Signaling networks in the pathophysiology and treatment of mood disorders (Q34778245)

4 August 2017

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title

Signaling networks in the pathophysiology and treatment of mood disorders (English)

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4 August 2017

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Todd D Gould

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4 August 2017

Husseini K Manji

series ordinal

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4 August 2017

publication date

1 August 2002

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Journal of Psychosomatic Research

4 August 2017

published in

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4 August 2017

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4 August 2017

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4 August 2017

page(s)

687-697

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Molecular and cellular mechanisms of cardiac arrhythmias

4 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Basic concepts in the study of diseases with complex genetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Signal transduction pathways. Molecular targets for lithium's actions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Anti-bipolar therapy: mechanism of action of lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Enhanced protein kinase C activity and translocation in bipolar affective disorder brains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Hyperfunctional G proteins in mononuclear leukocytes of patients with mania.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Mononuclear leukocyte levels of G proteins in depressed patients with bipolar disorder or major depressive disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Abnormal G protein alpha(s) - and alpha(i2)-subunit mRNA expression in bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Guanine nucleotide binding proteins in opioid-dependent patients

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Reduced G protein functions and immunoreactive levels in mononuclear leukocytes of patients with depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Density of guanine nucleotide-binding proteins in platelets of patients with major depression: increased abundance of the G alpha i2 subunit and down-regulation by antidepressant drug treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Regulation of signal transduction pathways and gene expression by mood stabilizers and antidepressants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Signal-transducing G proteins and antidepressant drugs: evidence for modulation of alpha subunit gene expression in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Beta-adrenoceptor and post-receptor components show different rates of desensitization to desipramine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Direct influence of antidepressants on GTP binding protein of adenylate cyclase in cell membranes of the cerebral cortex of rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Guanosine triphosphate activation of brain adenylate cyclase: enhancement by long-term antidepressant treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Post-receptor-mediated increases in adenylate cyclase activity after chronic antidepressant treatment: relationship to receptor desensitization.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effects of subchronic administration of antidepressants and anxiolytics on levels of the alpha subunits of G proteins in the rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lack of effect of chronic antidepressant treatment on Gs and Gi alpha-subunit protein and mRNA levels in the rat cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Alpha-1 adrenergic receptor binding and adrenergic-stimulated cyclic AMP production in rat cerebral cortex after chronic lithium treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic lithium regulates the expression of adenylate cyclase and Gi-protein alpha subunit in rat cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Selective effects of long-term lithium and carbamazepine administration on G-protein subunit expression in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effects of chronic lithium and carbamazepine treatment on G-protein subunit expression in rat cerebral cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

In Vivo Evidence that Lithium Inactivates Gi Modulation of Adenylate Cyclase in Brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The cyclic AMP second messenger system in man: the effects of heredity, hormones, drugs, aluminum, age and disease on signal amplification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Platelet adenylate cyclase activity in depression and after clomipramine and lithium treatment: relation to serotonergic function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The mechanisms of action of lithium. II. Effects on adenylate cyclase activity and beta-adrenergic receptor binding in normal subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effect of lithium in vitro and after chronic treatment on human platelet adenylate cyclase activity: Postreceptor modification of second messenger signal amplification

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium administration modulates platelet Gi in humans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effect of in vivo lithium treatment on (-)isoproterenol-stimulated cAMP accumulation in lymphocytes of healthy subjects and patients with affective psychoses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effect of lithium on prostaglandin F1-stimulated adenylate cyclase activity of human platelets

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Biochemical and functional evidence of supersensitive platelet alpha 2-adrenoceptors in major affective disorder. Effect of long-term lithium carbonate treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Guanine nucleotide-binding proteins in bipolar affective disorder. Effects of long-term lithium treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium, but not carbamazepine, potentiates hyperactivity induced by intra-accumbens cholera toxin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effects of valproic acid on beta-adrenergic receptors, G-proteins, and adenylyl cyclase in rat C6 glioma cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

No abnormality in the gene for the G protein stimulatory alpha subunit in patients with bipolar disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Cyclic AMP signaling and gene regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Is CREB a key to neuronal survival?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Reduced sensitivity of lymphocyte beta-adrenergic receptors in patients with endogenous depression and psychomotor agitation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Cyclic AMP second-messenger signal amplification in depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Blunted beta-adrenergic responsivity of peripheral blood mononuclear cells in endogenous depression. Isoproterenol dose-response studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effects of lithium on second messenger systems in the brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Changes in lymphocyte beta-adrenergic receptors in depression and mania

