Characterization of a recombinant pneumolysin and its use as a protein carrier for pneumococcal type 18C conjugate vaccines (Q35424204)

8 August 2017

title

Characterization of a recombinant pneumolysin and its use as a protein carrier for pneumococcal type 18C conjugate vaccines (English)

1 reference

8 August 2017

Kuo J

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8 August 2017

Douglas M

series ordinal

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8 August 2017

Ree HK

series ordinal

1 reference

8 August 2017

Lindberg AA

series ordinal

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8 August 2017

language of work or name

English

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publication date

1 July 1995

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8 August 2017

published in

Infection and Immunity

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8 August 2017

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8 August 2017

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8 August 2017

page(s)

2706-2713

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Toxicity of pneumolysin to pulmonary alveolar epithelial cells

8 August 2017

cites work

1 reference

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Immunization of mice with pneumolysin toxoid confers a significant degree of protection against at least nine serotypes of Streptococcus pneumoniae

27 July 2018

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Effects of pneumolysin on human polymorphonuclear leukocytes and platelets

27 July 2018

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Some observations on the pneumococcus and on the current status of pneumococcal disease and its prevention.

27 July 2018

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Preparation, characterization, and immunogenicity of Haemophilus influenzae type b polysaccharide-protein conjugates

27 July 2018

1 reference

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Effect of immunization with pneumolysin on survival time of mice challenged with Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Immunochemistry of groups A, B, and C meningococcal polysaccharide-tetanus toxoid conjugates.

27 July 2018

1 reference

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Inhibition of in vitro human lymphocyte response by the pneumococcal toxin pneumolysin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Considerations for Formulating the Second-Generation Pneumococcal Capsular Polysaccharide Vaccine with Emphasis on the Cross-Reactive Types Within Groups

27 July 2018

1 reference

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Studies on transformation of Escherichia coli with plasmids

27 July 2018

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The direct coupling of oligosaccharides to proteins and derivatized gels

27 July 2018

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Properties of purified pneumococcal hemolysin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Production and purification of Streptococcus pneumoniae hemolysin (pneumolysin)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Effect of culture conditions on the structure of Streptococcus pneumoniae type 19A(57) capsular polysaccharide

27 July 2018

1 reference

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Molecular cloning, characterization, and complete nucleotide sequence of the gene for pneumolysin, the sulfhydryl-activated toxin of Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Serum antibodies to pneumolysin in patients with pneumonia

27 July 2018

1 reference

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Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Cloning and expression in Escherichia coli of the Streptococcus pneumoniae gene encoding pneumolysin

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Reduced virulence of a defined pneumolysin-negative mutant of Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Background and indications for Haemophilus influenzae type b vaccines consisting of capsular antigen coupled to protein carriers.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Carrier-induced epitopic suppression, a major issue for future synthetic vaccines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Duration of serum antibodies elicited by Haemophilus influenzae type b capsular polysaccharide alone or conjugated to tetanus toxoid in 18- to 23-month-old children

27 July 2018

1 reference

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A randomized, prospective field trial of a conjugate vaccine in the protection of infants and young children against invasive Haemophilus influenzae type b disease.

27 July 2018

1 reference

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Polysaccharide-protein conjugates: a new generation of vaccines

27 July 2018

1 reference

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Purification and immunogenicity of genetically obtained pneumolysin toxoids and their conjugation to Streptococcus pneumoniae type 19F polysaccharide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Effect of carrier priming on immunogenicity of saccharide-protein conjugate vaccines

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Pneumococcal proteins and the pathogenesis of disease caused by Streptococcus pneumoniae

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Toxicity of pneumolysin to pulmonary endothelial cells in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Plasmid vectors for the selection of promoters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=173362

Protection of infant mice from challenge with Streptococcus pneumoniae type 19F by immunization with a type 19F polysaccharide--pneumolysoid conjugate

26 September 2018

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12 December 2020

The derivatization of cross-linked polyacrylamide beads. Controlled introduction of functional groups for the preparation of special-purpose, biochemical adsorbents

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12 December 2020

Proteins containing reductively aminated disaccharides. Synthesis and chemical characterization

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A Simplified Procedure for Purification of Human Prothrombin, Factor IX and Factor X

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Antibody response to pneumococcal vaccination in children younger than five years of age

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Antibody response to 14-valent pneumococcal capsular polysaccharide vaccine in pre-school age children

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12 December 2020

Serum antibodies to pneumococcal C polysaccharide in children: response to acute pneumococcal otitis media or to vaccination

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12 December 2020

Production of pneumolysin, a pneumococcal toxin, in Bacillus subtilis

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12 December 2020

Measurement of antibody responses to pneumolysin--a promising method for the presumptive aetiological diagnosis of pneumococcal pneumonia

1 reference

12 December 2020

Immunogenicity of a Haemophilus influenzae polysaccharide-Neisseria meningitidis outer membrane protein complex conjugate vaccine

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A comparative study of the immunogenicity of pneumococcal type 4 polysaccharide and oligosaccharide tetanus toxoid conjugates in adult mice

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Pneumococcal conjugate vaccines

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Escherichia hermannii (ATCC 33651) polysaccharide-protein conjugates: comparison of two conjugation methods for the induction of humoral responses in mice

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Induction of antibody and protective responses in mice by Brucella O-polysaccharide-BSA conjugate

1 reference

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Effect of insertional inactivation of the genes encoding pneumolysin and autolysin on the virulence of Streptococcus pneumoniae type 3

1 reference

12 December 2020

Safety, immunogenicity, and efficacy in infancy of oligosaccharide conjugate Haemophilus influenzae type b vaccine in a United States population: possible implications for optimal use

1 reference

12 December 2020

10.1128/IAI.63.7.2706-2713.1995

Identifiers

DOI

0 references

PMC publication ID

173362

1 reference

8 August 2017

1 reference