Inhibition of cysteine proteases in acute and chronic spinal cord injury (Q35006494)

5 August 2017

1 reference

title

Inhibition of cysteine proteases in acute and chronic spinal cord injury (English)

1 reference

5 August 2017

Swapan K Ray

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5 August 2017

Supriti Samantaray

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5 August 2017

Joshua A Smith

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5 August 2017

Denise D Matzelle

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5 August 2017

Arabinda Das

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5 August 2017

Naren L Banik

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5 August 2017

publication date

1 April 2011

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5 August 2017

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5 August 2017

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5 August 2017

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5 August 2017

page(s)

180-186

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Estrogen receptor agonists and estrogen attenuate TNF- -induced apoptosis in VSC4.1 motoneurons

5 August 2017

cites work

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Neuroprotective efficacy of estrogen in experimental spinal cord injury in rats

8 July 2018

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Physiological low dose of estrogen-protected neurons in experimental spinal cord injury

8 July 2018

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Postinjury estrogen treatment of chronic spinal cord injury improves locomotor function in rats

8 July 2018

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The inhibition of apoptosis by melatonin in VSC4.1 motoneurons exposed to oxidative stress, glutamate excitotoxicity, or TNF-alpha toxicity involves membrane melatonin receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Effect of endogenous androgens on 17beta-estradiol-mediated protection after spinal cord injury in male rats

8 July 2018

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Therapeutic potential of melatonin in traumatic central nervous system injury

8 July 2018

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Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Immunohistochemical study of cathepsin D in the spinal cords of rats with clip compression injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Cathepsins: key modulators of cell death and inflammatory responses

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

8 July 2018

Lysosomes in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Intraspinal MDL28170 microinjection improves functional and pathological outcome following spinal cord injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Melatonin attenuates calpain upregulation, axonal damage and neuronal death in spinal cord injury in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Caspase-3 activity is reduced after spinal cord injury in mice lacking dynorphin: differential effects on glia and neurons.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Mesenchymal stem cells from rat bone marrow downregulate caspase-3-mediated apoptotic pathway after spinal cord injury in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Lysosomal cysteine cathepsins: signaling pathways in apoptosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Protease signalling in cell death: caspases versus cysteine cathepsins.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Inhibitors of cathepsin B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Overview of cell death signaling pathways

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Estrogen as a multi-active neuroprotective agent in traumatic injuries

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Effects of gender on neurologic and functional recovery after spinal cord injury.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Systemic administration of 17beta-estradiol reduces apoptotic cell death and improves functional recovery following traumatic spinal cord injury in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Calpain and its involvement in the pathophysiology of CNS injuries and diseases: therapeutic potential of calpain inhibitors for prevention of neurodegeneration

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Epidemiology, demographics, and pathophysiology of acute spinal cord injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Microglial secreted cathepsin B induces neuronal apoptosis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Review of current evidence for apoptosis after spinal cord injury.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Caspase pathways, neuronal apoptosis, and CNS injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Methylprednisolone for acute spinal cord injury: an inappropriate standard of care

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

E-64-d prevents both calpain upregulation and apoptosis in the lesion and penumbra following spinal cord injury in rats

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Caspase and calpain substrates: roles in synaptic plasticity and cell death

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Apoptosis after traumatic human spinal cord injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Human Estrogen Receptor β Binds DNA in a Manner Similar to and Dimerizes with Estrogen Receptor α

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Emerging roles for cysteine proteases in human biology

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Pathophysiology of spinal cord trauma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Calcium-activated neutral protease and its endogenous inhibitor. Activation at the cell membrane and biological function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Proteolytic enzymes in experimental spinal cord injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Inhibition of calpain-mediated apoptosis by E-64 d-reduced immediate early gene (IEG) expression and reactive astrogliosis in the lesion and penumbra following spinal cord injury in rats

8 July 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

The neuroprotective effects of z-DEVD.fmk, a caspase-3 inhibitor, on traumatic spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Cytoskeletal disruption following contusion injury to the rat spinal cord.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Role of Calpain in Spinal Cord Injury: Effects of Calpain and Free Radical Inhibitorsa

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Sustained calpain inhibition improves locomotor function and tissue sparing following contusive spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Increased calpain expression is associated with apoptosis in rat spinal cord injury: calpain inhibitor provides neuroprotection