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Reduced [3H]cyclic AMP binding in postmortem brain from subjects with bipolar affective disorder.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Differential inhibitory noradrenergic responses to clonidine in 25 depressed patients and 25 normal control subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Platelet alpha 2-adrenergic receptors in depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Adrenergic receptor sensitivity in depression. Effects of clonidine in depressed patients and healthy subjects.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Beta-adrenergic receptor function in affective illness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Beta-adrenoceptor binding defects in cell lines from families with manic-depressive disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic antidepressant administration alters the subcellular distribution of cyclic AMP-dependent protein kinase in rat frontal cortex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Second messenger-regulated protein kinases in the brain: their functional role and the action of antidepressant drugs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

A Molecular and Cellular Theory of Depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Increased temporal cortex CREB concentrations and antidepressant treatment in major depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Post-receptor signaling pathways in the pathophysiology and treatment of mood disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium regulates PKC-mediated intracellular cross-talk and gene expression in the CNS in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium effects on noradrenergic-linked adenylate cyclase activity in intact rat brain: an in vivo microdialysis study

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

A bimodal model of the mechanism of action of lithium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium inhibition of forskolin-stimulated adenylate cyclase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Mode of action of lithium on the catalytic unit of adenylate cyclase from rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The effects of lithium in vitro and ex vivo on adenylate cyclase in brain are exerted by distinct mechanisms

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Effects of lithium in vitro and ex vivo on components of the adenylate cyclase system in membranes from the cerebral cortex of the rat

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Anticonvulsant Drug Actions on In Vitro and In Vivo Levels of Cyclic AMP in the Mouse Brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Interactions of antiepileptic drugs on adenylate cyclase and phosphodiesterases in rat and mouse cerebrum

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Carbamazepine distinguishes between adenosine receptors that mediate different second messenger responses

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic carbamazepine down-regulates adenosine A2 receptors: studies with the putative selective adenosine antagonists PD115,199 and PD116,948

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Attenuation of cyclic AMP production by carbamazepine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Inositol phosphate biochemistry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Signal transduction by protein kinase C in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The MARCKS brothers: a family of protein kinase C substrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

CaM-kinases: modulators of synaptic plasticity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The control of neuronal Ca2+ homeostasis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Reduced frontal cortex inositol levels in postmortem brain of suicide victims and patients with bipolar disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Increased G alpha q/11 immunoreactivity in postmortem occipital cortex from patients with bipolar affective disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Imipramine-induced changes in 5-HT2 receptor sites and inositoltrisphosphate levels in rat brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Reduced Brain Inositol in Lithium-treated Rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Neural and developmental actions of lithium: a unifying hypothesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium and brain signal transduction systems

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Ziskind-Somerfeld Research Award 1993. Biochemical, behavioral, and clinical studies of the role of inositol in lithium treatment and depression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Potentiation by lithium of CMP-phosphatidate formation in carbachol-stimulated rat cerebral-cortical slices and its reversal by myo-inositol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Evidence that a proconvulsant action of lithium is mediated by inhibition of myo-inositol phosphatase in mouse brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The mechanism of protein kinase C activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium inhibition of protein kinase C activation-induced serotonin release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The role of protein kinase C and its neuronal substrates dephosphin, B-50, and MARCKS in neurotransmitter release

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic lithium administration alters a prominent PKC substrate in rat hippocampus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium decreases membrane-associated protein kinase C in hippocampus: selectivity for the alpha isozyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Selective Inhibition of the Expression of Signal Transduction Proteins by Lithium in Nerve Growth Factor‐Differentiated PC12 Cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Chronic sodium valproate selectively decreases protein kinase C alpha and epsilon in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Valproate robustly enhances AP-1 mediated gene expression

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium stimulates gene expression through the AP-1 transcription factor pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Lithium increases tyrosine hydroxylase levels both in vivo and in vitro.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

A new intellectual framework for psychiatry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Neuropathology of bipolar disorder

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

Clinical and preclinical evidence for the neurotrophic effects of mood stabilizers: implications for the pathophysiology and treatment of manic-depressive illness

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

The mood-stabilizing agent valproate inhibits the activity of glycogen synthase kinase-3.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-3999%2802%2900426-9

10.1016/S0022-3999(02)00426-9

7 January 2021

Identifiers

DOI

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release_osifvxz7prg53nfg2766ulmqoq

4 August 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/osifvxz7prg53nfg2766ulmqoq

mapped directly with Wikidata item

24 November 2022

based on heuristic

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