RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients (Q35010521)

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English	RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

5 August 2017

RKIP phosphorylation and STAT3 activation is inhibited by oxaliplatin and camptothecin and are associated with poor prognosis in stage II colon cancer patients (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

phosphorylation

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based on heuristic

inferred from title

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Peter J Quesenberry

7

object named as

Peter J Quesenberry

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Europe PubMed Central

PubMed publication ID

5 August 2017

author name string

Sam Cross-Knorr

1

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5 August 2017

Shaolei Lu

2

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Europe PubMed Central

PubMed publication ID

5 August 2017

Kimberly Perez

3

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Europe PubMed Central

PubMed publication ID

5 August 2017

Sara Guevara

4

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Kate Brilliant

5

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Claudio Pisano

6

1 reference

Europe PubMed Central

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5 August 2017

Murray B Resnick

8

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5 August 2017

Devasis Chatterjee

9

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5 August 2017

language of work or name

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publication date

8 October 2013

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Europe PubMed Central

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5 August 2017

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Europe PubMed Central

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5 August 2017

13

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Europe PubMed Central

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5 August 2017

463

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Europe PubMed Central

PubMed publication ID

5 August 2017

Geographic analysis of RKIP expression and its clinical relevance in colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

RKIP: much more than Raf kinase inhibitory protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Regulation of RKIP function by Helicobacter pylori in gastric cancer

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8 July 2018

A new model for raf kinase inhibitory protein induced chemotherapeutic resistance

1 reference

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8 July 2018

IL-6/IL-6 receptor system and its role in physiological and pathological conditions

1 reference

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8 July 2018

STAT3 is necessary for proliferation and survival in colon cancer-initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

The DNA damage mark pH2AX differentiates the cytotoxic effects of small molecule HDAC inhibitors in ovarian cancer cells

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8 July 2018

Dynamics of the STAT3 transcription factor: nuclear import dependent on Ran and importin-β1.

1 reference

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8 July 2018

Global cancer statistics

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8 July 2018

Immunogenic death of colon cancer cells treated with oxaliplatin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Improved overall survival with oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment in stage II or III colon cancer in the MOSAIC trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells

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Targeting the cytoplasmic and nuclear functions of signal transducers and activators of transcription 3 for cancer therapy

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8 July 2018

The resurgence of platinum-based cancer chemotherapy

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Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan

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Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer

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8 July 2018

Interleukin-6: from basic science to medicine--40 years in immunology

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8 July 2018

Expression of activated signal transducer and activator of transcription 3 predicts expression of vascular endothelial growth factor in and angiogenic phenotype of human gastric cancer

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8 July 2018

Implication of STAT3 signaling in human colonic cancer cells during intestinal trefoil factor 3 (TFF3) -- and vascular endothelial growth factor-mediated cellular invasion and tumor growth.

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8 July 2018

Stat3 dimerization regulated by reversible acetylation of a single lysine residue

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

TGF-beta suppresses tumor progression in colon cancer by inhibition of IL-6 trans-signaling.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Recent phase III trials of fluorouracil, irinotecan, and oxaliplatin as chemotherapy for metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

RKIP sensitizes prostate and breast cancer cells to drug-induced apoptosis

1 reference

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8 July 2018

Requirement of p53 targets in chemosensitization of colonic carcinoma to death ligand therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

8 July 2018

Identification of 5-fluorouracil-inducible target genes using cDNA microarray profiling.

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8 July 2018

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein

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8 July 2018

Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

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8 July 2018

The crystal structure of PEBP-2, a homologue of the PEBP/RKIP family

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8 July 2018

Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention

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8 July 2018

Paracrine repercussions of preconditioning on angiogenesis and apoptosis of endothelial cells

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8 July 2018

Raf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activation

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8 July 2018

Negative regulation of Janus kinases

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Constitutive activation of JAK-STAT3 signaling by BRCA1 in human prostate cancer cells

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8 July 2018

Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856511

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Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial

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Binding of Gbetagamma subunits to cRaf1 downregulates G-protein-coupled receptor signalling

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Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP

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8 July 2018

Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway

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Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway

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Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

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Molecular cloning and expression of an IL-6 signal transducer, gp130

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Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice.

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Constitutive activation of Stat3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells

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Randomized phase III trial comparing biweekly infusional fluorouracil/leucovorin alone or with irinotecan in the adjuvant treatment of stage III colon cancer: PETACC-3.

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Raf kinase inhibitor protein expression combined with peritoneal involvement and lymphovascular invasion predicts prognosis in Dukes' B colorectal cancer patients

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Systematic analysis of proteins from different signaling pathways in the tumor center and the invasive front of colorectal cancer.

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Raf kinase inhibitor protein expression in a survival analysis of colorectal cancer patients.

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26 October 2018

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

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12 December 2020

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Enhanced expression of interleukin-6 in bone and serum of metastatic renal cell carcinoma

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12 December 2020

based on heuristic

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Colorectal cancer

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https://pubmed.ncbi.nlm.nih.gov/24098947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 signaling promotes tumor growth in colorectal cancer

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https://pubmed.ncbi.nlm.nih.gov/24098947

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 level in patients with colorectal cancer

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https://pubmed.ncbi.nlm.nih.gov/24098947

12 December 2020

based on heuristic

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Loss of Raf-1 Kinase Inhibitor Protein Expression Is Associated With Tumor Progression and Metastasis in Colorectal Cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/24098947

12 December 2020

based on heuristic

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Inverse association between Raf Kinase Inhibitory Protein and signal transducers and activators of transcription 3 expression in gastric adenocarcinoma patients: implications for clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/24098947

12 December 2020

based on heuristic

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Identifiers

10.1186/1471-2407-13-463

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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