Emerging Therapies: Pleiotropic Multi-target Drugs to Treat Stroke Victims (Q35029799)

5 August 2017

title

Emerging Therapies: Pleiotropic Multi-target Drugs to Treat Stroke Victims (English)

1 reference

5 August 2017

1 reference

Paul A. Lapchak

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21666853

4 December 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=21666853

4 December 2024

publication date

1 June 2011

1 reference

full work available at URL

5 August 2017

https://link.springer.com/content/pdf/10.1007/s12975-011-0074-4.pdf

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21666853

https://europepmc.org/articles/PMC3109659

4 December 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21666853

https://europepmc.org/articles/PMC3109659?pdf=render

4 December 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21666853

https://doi.org/10.1007/s12975-011-0074-4

4 December 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21666853

http://link.springer.com/content/pdf/10.1007/s12975-011-0074-4.pdf

4 December 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1007/S12975-011-0074-4

http://link.springer.com/article/10.1007/s12975-011-0074-4/fulltext.html

4 December 2024

1 reference

https://api.crossref.org/works/10.1007/S12975-011-0074-4

http://link.springer.com/content/pdf/10.1007/s12975-011-0074-4

4 December 2024

1 reference

https://api.crossref.org/works/10.1007/S12975-011-0074-4

Translational stroke research

4 December 2024

published in

1 reference

5 August 2017

1 reference

5 August 2017

1 reference

5 August 2017

page(s)

129-135

1 reference

Sonothrombolysis: an emerging modality for the treatment of acute ischemic and hemorrhagic stroke

5 August 2017

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8 July 2018

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Reperfusion therapies for acute ischemic stroke: current pharmacological and mechanical approaches

8 July 2018

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New Approaches to Neuroprotective Drug Development

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Delayed treatment with a novel neurotrophic compound reduces behavioral deficits in rabbit ischemic stroke

8 July 2018

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Preclinical drug evaluation for combination therapy in acute stroke using systematic review, meta-analysis, and subsequent experimental testing

8 July 2018

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Comparison of the post-embolization effects of tissue-plasminogen activator and simvastatin on neurological outcome in a clinically relevant rat model of acute ischemic stroke

8 July 2018

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8 July 2018

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A new embolus injection method to evaluate intracerebral hemorrhage in New Zealand white rabbits

8 July 2018

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Trends in thrombolytic use for ischemic stroke in the United States

8 July 2018

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Translational stroke research using a rabbit embolic stroke model: a correlative analysis hypothesis for novel therapy development

8 July 2018

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A critical assessment of edaravone acute ischemic stroke efficacy trials: is edaravone an effective neuroprotective therapy?

8 July 2018

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Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials

8 July 2018

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Stroke location and brain function in an embolic rabbit stroke model

8 July 2018

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Building a tiered approach to in vitro predictive toxicity screening: a focus on assays with in vivo relevance

8 July 2018

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Heart Disease and Stroke Statistics--2010 Update: A Report From the American Heart Association

8 July 2018

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Mismatch-based delayed thrombolysis: a meta-analysis.

8 July 2018

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Severe blood-brain barrier disruption and surrounding tissue injury

8 July 2018

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Curcumin produces neuroprotective effects via activating brain-derived neurotrophic factor/TrkB-dependent MAPK and PI-3K cascades in rodent cortical neurons

8 July 2018

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Transcranial near infrared laser treatment (NILT) increases cortical adenosine-5'-triphosphate (ATP) content following embolic strokes in rabbits

8 July 2018

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Recombinant human erythropoietin in the treatment of acute ischemic stroke

8 July 2018

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Efficacy and safety of tissue plasminogen activator 3 to 4.5 hours after acute ischemic stroke: a metaanalysis.

8 July 2018

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Effects of NXY-059 in experimental stroke: an individual animal meta-analysis

8 July 2018

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Re-canalization in acute ischemic stroke: the strategies

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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A novel approach to screening for new neuroprotective compounds for the treatment of stroke

8 July 2018

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Neuroprotective effects of curcumin

8 July 2018

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A critical appraisal of the NXY-059 neuroprotection studies for acute stroke: a need for more rigorous testing of neuroprotective agents in animal models of stroke

8 July 2018

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Advances in ischemic stroke treatment: neuroprotective and combination therapies

8 July 2018

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Neurovascular proteases in brain injury, hemorrhage and remodeling after stroke

8 July 2018

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Brain protection by anesthetic agents

8 July 2018

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8 July 2018

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NXY-059 for acute ischemic stroke

8 July 2018

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Neuroprotective effects of anesthetic agents

8 July 2018

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Stroke--incidence, mortality, morbidity and risk.