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Calpastatin is up-regulated in response to hypoxia and is a suicide substrate to calpain after neonatal cerebral hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Calpain inhibitor prevented apoptosis and maintained transcription of proteolipid protein and myelin basic protein genes in rat spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Calpain inhibitors prevent neuronal cell death and ameliorate motor disturbances after compression-induced spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Acute rolipram/thalidomide treatment improves tissue sparing and locomotion after experimental spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Involvement of mitochondrial signaling pathways in the mechanism of Fas-mediated apoptosis after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Apoptotic and anti-apoptotic mechanisms following spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

FAS deficiency reduces apoptosis, spares axons and improves function after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

FK506 treatment inhibits caspase-3 activation and promotes oligodendroglial survival following traumatic spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Minocycline neuroprotects, reduces microgliosis, and inhibits caspase protease expression early after spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Inhibition of proteolysis by a cyclooxygenase inhibitor, indomethacin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Cathepsin B mRNA and protein expression following contusion spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Cathepsin B-dependent motor neuron death after nerve injury in the adult mouse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

17beta-estradiol is protective in spinal cord injury in post- and pre-menopausal rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Estrogen attenuated markers of inflammation and decreased lesion volume in acute spinal cord injury in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Estrogen treatment of spinal cord injury attenuates calpain activation and apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Effect of 17beta-estradiol on functional outcome, release of cytokines, astrocyte reactivity and inflammatory spreading after spinal cord injury in male rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Estrogen-induced Bcl-2 expression after spinal cord injury is mediated through phosphoinositide-3-kinase/Akt-dependent CREB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Maternal and developmental toxicity evaluation of melatonin administered orally to pregnant Sprague-Dawley rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Attenuation in the evolution of experimental spinal cord trauma by treatment with melatonin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Melatonin reduces stress-activated/mitogen-activated protein kinases in spinal cord injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Synergistic effect of melatonin on exercise-induced neuronal reconstruction and functional recovery in a spinal cord injury animal model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Melatonin-induced neuroprotection after closed head injury is associated with increased brain antioxidants and attenuated late-phase activation of NF-kappaB and AP-1.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Cell death in spinal cord injury (SCI) requires de novo protein synthesis. Calpain inhibitor E-64-d provides neuroprotection in SCI lesion and penumbra

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Calpain activity and expression increased in activated glial and inflammatory cells in penumbra of spinal cord injury lesion.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3101838

Pretreatment with Calpain Inhibitor CEP-4143 Inhibits Calpain I Activation and Cytoskeletal Degradation, Improves Neurological Function, and Enhances Axonal Survival After Traumatic Spinal Cord Injury

26 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS13311-011-0037-1

Subclinical atherosclerosis is related to injury level but not to inflammatory parameters in spinal cord injury subjects

21 January 2018

1 reference

12 December 2020

Comparison of the effects of melatonin and methylprednisolone in experimental spinal cord injury

1 reference

12 December 2020

Calpain in the pathophysiology of spinal cord injury: neuroprotection with calpain inhibitors

1 reference

12 December 2020

Early induction of secondary injury factors causing activation of calpain and mitochondria-mediated neuronal apoptosis following spinal cord injury in rats

1 reference

12 December 2020

The Effects of Spinal Cord Trauma on Myelin

1 reference

12 December 2020

Degradation of cytoskeletal proteins in experimental spinal cord injury

1 reference

12 December 2020

Proteolysis of the calcium-dependent protease inhibitor by myocardial calcium-dependent protease

1 reference

12 December 2020

Rapid Calpain I Activation and Cytoskeletal Protein Degradation Following Traumatic Spinal Cord Injury: Attenuation with Riluzole Pretreatment

1 reference

12 December 2020

Role of calpain in spinal cord injury: effects of calpain and free radical inhibitors

1 reference

12 December 2020

Selective caspase activation may contribute to neurological dysfunction after experimental spinal cord trauma

1 reference

12 December 2020

A mapping study of caspase-3 activation following acute spinal cord contusion in rats

1 reference

12 December 2020

Recombinant human erythropoietin decreases myeloperoxidase and caspase-3 activity and improves early functional results after spinal cord injury in rats

1 reference

12 December 2020

Direct evidence for calpain involvement in apoptotic death of neurons in spinal cord injury in rats and neuroprotection with calpain inhibitor

1 reference

12 December 2020

Effect of 17beta-estradiol on signal transduction pathways and secondary damage in experimental spinal cord trauma

1 reference

12 December 2020

10.1007/S13311-011-0037-1

Identifiers

DOI

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5 August 2017

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5 August 2017

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