Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin (Q35505126)

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scientific article published on 21 April 2015

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English	Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin	scientific article published on 21 April 2015

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PubMed publication ID

8 August 2017

Therapeutic targeting of CBP/β-catenin signaling reduces cancer stem-like population and synergistically suppresses growth of EBV-positive nasopharyngeal carcinoma cells with cisplatin (English)

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8 August 2017

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Joseph Chok Yan Ip

3

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10 June 2020

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King Chi Chan

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Lai Sheung Chan

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Carman Lo

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Timothy Tak Chun Yip

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Roger Kai Cheong Ngan

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Kwok Wai Lo

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Anne Wing Mui Lee

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George Sai Wah Tsao

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Michael Kahn

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Nai Ki Mak

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21 April 2015

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Scientific Reports

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10 June 2020

9979

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10 June 2020

Can we safely target the WNT pathway?

1 reference

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12 July 2018

Safely targeting cancer stem cells via selective catenin coactivator antagonism

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12 July 2018

Etiological factors of nasopharyngeal carcinoma

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12 July 2018

A novel Hsp90 inhibitor AT13387 induces senescence in EBV-positive nasopharyngeal carcinoma cells and suppresses tumor formation

1 reference

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12 July 2018

Physiological β-catenin signaling controls self-renewal networks and generation of stem-like cells from nasopharyngeal carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4404684

12 July 2018

Epstein-Barr virus induction of the Hedgehog signalling pathway imposes a stem cell phenotype on human epithelial cells

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12 July 2018

Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway.

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12 July 2018

Wnt/β-catenin signalling induces MLL to create epigenetic changes in salivary gland tumours

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Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia

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12 July 2018

CD44+ cancer stem-like cells in EBV-associated nasopharyngeal carcinoma.

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12 July 2018

An orthotopic model of metastatic nasopharyngeal carcinoma and its application in elucidating a therapeutic target that inhibits metastasis

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12 July 2018

Adenovirus-mediated RNA interference targeting FOXM1 transcription factor suppresses cell proliferation and tumor growth of nasopharyngeal carcinoma

1 reference

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12 July 2018

Role of STAT3/5 and Bcl-2/xL in 2-methoxyestradiol-induced endoreduplication of nasopharyngeal carcinoma cells

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12 July 2018

EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin.

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12 July 2018

Eyes wide open: a critical review of sphere-formation as an assay for stem cells

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12 July 2018

Cancer stem cell subsets and their relationships

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FoxM1 in tumorigenicity of the neuroblastoma cells and renewal of the neural progenitors

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Role of Hyaluronan-Mediated CD44 Signaling in Head and Neck Squamous Cell Carcinoma Progression and Chemoresistance

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12 July 2018

Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways

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12 July 2018

Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis

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12 July 2018

The Wnt signaling pathway in cellular proliferation and differentiation: A tale of two coactivators

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12 July 2018

Epigenetic Alteration of the Wnt Inhibitory Factor-1 Promoter Is Common and Occurs in Advanced Stage of Tunisian Nasopharyngeal Carcinoma

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12 July 2018

Targeting Wnt signaling: can we safely eradicate cancer stem cells?

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12 July 2018

Nasopharyngeal carcinoma: the next challenges

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Small molecules and stem cells. Potency and lineage commitment: the new quest for the fountain of youth

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12 July 2018

Preclinical activity of gefitinib in non-keratinizing nasopharyngeal carcinoma cell lines and biomarkers of response

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Abate and switch: miR-145 in stem cell differentiation.

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MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells

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MicroRNA deregulation and pathway alterations in nasopharyngeal carcinoma

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Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits

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Cancer stem cells in solid tumors: an overview

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MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

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Identification of cancer stem cell-like side population cells in human nasopharyngeal carcinoma cell line

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The tumor suppressor Wnt inhibitory factor 1 is frequently methylated in nasopharyngeal and esophageal carcinomas.

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Gene expression profiling of nasopharyngeal carcinoma reveals the abnormally regulated Wnt signaling pathway

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Focus on nasopharyngeal carcinoma

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Nasopharyngeal carcinoma cell line (C666-1) consistently harbouring Epstein-Barr virus

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Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas

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Aberrant expression of β-catenin and E-cadherin is correlated with poor prognosis of nasopharyngeal cancer

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Nasopharyngeal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25897700

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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Expression and clinical significance of Wnt-1 and beta-catenin in nasopharyngeal carcinoma

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10.1038/SREP09979

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10 June 2020

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10 June 2020

PubMed publication ID

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10 June 2020

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