8 July 2018

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The ischemic penumbra: identification, evolution and treatment concepts

8 July 2018

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Development of thrombolytic therapy for stroke: a perspective

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Recommendations for clinical trial evaluation of acute stroke therapies.

8 July 2018

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Diagnostic and therapeutic applications of azulenyl nitrone spin traps

8 July 2018

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Timing of recanalization after tissue plasminogen activator therapy determined by transcranial doppler correlates with clinical recovery from ischemic stroke

8 July 2018

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Excitatory synaptic transmission mediated by NMDA receptors is more sensitive to isoflurane than are non-NMDA receptor-mediated responses

8 July 2018

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Antioxidants, oxidative stress, and degenerative neurological disorders

8 July 2018

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Stroke treatment economic model (STEM): predicting long-term costs from functional status.

8 July 2018

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Newer thrombolytic agents

8 July 2018

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Underlying structure of the National Institutes of Health Stroke Scale: results of a factor analysis. NINDS tPA Stroke Trial Investigators

8 July 2018

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Ischemic cell death in brain neurons

8 July 2018

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Pathobiology of ischaemic stroke: an integrated view

8 July 2018

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Pathophysiology of the ischemic penumbra--revision of a concept

8 July 2018

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8 July 2018

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Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

8 July 2018

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Tissue plasminogen activator for acute ischemic stroke

8 July 2018

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Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (1).

8 July 2018

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The pathophysiology of stroke: a review with molecular considerations.

8 July 2018

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Thrombolytic therapy. A new strategy for the treatment of acute myocardial infarction (2).

8 July 2018

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Ischemic stroke subtypes: a population-based study of incidence and risk factors

8 July 2018

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Reperfusion and outcomes in Penumbra vs. systemic tissue plasminogen activator clinical trials.

21 January 2018

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Acute stroke care in the US: results from 4 pilot prototypes of the Paul Coverdell National Acute Stroke Registry

21 January 2018

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Effect of a novel free radical scavenger, edaravone (MCI-186), on acute brain infarction. Randomized, placebo-controlled, double-blind study at multicenters

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21 January 2018

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21 January 2018

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Stilbazulenyl nitrone (STAZN): a nitronyl-substituted hydrocarbon with the potency of classical phenolic chain-breaking antioxidants

21 January 2018

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Stilbazulenyl nitrone, a novel azulenyl nitrone antioxidant: improved neurological deficit and reduced contusion size after traumatic brain injury in rats

21 January 2018

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Stilbazulenyl nitrone, a novel antioxidant, is highly neuroprotective in focal ischemia

21 January 2018

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Baicalein, an antioxidant 12/15-lipoxygenase inhibitor improves clinical rating scores following multiple infarct embolic strokes

21 January 2018

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Efficacy of IV tissue plasminogen activator in acute stroke: does stroke subtype really matter?

21 January 2018

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The lipophilic multifunctional antioxidant edaravone (radicut) improves behavior following embolic strokes in rabbits: a combination therapy study with tissue plasminogen activator

21 January 2018

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Continuous monitoring of changes in plasma nitrite following cerebral ischemia in a rabbit embolic stroke model

21 January 2018

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Executive Summary: Heart Disease and Stroke Statistics—2010 Update

25 October 2018

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Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic Stroke

21 January 2018

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The thrombolytic therapy of acute myocardial infarction

21 January 2018

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12 December 2020

On the thrombolytic therapy of recent myocardial infarction. 2. Results of electrocardiographic studies

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12 December 2020

Thrombolytic therapy of recent myocardial infarction. I. Introduction, plan of trial, general clinical results

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12 December 2020

Dipyridamole Treatment Prior to Stroke Onset: Examining Post-stroke Cerebral Circulation and Outcome in Rabbits

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12 December 2020

Routine use of intravenous low-dose recombinant tissue plasminogen activator in Japanese patients: general outcomes and prognostic factors from the SAMURAI register

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12 December 2020

NXY-059 for the treatment of acute ischemic stroke

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12 December 2020

Heterogeneity of stroke pathophysiology and neuroprotective clinical trial design

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12 December 2020

[On thrombolytic therapy of a recent myocardial infarct. I. Introduction, treatment plans, general clinical results]

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12 December 2020

Ischemic stroke subtypes : a population-based study of functional outcome, survival, and recurrence

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12 December 2020

German medical monthly

308

R Schmutzler

1966

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4 December 2024

M Sinha

2009

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4 December 2024

Identifiers

1 reference

5 August 2017

1 reference

5 August 2017

1 reference