Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation (Q34747296)

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English	Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation	scientific article

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scholarly article

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Europe PubMed Central

PubMed publication ID

4 August 2017

Rapamycin protection of livers from ischemia and reperfusion injury is dependent on both autophagy induction and mammalian target of rapamycin complex 2-Akt activation (English)

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Europe PubMed Central

PubMed publication ID

4 August 2017

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reperfusion injury

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based on heuristic

inferred from title

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based on heuristic

inferred from title

Jerzy Kupiec-Węgliński

7

object named as

Jerzy W Kupiec-Weglinski

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Europe PubMed Central

PubMed publication ID

4 August 2017

5

object named as

Feng Gao

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PubMed publication ID

4 August 2017

author name string

Jianjun Zhu

1

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Europe PubMed Central

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4 August 2017

Tianfei Lu

2

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4 August 2017

Shi Yue

3

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Europe PubMed Central

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4 August 2017

Xiuda Shen

4

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Europe PubMed Central

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4 August 2017

Ronald W Busuttil

6

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4 August 2017

Qiang Xia

8

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4 August 2017

Yuan Zhai

9

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4 August 2017

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publication date

1 January 2015

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Europe PubMed Central

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4 August 2017

Transplantation

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4 August 2017

99

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Europe PubMed Central

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4 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

48-55

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Europe PubMed Central

PubMed publication ID

4 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4272660/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Mechanistic target of rapamycin complex 2 protects the heart from ischemic damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Liver transplantation: an appraisal of the present situation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy as a stress-response and quality-control mechanism: implications for cell injury and human disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Rapamycin protects against myocardial ischemia-reperfusion injury through JAK2-STAT3 signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy in proximal tubules protects against acute kidney injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

PTEN-mediated Akt/β-catenin/Foxo1 signaling regulates innate immune responses in mouse liver ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

mTOR signaling in growth control and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy as a therapeutic target for ischaemia /reperfusion injury? Concepts, controversies, and challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

AMPK and mTOR in cellular energy homeostasis and drug targets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Activation of autophagy protects against acetaminophen-induced hepatotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

The functions of mTOR in ischemic diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy suppresses age-dependent ischemia and reperfusion injury in livers of mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

m-TOR inhibitors: what role in liver transplantation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy and the Integrated Stress Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

AKT signaling in physiology and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy during cardiac stress: joys and frustrations of autophagy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

The multifunctional role of mTOR in innate immunity: implications for transplant immunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Impaired autophagy: A mechanism of mitochondrial dysfunction in anoxic rat hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Enhancing macroautophagy protects against ischemia/reperfusion injury in cardiac myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Autophagy in chronically ischemic myocardium.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

7 July 2018

Rapamycin attenuates mitochondrial dysfunction via activation of mitophagy in experimental ischemic stroke.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Melatonin inhibits mTOR-dependent autophagy during liver ischemia/reperfusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Dual role of chloroquine in liver ischemia reperfusion injury: reduction of liver damage in early phase, but aggravation in late phase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Differential roles of GSK-3β during myocardial ischemia and ischemia/reperfusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Rapamycin inhibits cholangiocyte regeneration by blocking interleukin-6-induced activation of signal transducer and activator of transcription 3 after liver transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Mammalian target of rapamycin (mTOR) orchestrates the defense program of innate immune cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

The TSC-mTOR signaling pathway regulates the innate inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

CXCL10 regulates liver innate immune response against ischemia and reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Distinct roles of autophagy in the heart during ischemia and reperfusion: roles of AMP-activated protein kinase and Beclin 1 in mediating autophagy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Ischemic postconditioning protects remodeled myocardium via the PI3K-PKB/Akt reperfusion injury salvage kinase pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

CD154-CD40 T-cell costimulation pathway is required in the mechanism of hepatic ischemia/reperfusion injury, and its blockade facilitates and depends on heme oxygenase-1 mediated cytoprotection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

At the core of survival: Autophagy delays the onset of both apoptotic and necrotic cell death in a model of ischemic cell injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

26 October 2018

Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4272660

9 December 2018

Autophagy in myocardium of murine hearts subjected to ischemia followed by reperfusion

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophil infiltration as an important factor in liver ischemia and reperfusion injury. Modulating effects of FK506 and cyclosporine

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Beneficial effects of cyclosporine and rapamycin in small bowel ischemic injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunosuppressants decrease neutrophil chemoattractant and attenuate ischemia/reperfusion injury of the liver in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of rapamycin on renal ischemia-reperfusion injury in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of heme oxygenase 1 in rapamycin-induced renal dysfunction after ischemia and reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sirolimus improves early microcirculation, but impairs regeneration after pancreatic ischemia-reperfusion injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/25340604

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/TP.0000000000000476

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

4 August 2017

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