Calcineurin A-alpha but not A-beta is required for normal kidney development and function (Q35103375)

6 August 2017

title

Calcineurin A-alpha but not A-beta is required for normal kidney development and function (English)

1 reference

6 August 2017

Jennifer L Gooch

1 reference

6 August 2017

Juan J Toro

series ordinal

1 reference

6 August 2017

Rebecca L Guler

series ordinal

1 reference

6 August 2017

Jeffrey L Barnes

series ordinal

1 reference

6 August 2017

language of work or name

English

0 references

publication date

1 November 2004

1 reference

The American Journal of Pathology

6 August 2017

published in

1 reference

6 August 2017

volume

165

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6 August 2017

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6 August 2017

page(s)

1755-1765

1 reference

Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery.

6 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice

9 July 2018

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Defective T cell development and function in calcineurin A beta -deficient mice

9 July 2018

1 reference

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Deregulated expression of the homeobox gene Cux-1 in transgenic mice results in downregulation of p27(kip1) expression during nephrogenesis, glomerular abnormalities, and multiorgan hyperplasia

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Calcineurin: form and function

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1.

9 July 2018

1 reference

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Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway

9 July 2018

1 reference

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A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

A calcineurin-dependent transcriptional pathway for cardiac hypertrophy

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes

9 July 2018

1 reference

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Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

T cell responses in calcineurin A alpha-deficient mice

9 July 2018

1 reference

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Tau domains, phosphorylation, and interactions with microtubules.

9 July 2018

1 reference

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Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron.

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Differential expression of calcineurin A isoforms in the diabetic kidney

9 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Cyclosporin A administration during pregnancy induces a permanent nephron deficit in young rabbits

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-gamma1 isoform

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurin-dependent mechanism

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Reduction of calcineurin activity in brain by antisense oligonucleotides leads to persistent phosphorylation of tau protein at Thr181 and Thr231.

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Cytoskeletal changes in the brains of mice lacking calcineurin A alpha

27 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1618665

Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes

27 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Calcineurin Aalpha plays an exclusive role in TCR signaling in mature but not in immature T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Measurement of Calcineurin Phosphatase Activity in Cell Extracts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Expression of the cyclin kinase inhibitor, p27kip1, in developing and mature human kidney

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2963430-X

Cyclosporin A stimulates transcription and procollagen secretion in tubulointerstitial fibroblasts and proximal tubular cells

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15509543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclosporin exerts a direct fibrogenic effect on human tubulointerstitial cells: roles of insulin-like growth factor I, transforming growth factor beta1, and platelet-derived growth factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15509543

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/S0002-9440(10)63430-X

1 reference

6 August 2017

1 reference

6 August 2017

1 reference