Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress (Q35236033)

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28 February 2020

title

Hematopoiesis specific loss of Cdk2 and Cdk4 results in increased erythrocyte size and delayed platelet recovery following stress (English)

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28 February 2020

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1 reference

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28 February 2020

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28 February 2020

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28 February 2020

Chelsia Qiuxia Wang

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28 February 2020

Matias J Caldez

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28 February 2020

Shuhui Lim

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28 February 2020

Vinay Tergaonkar

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28 February 2020

Motomi Osato

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28 February 2020

publication date

23 January 2015

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28 February 2020

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28 February 2020

volume

100

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28 February 2020

issue

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28 February 2020

page(s)

431-438

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Cdks, cyclins and CKIs: roles beyond cell cycle regulation

28 February 2020

cites work

1 reference

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ATP-noncompetitive CDK inhibitors for cancer therapy: an overview

13 July 2018

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Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number

13 July 2018

1 reference

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Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.

13 July 2018

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From stem cell to red cell: regulation of erythropoiesis at multiple levels by multiple proteins, RNAs, and chromatin modifications

13 July 2018

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Down-regulation of Myc is essential for terminal erythroid maturation

13 July 2018

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Cell cycle, CDKs and cancer: a changing paradigm

13 July 2018

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A requirement for cyclin-dependent kinase 6 in thymocyte development and tumorigenesis

13 July 2018

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Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition.

13 July 2018

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Enucleation of cultured mouse fetal erythroblasts requires Rac GTPases and mDia2.

13 July 2018

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CDK inhibitors in cancer therapy: what is next?

13 July 2018

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Cdk1 is sufficient to drive the mammalian cell cycle

13 July 2018

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Cyclin D-Cdk4 is regulated by GATA-1 and required for megakaryocyte growth and polyploidization

13 July 2018

1 reference

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Cell size checkpoint control by the retinoblastoma tumor suppressor pathway

13 July 2018

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The Evi1 proto-oncoprotein blocks endomitosis in megakaryocytes by inhibiting sustained cyclin-dependent kinase 2 catalytic activity.

13 July 2018

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Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

13 July 2018

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Cdk2 knockout mice are viable

13 July 2018

1 reference

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Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

13 July 2018

1 reference

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

13 July 2018

1 reference

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Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum

13 July 2018

1 reference

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Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity

13 July 2018

1 reference

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Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

13 July 2018

1 reference

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Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts

13 July 2018

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The retinoblastoma protein and cell cycle control

13 July 2018

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Bromodeoxyuridine immunohistochemical determination of the lengths of the cell cycle and the DNA-synthetic phase for an anatomically defined population.

13 July 2018

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Loss of Cdk2 and Cdk4 induces a switch from proliferation to differentiation in neural stem cells.

13 July 2018

1 reference

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Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice

26 September 2018

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Role of Ras signaling in erythroid differentiation of mouse fetal liver cells: functional analysis by a flow cytometry-based novel culture system

26 September 2018

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VavCre transgenic mice: a tool for mutagenesis in hematopoietic and endothelial lineages.

26 September 2018

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Terminal differentiation of normal chicken erythroid progenitors: shortening of G1 correlates with loss of D-cyclin/cdk4 expression and altered cell size control

26 September 2018

1 reference

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Differential modulation of G1-S-phase cyclin-dependent kinase 2/cyclin complexes occurs during the acquisition of a polyploid DNA content

26 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25616574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25616574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25616574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3324/HAEMATOL.2014.106468

1 reference

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28 February 2020

1 reference

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28 February 2020

PubMed publication ID

25616574

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25616574%20AND%20SRC:MED&resulttype=core&format=json