Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer (Q34917506)

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scientific article published on March 17, 2011

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English	Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer	scientific article published on March 17, 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ribavirin treatment effects on breast cancers overexpressing eIF4E, a biomarker with prognostic specificity for luminal B-type breast cancer (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ribavirin Treatment Effects on Breast Cancers Overexpressing eIF4E, a Biomarker with Prognostic Specificity for Luminal B-Type Breast Cancer (English)

1 reference

10.1158/1078-0432.CCR-10-2334

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2334

27 November 2024

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Christina Yau

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5 August 2017

Katherine L B Borden

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Katherine L. B. Borden

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21415224

27 November 2024

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Filippa Pettersson

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Biljana Culjkovic-Kraljacic

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5 August 2017

Hélène Retrouvey

5

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5 August 2017

Rachel Puckett

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5 August 2017

Caroline Rousseau

9

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5 August 2017

Eftihia Cocolakis

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5 August 2017

Monica C. Dobocan

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27 November 2024

Ludmila M. Flores

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27 November 2024

Ian E. Krop

8

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27 November 2024

Christopher C. Benz

12

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27 November 2024

Wilson H. Miller

13

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27 November 2024

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publication date

17 March 2011

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5 August 2017

full work available at URL

http://clincancerres.aacrjournals.org/content/17/9/2874.full.pdf

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27 November 2024

https://europepmc.org/articles/PMC3086959

online access status

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21415224

27 November 2024

https://europepmc.org/articles/PMC3086959?pdf=render

Portable Document Format

online access status

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Europe PubMed Central

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21415224

27 November 2024

https://doi.org/10.1158/1078-0432.ccr-10-2334

online access status

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A21415224

27 November 2024

https://aacrjournals.org/clincancerres/article-pdf/17/9/2874/2004104/2874.pdf

Portable Document Format

1 reference

10.1158/1078-0432.CCR-10-2334

https://api.crossref.org/works/10.1158/1078-0432.CCR-10-2334

27 November 2024

Clinical Cancer Research

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

17

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Europe PubMed Central

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5 August 2017

9

1 reference

Europe PubMed Central

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5 August 2017

2874-2884

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

Ribavirin as an anti-cancer therapy: acute myeloid leukemia and beyond?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E

1 reference

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PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality

1 reference

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The applicability of mTOR inhibition in solid tumors.

1 reference

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Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer

1 reference

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8 July 2018

Combined analysis of eIF4E and 4E-binding protein expression predicts breast cancer survival and estimates eIF4E activity

1 reference

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8 July 2018

Supervised risk predictor of breast cancer based on intrinsic subtypes

1 reference

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Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.

1 reference

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Frequent PTEN genomic alterations and activated phosphatidylinositol 3-kinase pathway in basal-like breast cancer cells

1 reference

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8 July 2018

Ribavirin targets eIF4E dependent Akt survival signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling

1 reference

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8 July 2018

eIF4E, the mRNA cap-binding protein: from basic discovery to translational research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

The eIF4E RNA regulon promotes the Akt signaling pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Tumor-specific RNAi targeting eIF4E suppresses tumor growth, induces apoptosis and enhances cisplatin cytotoxicity in human breast carcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Targeting the eukaryotic translation initiation factor 4E for cancer therapy

1 reference

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8 July 2018

Therapeutic suppression of translation initiation factor eIF4E expression reduces tumor growth without toxicity

1 reference

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8 July 2018

Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Controlling gene expression through RNA regulons: the role of the eukaryotic translation initiation factor eIF4E.

1 reference

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8 July 2018

A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

1 reference

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8 July 2018

eIF4E is a central node of an RNA regulon that governs cellular proliferation

1 reference

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8 July 2018

Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study

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8 July 2018

The molecular portraits of breast tumors are conserved across microarray platforms

1 reference

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8 July 2018

mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

1 reference

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8 July 2018

Homeodomain proteins and eukaryotic translation initiation factor 4E (eIF4E): an unexpected relationship

1 reference

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Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition.

1 reference

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8 July 2018

Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

eIF4E promotes nuclear export of cyclin D1 mRNAs via an element in the 3'UTR

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Regulation of cap-dependent translation by eIF4E inhibitory proteins

1 reference

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8 July 2018

Eukaryotic translation initiation factor 4E activity is modulated by HOXA9 at multiple levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3086959

8 July 2018

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

1 reference

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8 July 2018

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8 July 2018

Activation of translation complex eIF4F is essential for the genesis and maintenance of the malignant phenotype in human mammary epithelial cells

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8 July 2018

The emerging roles of translation factor eIF4E in the nucleus

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PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

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Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin.

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Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer

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Detection of eIF4E gene amplification in breast cancer by competitive PCR.

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The proto-oncogene/translation factor eIF4E: A survey of its expression in breast carcinomas

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High eIF4E, VEGF, and microvessel density in stage I to III breast cancer

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https://pubmed.ncbi.nlm.nih.gov/21415224

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inferred from PubMed ID database lookup

A prospective trial on initiation factor 4E (eIF4E) overexpression and cancer recurrence in node-negative breast cancer

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/1078-0432.CCR-10-2334

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 August 2017

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