Harnessing the p53-PUMA axis to overcome DNA damage resistance in renal cell carcinoma (Q35022460)

5 August 2017

title

Harnessing the p53-PUMA axis to overcome DNA damage resistance in renal cell carcinoma (English)

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5 August 2017

0 references

1 reference

Markus Hohenfellner

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5 August 2017

Sascha Pahernik

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5 August 2017

Yanis Tolstov

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5 August 2017

Wilfried Roth

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5 August 2017

Carsten Grüllich

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5 August 2017

Stefan Duensing

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5 August 2017

Aysenur Arslan

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5 August 2017

Xiaoguang Zhou

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5 August 2017

publication date

1 December 2014

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

1028-1035

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Combining histone deacetylase inhibitors with MDA-7/IL-24 enhances killing of renal carcinoma cells

5 August 2017

cites work

1 reference

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A novel HDAC inhibitor OBP-801 and a PI3K inhibitor LY294002 synergistically induce apoptosis via the suppression of survivin and XIAP in renal cell carcinoma

8 July 2018

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Comprehensive molecular characterization of clear cell renal cell carcinoma

8 July 2018

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A threshold mechanism mediates p53 cell fate decision between growth arrest and apoptosis

8 July 2018

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8 July 2018

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Selective killing of p53-deficient cancer cells by SP600125.

8 July 2018

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

8 July 2018

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Gene-specific repression of the p53 target gene PUMA via intragenic CTCF-Cohesin binding.

8 July 2018

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8 July 2018

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PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis

8 July 2018

1 reference

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PUMA, a potent killer with or without p53

8 July 2018

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Class I histone deacetylases 1, 2 and 3 are highly expressed in renal cell cancer.

8 July 2018

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Gene microarray analysis of human renal cell carcinoma: the effects of HDAC inhibition and retinoid treatment

8 July 2018

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Double inhibition of XIAP and Bcl-2 axis is beneficial for retrieving sensitivity of renal cell cancer to apoptosis

8 July 2018

1 reference

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Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.

8 July 2018

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Loss of the tissue-specific proapoptotic BH3-only protein Nbk/Bik is a unifying feature of renal cell carcinoma.

8 July 2018

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Adenovirus E1-transformed cells grow despite the continuous presence of transcriptionally active p53.

8 July 2018

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PUMA, a novel proapoptotic gene, is induced by p53

8 July 2018

1 reference

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PUMA induces the rapid apoptosis of colorectal cancer cells

8 July 2018

1 reference

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

8 July 2018

1 reference

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Frequent expression of Bcl-2 in renal-cell carcinomas carrying wild-type p53.

8 July 2018

1 reference

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The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage

8 July 2018

1 reference

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Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine

8 July 2018

1 reference

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The histone deacetylase inhibitor valproic acid alters growth properties of renal cell carcinoma in vitro and in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309250

Apoptosis and expression of Bcl-2, Bcl-XL, and Bax in renal cell carcinomas.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4309250

RENAL CELL CARCINOMA MIB-1, BAX AND BCL-2 EXPRESSION AND PROGNOSIS

25 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25499216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Biology and treatment of advanced renal cell carcinoma: a global perspective

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25499216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cyclin A/cdk2 activation is involved in hypoxia-induced apoptosis in cardiomyocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25499216

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.NEO.2014.09.012

1 reference

5 August 2017

1 reference

5 August 2017

1 reference