Mitochondrial membrane permeabilisation by Bax/Bak (Q35120714)

6 August 2017

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title

Mitochondrial membrane permeabilisation by Bax/Bak (English)

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6 August 2017

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https://api.crossref.org/works/10.1016/S0006-291X(03)00617-X

30 December 2023

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https://api.crossref.org/works/10.1016/S0006-291X(03)00617-X

30 December 2023

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https://api.crossref.org/works/10.1016/S0006-291X(03)00617-X

30 December 2023

Mauro Degli Esposti

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Caroline Dive

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language of work or name

English

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publication date

1 May 2003

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6 August 2017

9 May 2003

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National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12729579

full work available at URL

30 December 2023

https://api.elsevier.com/content/article/PII:S0006291X0300617X?httpAccept=text/xml

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DOI

https://api.crossref.org/works/10.1016/S0006-291X(03)00617-X

https://api.elsevier.com/content/article/PII:S0006291X0300617X?httpAccept=text/plain

30 December 2023

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DOI

https://api.crossref.org/works/10.1016/S0006-291X(03)00617-X

Biochemical and Biophysical Research Communications

30 December 2023

published in

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6 August 2017

volume

304

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6 August 2017

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6 August 2017

page(s)

455-461

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The Bcl2 family: regulators of the cellular life-or-death switch

6 August 2017

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Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

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Sequence and functional similarities between pro-apoptotic Bid and plant lipid transfer proteins

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Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis

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Cellular damage signals promote sequential changes at the N-terminus and BH-1 domain of the pro-apoptotic protein Bak.

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BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

7 January 2021

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A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis

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tBID Homooligomerizes in the mitochondrial membrane to induce apoptosis

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Bax is present as a high molecular weight oligomer/complex in the mitochondrial membrane of apoptotic cells

7 January 2021

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Bax, along with lipid conspirators, allows cytochrome c to escape mitochondria

7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

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Direct evidence for membrane pore formation by the apoptotic protein Bax

7 January 2021

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Bax and Bak coalesce into novel mitochondria-associated clusters during apoptosis

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Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis

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7 January 2021

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7 January 2021

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7 January 2021

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The expanding role of mitochondria in apoptosis

7 January 2021

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The pro-apoptotic protein, Bik, exhibits potent antitumor activity that is dependent on its BH3 domain

30 December 2023

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BH3 death domain peptide induces cell type-selective mitochondrial outer membrane permeability

30 December 2023

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Cell permeable Bcl-2 binding peptides: a chemical approach to apoptosis induction in tumor cells

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30 December 2023

Identifiers

DOI

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6 August 2017

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