Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury. (Q35124266)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

title

Deficiency of the planar cell polarity protein Vangl2 in podocytes affects glomerular morphogenesis and increases susceptibility to injury (English)

1 reference

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13 March 2020

1 reference

1 reference

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13 March 2020

Brittany L Rocque

1 reference

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13 March 2020

Sima Babayeva

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13 March 2020

Jane Li

1 reference

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13 March 2020

Lisa Nezvitsky

1 reference

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13 March 2020

Andrey V Cybulsky

1 reference

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13 March 2020

Philippe Gros

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13 March 2020

Elena Torban

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13 March 2020

publication date

21 August 2014

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145929%20AND%20SRC:MED&resulttype=core&format=json

Journal of the American Society of Nephrology

13 March 2020

published in

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13 March 2020

volume

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13 March 2020

issue

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13 March 2020

page(s)

576-586

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The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.

13 March 2020

cites work

1 reference

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Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2

13 July 2018

1 reference

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Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes

13 July 2018

1 reference

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Podocyte repopulation by renal progenitor cells following glucocorticoids treatment in experimental FSGS

13 July 2018

1 reference

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ARHGDIA: a novel gene implicated in nephrotic syndrome

13 July 2018

1 reference

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Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system

13 July 2018

1 reference

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Planar cell polarity and the developmental control of cell behavior in vertebrate embryos

13 July 2018

1 reference

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Role of the polarity protein Scribble for podocyte differentiation and maintenance

13 July 2018

1 reference

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Podocyte-specific loss of Cdc42 leads to congenital nephropathy

13 July 2018

1 reference

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Focal segmental glomerulosclerosis

13 July 2018

1 reference

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MYO1E mutations and childhood familial focal segmental glomerulosclerosis

13 July 2018

1 reference

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Human neural tube defects: Genetic causes and prevention

13 July 2018

1 reference

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Principles of planar polarity in animal development

13 July 2018

1 reference

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Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation

13 July 2018

1 reference

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Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes

13 July 2018

1 reference

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The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis

13 July 2018

1 reference

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Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis

13 July 2018

1 reference

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De novo expression of podocyte proteins in parietal epithelial cells during experimental glomerular disease

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Podocyte polarity signalling.

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Disruption of Myosin 1e promotes podocyte injury

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Inducible rodent models of acquired podocyte diseases.

13 July 2018

1 reference

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Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Development of the renal glomerulus: good neighbors and good fences

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Actin up: regulation of podocyte structure and function by components of the actin cytoskeleton

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation

13 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Asymmetric localization of Vangl2 and Fz3 indicate novel mechanisms for planar cell polarity in mammals

13 July 2018

1 reference

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The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

13 July 2018

1 reference

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Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family

13 July 2018

1 reference

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Branching morphogenesis and kidney disease

13 July 2018

1 reference

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CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility

13 July 2018

1 reference

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Gene targeting in kidney development

13 July 2018

1 reference

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The Wnt/planar cell polarity pathway component Vangl2 induces synapse formation through direct control of N-cadherin.

13 July 2018

1 reference

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The Frizzled-dependent planar polarity pathway locally promotes E-cadherin turnover via recruitment of RhoGEF2.

27 September 2018

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An expanding role of Vangl proteins in embryonic development

27 September 2018

1 reference

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Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome

27 September 2018

1 reference

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Hexagonal packing of Drosophila wing epithelial cells by the planar cell polarity pathway

27 September 2018

1 reference

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Complement C5b-9 membrane attack complex increases expression of endoplasmic reticulum stress proteins in glomerular epithelial cells

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Glomerular-specific gene excision in vivo.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4341486

Focal and segmental glomerulosclerosis in mice with podocyte-specific expression of mutant alpha-actinin-4

27 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25145929

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Experimental glomerulonephritis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25145929

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1681/ASN.2014040340

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145929%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

PubMed publication ID

25145929

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25145929%20AND%20SRC:MED&resulttype=core&format=json