Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man. (Q35457110)

8 August 2017

1 reference

title

Excitatory amino acid antagonists and their potential for the treatment of ischaemic brain damage in man. (English)

1 reference

8 August 2017

J McCulloch

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8 August 2017

language of work or name

English

0 references

publication date

1 August 1992

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British Journal of Clinical Pharmacology

8 August 2017

published in

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

106-114

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8 August 2017

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Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia

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Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil.

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Protective effect of the glutamate antagonist, MK-801 in focal cerebral ischemia in the cat.

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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The neuroprotective actions of kynurenic acid and MK-801 in gerbils are synergistic and not related to hypothermia

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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Selective blockade of N-methyl-D-aspartate (NMDA)-induced convulsions by NMDA antagonists and putative glycine antagonists: relationship with phencyclidine-like behavioral effects

12 July 2018

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Enantiomers of HA-966 (3-amino-1-hydroxypyrrolid-2-one) exhibit distinct central nervous system effects: (+)-HA-966 is a selective glycine/N-methyl-D-aspartate receptor antagonist, but (-)-HA-966 is a potent gamma-butyrolactone-like sedative

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Pre- and post-treatment with MK-801 but not pretreatment alone reduces neocortical damage after focal cerebral ischemia in the rat.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

The release and uptake of excitatory amino acids

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Reduction of infarct volume by magnesium after middle cerebral artery occlusion in rats

12 July 2018

1 reference

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Protection after transient focal cerebral ischemia by the N-methyl-D-aspartate antagonist dextrorphan is dependent upon plasma and brain levels

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

The effects of dizocilpine (MK-801), phencyclidine, and nimodipine on infarct size 48 h after middle cerebral artery occlusion in the rat.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

The neuroprotective action of dizocilpine (MK-801) in the rat middle cerebral artery occlusion model of focal ischaemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Evaluation of a competitive NMDA antagonist (D-CPPene) in feline focal cerebral ischemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Autoradiographic assessment of the effects of N-methyl-d-aspartate (NMDA) receptor antagonists in vivo

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Correlation of the extracellular glutamate concentration with extent of blood flow reduction after subdural hematoma in the rat.

12 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Blockade of the AMPA receptor prevents CA1 hippocampal injury following severe but transient forebrain ischemia in adult rats

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Autoradiographic analysis of 3H-MK-801 (dizocilpine) in vivo uptake and in vitro binding after focal cerebral ischemia in the rat

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Postischemic blockade of AMPA but not NMDA receptors mitigates neuronal damage in the rat brain following transient severe cerebral ischemia

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1381526

Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury

12 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04118.X

The neuroprotective actions of 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline (NBQX) in a rat focal ischaemia model

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04118.X

Thresholds of focal cerebral ischemia in awake monkeys

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04118.X

Effect of MK-801 on focal brain infarction in normotensive and hypertensive rats

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04118.X

The excitatory amino acid antagonist kynurenic acid administered after hypoxic-ischemia in neonatal rats offers neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.1992.TB04118.X

Effects of NMDA antagonists, MK-801 and CPP, upon local cerebral glucose use

21 January 2018

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12 December 2020

Ischemic flow threshold for extracellular glutamate increase in cat cortex

1 reference

12 December 2020

Evaluation of the glutamate antagonist dizocilipine maleate (MK-801) on neurologic outcome in a canine model of complete cerebral ischemia: correlation with hippocampal histopathology

1 reference

12 December 2020

Neuroprotective effects of MK-801, TCP, PCP and CPP against N-methyl-D-aspartate induced neurotoxicity in an in vivo perinatal rat model

1 reference

12 December 2020

Differential effects of competitive and non-competitive N-methyl-D-aspartate antagonists on glucose use in the limbic system

1 reference

12 December 2020

The glutamate antagonist MK-801 reduces focal ischemic brain damage in the rat

1 reference

12 December 2020

The influence of mild body and brain hypothermia on ischemic brain damage

1 reference

12 December 2020

Posthypoxic treatment with MK-801 reduces hypoxic-ischemic damage in the neonatal rat

1 reference

12 December 2020

Focal cerebral ischaemia in the cat: treatment with the glutamate antagonist MK-801 after induction of ischaemia

1 reference

12 December 2020

Hypothermia but not the N-methyl-D-aspartate antagonist, MK-801, attenuates neuronal damage in gerbils subjected to transient global ischemia

1 reference

12 December 2020

Ifenprodil and SL 82.0715 are antagonists at the polyamine site of the N-methyl-D-aspartate (NMDA) receptor

1 reference

12 December 2020

Combined therapy with MK-801 and nimodipine for protection of ischemic brain damage

1 reference

12 December 2020

10.1111/J.1365-2125.1992.TB04118.X

Identifiers

DOI

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8 August 2017

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8 August 2017

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