chronic graft-versus-host disease by inducing activation-induced cell death of donor CD4+ T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Introduction of stable high-copy-number DNA into Chinese hamster ovary cells by electroporation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

4-1BB engagement costimulates NKT cell activation and exacerbates NKT cell ligand-induced airway hyperresponsiveness and inflammation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/22160719

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.1112256109

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

2012PNAS..109E..13K

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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