Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia (Q35168360)

6 August 2017

title

Specific protein redirection as a transcriptional therapy approach for t(8;21) leukemia (English)

1 reference

6 August 2017

Carsten Müller-Tidow

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author name string

Björn Steffen

1 reference

6 August 2017

Hubert Serve

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6 August 2017

Wolfgang E Berdel

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6 August 2017

Shuchi Agrawal

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6 August 2017

Bryan Linggi

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6 August 2017

Thomas Büchner

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6 August 2017

Scott W Hiebert

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6 August 2017

language of work or name

English

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publication date

20 June 2003

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Proceedings of the National Academy of Sciences of the United States of America

6 August 2017

published in

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6 August 2017

volume

100

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6 August 2017

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6 August 2017

page(s)

8448-8453

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AML1-ETO downregulates the granulocytic differentiation factor C/EBPalpha in t(8;21) myeloid leukemia.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR-ABL tyrosine kinase.

28 July 2018

1 reference

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Interactions between adenovirus proteins and the p53 pathway: the development of ONYX-015.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Myb is required for self-renewal in a model system of early hematopoiesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Myb targeted therapeutics for the treatment of human malignancies

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Functional and physical interactions between AML1 proteins and an ETS protein, MEF: implications for the pathogenesis of t(8;21)-positive leukemias

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Myb and ets proteins are candidate regulators of c-kit expression in human hematopoietic cells.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Phosphorylation and activation of B-Myb by cyclin A-Cdk2.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

A dominant interfering Myb mutant causes apoptosis in T cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

An adenovirus mutant that replicates selectively in p53-deficient human tumor cells

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

C/EBP, c-Myb, and PU.1 cooperate to regulate the neutrophil elastase promoter

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

The AML1/ETO fusion protein blocks transactivation of the GM-CSF promoter by AML1B.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

The t(8;21) fusion protein interferes with AML-1B-dependent transcriptional activation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Functional domains of the t(8;21) fusion protein, AML-1/ETO.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

In vivo treatment of human leukemia in a scid mouse model with c-myb antisense oligodeoxynucleotides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

Core Binding Factor Cannot Synergistically Activate the Myeloperoxidase Proximal Enhancer in Immature Myeloid Cells without c-Myb

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=166249

c-myb transactivates the human cyclin A1 promoter and induces cyclin A1 gene expression

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12819347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Chromosomal patterns in myelocytic leukemia

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12819347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/12819347

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1330293100

1 reference

6 August 2017

0 references

1 reference

6 August 2017

1 reference