Induction of interferon pathways mediates in vivo resistance to oncolytic adenovirus (Q35285768)

7 August 2017

title

Induction of interferon pathways mediates in vivo resistance to oncolytic adenovirus (English)

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7 August 2017

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Akseli Hemminki

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7 August 2017

Iulia Diaconu

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7 August 2017

Tanja Hakkarainen

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7 August 2017

Sophie Escutenaire

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7 August 2017

Anna Kanerva

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7 August 2017

Ilkka Liikanen

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7 August 2017

Sari Pesonen

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7 August 2017

Otto Hemminki

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7 August 2017

Vladia Monsurrò

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7 August 2017

Laura Ahtiainen

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7 August 2017

Mari Raki

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7 August 2017

João D Dias

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7 August 2017

Vincenzo Cerullo

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7 August 2017

Daniela Marzioni

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7 August 2017

Marco Colombatti

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7 August 2017

publication date

26 July 2011

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7 August 2017

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7 August 2017

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7 August 2017

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7 August 2017

page(s)

1858-1866

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Integrin targeted oncolytic adenoviruses Ad5-D24-RGD and Ad5-RGD-D24-GMCSF for treatment of patients with advanced chemotherapy refractory solid tumors

7 August 2017

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27 July 2018

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27 July 2018

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27 July 2018

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Anti-viral state segregates two molecular phenotypes of pancreatic adenocarcinoma: potential relevance for adenoviral gene therapy

27 July 2018

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27 July 2018

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27 July 2018

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In situ adenovirus vaccination engages T effector cells against cancer

27 July 2018

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27 July 2018

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An interferon-related gene signature for DNA damage resistance is a predictive marker for chemotherapy and radiation for breast cancer

27 July 2018

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A novel signaling pathway impact analysis.

27 July 2018

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Interferon-inducible antiviral effectors

27 July 2018

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Pre-processing of microarray data and analysis of differential expression

27 July 2018

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The current status of adenovirus-based cancer gene therapy

27 July 2018

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Redirecting adaptive immunity against foreign antigens to tumors for cancer therapy

27 July 2018

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Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.

27 July 2018

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Clinical trials with oncolytic adenovirus in China

27 July 2018

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Sensing infection by adenovirus: Toll-like receptor-independent viral DNA recognition signals activation of the interferon regulatory factor 3 master regulator

27 July 2018

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Nucleotide-binding oligomerization domain-like receptors: intracellular pattern recognition molecules for pathogen detection and host defense

27 July 2018

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In vivo establishment and characterization of a paclitaxel-resistant human ovarian cancer cell line showing enhanced growth properties and drug-resistance only in vivo

27 July 2018

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Transcriptional profiling of interferon regulatory factor 3 target genes: direct involvement in the regulation of interferon-stimulated genes

27 July 2018

1 reference

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Mineralocorticoid receptor affects AP-1 and nuclear factor-kappab activation in angiotensin II-induced cardiac injury

27 July 2018

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Inhibition of vesicular stomatitis virus mRNA synthesis by human MxA protein

27 July 2018

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Aldosterone-specific membrane receptors and rapid non-genomic actions of mineralocorticoids

27 July 2018

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Mouse Mx2 protein inhibits vesicular stomatitis virus but not influenza virus

27 July 2018

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Oncolytic adenovirus coding for granulocyte macrophage colony-stimulating factor induces antitumoral immunity in cancer patients

27 July 2018

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A high-throughput pharmacoviral approach identifies novel oncolytic virus sensitizers

26 September 2018

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Epithelial phenotype confers resistance of ovarian cancer cells to oncolytic adenoviruses

26 September 2018

1 reference

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Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

26 September 2018

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Innate immune response to adenoviral vectors is mediated by both Toll-like receptor-dependent and -independent pathways

26 September 2018

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AdvHSV-tk gene therapy with intravenous ganciclovir improves survival in human malignant glioma: a randomised, controlled study

26 September 2018

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China approves first gene therapy

26 September 2018

1 reference

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Enhanced therapeutic efficacy for ovarian cancer with a serotype 3 receptor-targeted oncolytic adenovirus

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188743

Summaries of Affymetrix GeneChip probe level data

26 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3188743

TNFalpha and IFNgamma induced by innate anti-adenoviral immune responses inhibit adenovirus-mediated transgene expression

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21792178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21792178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cancer gene therapy with targeted adenoviruses

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21792178

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2011.144

1 reference

7 August 2017

1 reference

7 August 2017

1 reference