Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers. (Q35584967)

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scientific article published on 31 May 2011

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English	Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers.	scientific article published on 31 May 2011

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scholarly article

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Europe PubMed Central

PMC publication ID

3228218

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

title

Early clinical development of ARQ 197, a selective, non-ATP-competitive inhibitor targeting MET tyrosine kinase for the treatment of advanced cancers (English)

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

author

Brian Schwartz

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2

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Europe PubMed Central

PMC publication ID

3228218

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

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2 February 2020

Alex A Adjei

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1

object named as

Alex A Adjei

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

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2 February 2020

author name string

Edward Garmey

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3

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

publication date

31 May 2011

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stated in

Europe PubMed Central

PMC publication ID

3228218

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

published in

Oncologist

1 reference

stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

volume

16

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

issue

6

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

page(s)

788-799

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stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

cites work

MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor

1 reference

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PubMed Central

reference URL

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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27 July 2018

Discovery of small molecule c-Met inhibitors: Evolution and profiles of clinical candidates

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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27 July 2018

Single-agent and combination therapeutic strategies to inhibit hepatocyte growth factor/MET signaling in cancer

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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27 July 2018

MET as a target for treatment of chest tumors

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PubMed Central

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27 July 2018

Drug development of MET inhibitors: targeting oncogene addiction and expedience

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PubMed Central

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27 July 2018

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

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27 July 2018

c-Met as a target for human cancer and characterization of inhibitors for therapeutic intervention

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27 July 2018

Met, metastasis, motility and more

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PubMed Central

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27 July 2018

HGF/SF-met signaling in the control of branching morphogenesis and invasion

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27 July 2018

Met receptor tyrosine kinase: enhanced signaling through adapter proteins

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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27 July 2018

A novel germ line juxtamembrane Met mutation in human gastric cancer

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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27 July 2018

Hepatocyte growth factor/scatter factor, its molecular, cellular and clinical implications in cancer

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27 July 2018

Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinase

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27 July 2018

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

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27 July 2018

ARQ 197, a novel and selective inhibitor of the human c-Met receptor tyrosine kinase with antitumor activity.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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26 September 2018

MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

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PubMed Central

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26 September 2018

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma.

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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26 September 2018

Absence of tpr-met and expression of c-met in human gastric mucosa and carcinoma.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3228218

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26 September 2018

Antagonistic effect of NK4, a novel hepatocyte growth factor variant, on in vitro angiogenesis of human vascular endothelial cells

1 reference

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21632449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoblot analysis of c-Met expression in human colorectal cancer: overexpression is associated with advanced stage cancer

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/21632449

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1634/THEONCOLOGIST.2010-0380

1 reference

stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

PMC publication ID

3228218

1 reference

stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

PubMed publication ID

21632449

1 reference

stated in

Europe PubMed Central

PMC publication ID

3228218

reference URL

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21632449%20AND%20SRC:MED&resulttype=core&format=json

retrieved

2 February 2020

ResearchGate publication ID

51183754

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