Mg(2+) binding to open and closed states can activate BK channels provided that the voltage sensors are elevated (Q35581373)

9 August 2017

title

Mg(2+) binding to open and closed states can activate BK channels provided that the voltage sensors are elevated (English)

1 reference

9 August 2017

Ren-Shiang Chen

1 reference

9 August 2017

Yanyan Geng

series ordinal

1 reference

9 August 2017

Karl L Magleby

series ordinal

1 reference

9 August 2017

publication date

1 December 2011

1 reference

The Journal of General Physiology

9 August 2017

published in

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9 August 2017

volume

138

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9 August 2017

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9 August 2017

page(s)

593-607

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Metal-driven operation of the human large-conductance voltage- and Ca2+-dependent potassium channel (BK) gating ring apparatus.

9 August 2017

cites work

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BK-type calcium-activated potassium channels: coupling of metal ions and voltage sensing

12 July 2018

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An epilepsy/dyskinesia-associated mutation enhances BK channel activation by potentiating Ca2+ sensing

12 July 2018

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Allosteric interactions and the modular nature of the voltage- and Ca2+-activated (BK) channel

12 July 2018

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Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel

12 July 2018

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Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution

12 July 2018

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Measurements of the BKCa channel's high-affinity Ca2+ binding constants: effects of membrane voltage

12 July 2018

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Activation of Slo1 BK channels by Mg2+ coordinated between the voltage sensor and RCK1 domains

12 July 2018

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Mg2+ enhances voltage sensor/gate coupling in BK channels

12 July 2018

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Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channels

12 July 2018

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12 July 2018

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12 July 2018

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Ring of negative charge in BK channels facilitates block by intracellular Mg2+ and polyamines through electrostatics

12 July 2018

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12 July 2018

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Intracellular Mg2+ influences both open and closed times of a native Ca2+-activated BK channel in cultured human renal proximal tubule cells

12 July 2018

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12 July 2018

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Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

12 July 2018

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Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites.

12 July 2018

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Linker-gating ring complex as passive spring and Ca(2+)-dependent machine for a voltage- and Ca(2+)-activated potassium channel

12 July 2018

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Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels

12 July 2018

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Beta1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms

12 July 2018

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A ring of eight conserved negatively charged amino acids doubles the conductance of BK channels and prevents inward rectification

12 July 2018

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12 July 2018

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Coupling between voltage sensor activation, Ca2+ binding and channel opening in large conductance (BK) potassium channels

12 July 2018

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Elimination of the BK(Ca) channel's high-affinity Ca(2+) sensitivity

12 July 2018

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Crystal structure and mechanism of a calcium-gated potassium channel

12 July 2018

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Allosteric regulation of BK channel gating by Ca(2+) and Mg(2+) through a nonselective, low affinity divalent cation site

12 July 2018

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Intracellular Mg(2+) enhances the function of BK-type Ca(2+)-activated K(+) channels

12 July 2018

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Voltage and Ca2+ activation of single large-conductance Ca2+-activated K+ channels described by a two-tiered allosteric gating mechanism.

12 July 2018

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Functional coupling of the beta(1) subunit to the large conductance Ca(2+)-activated K(+) channel in the absence of Ca(2+). Increased Ca(2+) sensitivity from a Ca(2+)-independent mechanism

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Calcium-activated potassium channels

12 July 2018

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Large conductance voltage- and calcium-dependent K + channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus

12 July 2018

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A novel calcium-sensing domain in the BK channel

12 July 2018

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Intrinsic voltage dependence and Ca2+ regulation of mslo large conductance Ca-activated K+ channels

12 July 2018

1 reference

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Contribution of the S4 segment to gating charge in the Shaker K+ channel.

12 July 2018

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mSlo , a Complex Mouse Gene Encoding "Maxi" Calcium-Activated Potassium Channels

12 July 2018

1 reference

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Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

12 July 2018

1 reference

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Kinetic states and modes of single large-conductance calcium-activated potassium channels in cultured rat skeletal muscle

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Activation by divalent cations of a Ca2+-activated K+ channel from skeletal muscle membrane

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Sampling, log binning, fitting, and plotting durations of open and shut intervals from single channels and the effects of noise

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Allosteric effects of Mg2+ on the gating of Ca2+-activated K+ channels from mammalian skeletal muscle.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Mechanisms of magnesium transport

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Competitive Mg2+ block of a large-conductance, Ca(2+)-activated K+ channel in rat skeletal muscle. Ca2+, Sr2+, and Ni2+ also block

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

A Component of Calcium-activated Potassium Channels Encoded by the Drosophila slo Locus

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

New insights into the structure and function of potassium channels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Ion effects on gating of the Ca(2+)-activated K+ channel correlate with occupancy of the pore

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Calcium-activated potassium channels expressed from cloned complementary DNAs

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Mg2+-dependent regulation of BK channels: importance of electrostatics.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Multiple regulatory sites in large-conductance calcium-activated potassium channels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Mechanism of magnesium activation of calcium-activated potassium channels.

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Tetraethylammonium block of Slowpoke calcium-activated potassium channels expressed in Xenopus oocytes: evidence for tetrameric channel formation

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3226971

Ca-dependent K channels with large unitary conductance in chromaffin cell membranes

26 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1085%2FJGP.201110707

Single channel recordings of Ca2+-activated K+ currents in rat muscle cell culture

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1085%2FJGP.201110707

Lithium induced changes in intracellular free magnesium concentration in isolated rat ventricular myocytes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22124117

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Calcium dependence of open and shut interval distributions from calcium-activated potassium channels in cultured rat muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22124117

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Burst kinetics of single calcium-activated potassium channels in cultured rat muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22124117

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1085/JGP.201110707

1 reference

9 August 2017

1 reference

9 August 2017

1 reference