Lessons in obesity from transgenic animals (Q35037252)

5 August 2017

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title

Lessons in obesity from transgenic animals (English)

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5 August 2017

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Arch JR

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5 August 2017

publication date

1 November 2002

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Journal of Endocrinological Investigation

5 August 2017

published in

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

867-875

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Molecular characterization of the mouse agouti locus.

5 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FBF03344050

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Rodent obesity models: an overview

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

KO's and organisation of peptidergic feeding behavior mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Separate systems for serotonin and leptin in appetite control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

5-HT2C receptor modulation and the treatment of obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Role of brain insulin receptor in control of body weight and reproduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Increased energy expenditure, decreased adiposity, and tissue-specific insulin sensitivity in protein-tyrosine phosphatase 1B-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

FOXC2 is a winged helix gene that counteracts obesity, hypertriglyceridemia, and diet-induced insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

DGAT and triglyceride synthesis: a new target for obesity treatment?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

The metabolic consequences of altered glucose transporter expression in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Uncoupling proteins: functional characteristics and role in the pathogenesis of obesity and Type II diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Cholecystokinin: proofs and prospects for involvement in control of food intake and body weight

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

A new class of obesity genes encodes leukocyte adhesion receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

In vivo modulation of Hmgic reduces obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Mice lacking the M3 muscarinic acetylcholine receptor are hypophagic and lean.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Sim1 haploinsufficiency causes hyperphagia, obesity and reduction of the paraventricular nucleus of the hypothalamus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Orexins and feeding: special occasions or everyday occurrence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Anti-obesity drugs: a critical review of current therapies and future opportunities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Melanocortin-4 receptor mutations are a frequent and heterogeneous cause of morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Using mouse models to dissect the genetics of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Genetic variation in the beta 3-adrenergic receptor and an increased capacity to gain weight in patients with morbid obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Severe leptin resistance in brown fat-deficient uncoupling protein promoter-driven diphtheria toxin A mice despite suppression of hypothalamic neuropeptide Y and circulating corticosterone concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Leptin responsiveness in mice that ectopically express agouti protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Response of melanocortin-4 receptor-deficient mice to anorectic and orexigenic peptides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Independent and Additive Effects of Central POMC and Leptin Pathways on Murine Obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Response of neuropeptide Y-deficient mice to feeding effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Mice lacking melanin-concentrating hormone are hypophagic and lean

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Modest overexpression of neuropeptide Y in the brain leads to obesity after high-sucrose feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

The role of NPY in metabolic homeostasis: implications for obesity therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Cardiovascular response, feeding behavior and locomotor activity in mice lacking the NPY Y1 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Obesity and mild hyperinsulinemia found in neuropeptide Y-Y1 receptor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Role of the Y5 neuropeptide Y receptor in feeding and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

A review of rosiglitazone in type 2 diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

PPAR-gamma: adipogenic regulator and thiazolidinedione receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

A unique PPARgamma ligand with potent insulin-sensitizing yet weak adipogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Glycemic improvement in diabetic db/db mice by overexpression of the human insulin-regulatable glucose transporter (GLUT4).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Life without white fat: a transgenic mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Effects of pioglitazone on metabolic parameters, body fat distribution, and serum adiponectin levels in Japanese male patients with type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Triglycerides, fatty acids and insulin resistance--hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

How NOT to Approach the Obesity Problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Elevated metabolic rates in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

The Nutrition Society Medical Lecture. Obesity: from molecules to man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Abnormalities of energy expenditure and the development of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Obesity in Britain: gluttony or sloth?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Lessons from animal models of obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Glucocorticoids, 11beta-hydroxysteroid dehydrogenase, and fetal programming

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

A transgenic model of visceral obesity and the metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Mice lacking bombesin receptor subtype-3 develop metabolic defects and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Interleukin-6-deficient mice develop mature-onset obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Perilipin ablation results in a lean mouse with aberrant adipocyte lipolysis, enhanced leptin production, and resistance to diet-induced obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Suppression of body fat accumulation in myostatin-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Caveolin-1-deficient mice are lean, resistant to diet-induced obesity, and show hypertriglyceridemia with adipocyte abnormalities

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Relationship between impaired glucose tolerance, non-insulin-dependent diabetes mellitus and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FBF03344050

Improved glucose and lipid metabolism in genetically obese mice lacking aP2.

21 January 2018

1 reference

12 December 2020

Reduced body weight, adipose tissue, and leptin levels despite increased energy intake in female mice lacking acylation-stimulating protein

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12 December 2020

Adipose cell hyperplasia and enhanced glucose disposal in transgenic mice overexpressing GLUT4 selectively in adipose tissue

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12 December 2020

Leptin resistance in obese humans: does it exist and what does it mean?

1 reference

12 December 2020

Using gene knockout and transgenic techniques to study the physiology and pharmacology of beta3-adrenergic receptors

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12 December 2020

GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance.

1 reference

12 December 2020

Reciprocal relation of food intake and sympathetic activity: experimental observations and clinical implications

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12 December 2020

Interacting appetite-regulating pathways in the hypothalamic regulation of body weight

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12 December 2020

Food intake, body weight gain, and body composition of the young obese (ob/ob) mouse

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12 December 2020

Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass

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12 December 2020

Middle-aged C57BL/6 mice have impaired responses to leptin that are not improved by calorie restriction

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12 December 2020

Transgenic approach to the study of body weight regulation

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12 December 2020

Sibutramine: a novel anti-obesity drug. A review of the pharmacological evidence to differentiate it from d-amphetamine and d-fenfluramine

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12 December 2020

Identifiers

DOI

10.1007/BF03344050

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5 August 2017

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