Potassium channels as anti-epileptic drug targets (Q35035323)

5 August 2017

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title

Potassium channels as anti-epileptic drug targets (English)

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5 August 2017

Alan D Wickenden

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5 August 2017

publication date

1 December 2002

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

1055-1060

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Toward Understanding the Assembly and Structure of KATPChannels

5 August 2017

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7 January 2021

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Production of seizures and brain damage in rats by alpha-dendrotoxin, a selective K+ channel blocker

7 January 2021

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7 January 2021

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A potassium channel mutation in neonatal human epilepsy

7 January 2021

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Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain

7 January 2021

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Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neurone

7 January 2021

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Episodic ataxia/myokymia syndrome is associated with point mutations in the human potassium channel gene, KCNA1

7 January 2021

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Hyperalgesia in mice lacking the Kv1.1 potassium channel gene

7 January 2021

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M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain.

7 January 2021

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Myokymia and neonatal epilepsy caused by a mutation in the voltage sensor of the KCNQ2 K+ channel

7 January 2021

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Distribution of mRNA encoding the inwardly rectifying K+ channel, BIR1 in rat tissues

7 January 2021

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K+ channels openers prevent epilepsy induced by the bee venom peptide MCD

7 January 2021

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K+ channel openers decrease seizures in genetically epileptic rats

7 January 2021

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Neurotoicity of apamin and MCD peptide upon central application

7 January 2021

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Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice

7 January 2021

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Loss of the potassium channel beta-subunit gene, KCNAB2, is associated with epilepsy in patients with 1p36 deletion syndrome.

7 January 2021

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Mice transgenically overexpressing sulfonylurea receptor 1 in forebrain resist seizure induction and excitotoxic neuron death

7 January 2021

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Induction of seizures by the potent K+ channel-blocking scorpion venom peptide toxins tityustoxin-K(alpha) and pandinustoxin-K(alpha)

7 January 2021

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The effects of D-23129, a new experimental anticonvulsant drug, on neurotransmitter amino acids in the rat hippocampus in vitro

7 January 2021

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Effects of a cognition-enhancer, linopirdine (DuP 996), on M-type potassium currents (IK(M)) and some other voltage- and ligand-gated membrane currents in rat sympathetic neurons.

7 January 2021

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Heteromultimerization of G-protein-gated inwardly rectifying K+ channel proteins GIRK1 and GIRK2 and their altered expression in weaver brain

7 January 2021

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Modulation of KCNQ2/3 potassium channels by the novel anticonvulsant retigabine

7 January 2021

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Subunit composition determines Kv1 potassium channel surface expression

7 January 2021

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Potassium channel activators counteract anoxic hyperexcitability but not 4-aminopyridine-induced epileptiform activity in the rat hippocampal slice

7 January 2021

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Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2)

7 January 2021

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Experimental localization of Kv1 family voltage-gated K+ channel alpha and beta subunits in rat hippocampal formation.

7 January 2021

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Inactivation properties of voltage-gated K+ channels altered by presence of beta-subunit

7 January 2021

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Association and Colocalization of the Kvβ1 and Kvβ2 β-Subunits with Kv1 α-Subunits in Mammalian Brain K+Channel Complexes

7 January 2021

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D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.

7 January 2021

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The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunits

7 January 2021

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Charybdotoxin is a new member of the K+ channel toxin family that includes dendrotoxin I and mast cell degranulating peptide

7 January 2021

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Normal cerebellar development but susceptibility to seizures in mice lacking G protein-coupled, inwardly rectifying K+ channel GIRK2

7 January 2021

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A novel potassium channel gene, KCNQ2, is mutated in an inherited epilepsy of newborns

7 January 2021

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Deletion of the K(V)1.1 potassium channel causes epilepsy in mice

7 January 2021

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Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals, somata, and dendrites in the mouse brain

7 January 2021

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KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channel

7 January 2021

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Disruption of the epilepsy KCNQ2 gene results in neural hyperexcitability

7 January 2021

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Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4

7 January 2021

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Protective role of ATP-sensitive potassium channels in hypoxia-induced generalized seizure

7 January 2021

1 reference

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A novel mutation in the human voltage-gated potassium channel gene (Kv1.1) associates with episodic ataxia type 1 and sometimes with partial epilepsy

7 January 2021

2 references

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0028-3908%2802%2900237-X

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0028-3908(02)00237-X

1 reference

5 August 2017

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