Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants (Q35605724)

9 August 2017

title

Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants (English)

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9 August 2017

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Dongxiao Sun

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9 August 2017

Gang Chen

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9 August 2017

Ryan W Dellinger

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9 August 2017

Kimberly Duncan

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9 August 2017

Jia-Long Fang

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9 August 2017

Philip Lazarus

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9 August 2017

publication date

1 January 2006

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9 August 2017

published in

Breast Cancer Research

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9 August 2017

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9 August 2017

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9 August 2017

page(s)

R50

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Extended adjuvant endocrine therapy of early breast cancer

9 August 2017

cites work

1 reference

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12 July 2018

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Quaternary ammonium-linked glucuronidation of trans-4-hydroxytamoxifen, an active metabolite of tamoxifen, by human liver microsomes and UDP-glucuronosyltransferase 1A4.

12 July 2018

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Quaternary ammonium-linked glucuronidation of tamoxifen by human liver microsomes and UDP-glucuronosyltransferase 1A4.

25 September 2018

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Pharmacological characterization of 4-hydroxy-N-desmethyl tamoxifen, a novel active metabolite of tamoxifen

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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25 September 2018

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N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog, and human liver microsomes

25 September 2018

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Tamoxifen therapy for breast cancer and endometrial cancer risk.

25 September 2018

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A general assay for UDPglucuronosyltransferase activity using polar amino-cyano stationary phase HPLC and UDP[U-14C]glucuronic acid.

25 September 2018

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Risk of endometrial cancer after tamoxifen treatment of breast cancer

25 September 2018

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Crossref

https://api.crossref.org/works/10.1186%2FBCR1539

Identification of 4-hydroxy-N-desmethyltamoxifen as a metabolite of tamoxifen in human bile

21 January 2018

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12 December 2020

Distribution of 4-hydroxy-N-desmethyltamoxifen and other tamoxifen metabolites in human biological fluids during tamoxifen treatment

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12 December 2020

Analysis of phase I and phase II metabolites of tamoxifen in breast cancer patients

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12 December 2020

Adjuvant tamoxifen therapy for early stage breast cancer and second primary malignancies. Stockholm Breast Cancer Study Group

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12 December 2020

Glucuronidation of amines and hydroxylated xenobiotics and endobiotics catalyzed by expressed human UGT1.4 protein

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12 December 2020

Glucuronidation of amine substrates by purified and expressed UDP-glucuronosyltransferase proteins

1 reference

12 December 2020

Tamoxifen in the treatment of breast cancer

1 reference

12 December 2020

Comparative N-glucuronidation kinetics of ketotifen and amitriptyline by expressed human UDP-glucuronosyltransferases and liver microsomes

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12 December 2020

Identifiers

DOI

10.1186/BCR1539

1 reference

Dimensions Publication ID

9 August 2017

0 references

1 reference

9 August 2017

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