The effective opening of nicotinic acetylcholine receptors with single agonist binding sites (Q34745010)

4 August 2017

title

The effective opening of nicotinic acetylcholine receptors with single agonist binding sites (English)

1 reference

4 August 2017

Dustin K Williams

1 reference

4 August 2017

Clare Stokes

series ordinal

1 reference

4 August 2017

Nicole A Horenstein

series ordinal

1 reference

4 August 2017

Roger L Papke

series ordinal

1 reference

4 August 2017

publication date

1 April 2011

1 reference

The Journal of General Physiology

4 August 2017

published in

1 reference

4 August 2017

volume

137

1 reference

4 August 2017

1 reference

4 August 2017

page(s)

369-384

1 reference

Tethered Agonist Analogs as Site-Specific Probes for Domains of the Human α7 Nicotinic Acetylcholine Receptor that Differentially Regulate Activation and Desensitization

4 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Cysteine accessibility analysis of the human alpha7 nicotinic acetylcholine receptor ligand-binding domain identifies L119 as a gatekeeper

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Acetylcholine receptor channels activated by a single agonist molecule

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Number and locations of agonist binding sites required to activate homomeric Cys-loop receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Single-channel recording of ligand-gated ion channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

The alpha7 nicotinic acetylcholine receptor as a pharmacological target for inflammation.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Nicotinic acetylcholine receptors and nicotinic cholinergic mechanisms of the central nervous system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

The activation mechanism of alpha1 homomeric glycine receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

The nicotinic receptor ligand binding domain

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Comparative pharmacology of rat and human alpha7 nAChR conducted with net charge analysis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Open probability of homomeric murine 5-HT3A serotonin receptors depends on subunit occupancy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Crystal structure of an ACh-binding protein reveals the ligand-binding domain of nicotinic receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

SWISS‐MODEL and the Swiss‐Pdb Viewer: An environment for comparative protein modeling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Diffuse transmission by acetylcholine in the CNS

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Identification of Equivalent Residues in the γ, δ, and ε Subunits of the Nicotinic Receptor That Contribute to α-Bungarotoxin Binding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Insights into the activation mechanism of rho1 GABA receptors obtained by coexpression of wild type and activation-impaired subunits.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

alpha-Conotoxins selectively inhibit one of the two acetylcholine binding sites of nicotinic receptors.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Molecular structure of the nicotinic acetylcholine receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Agonists block currents through acetylcholine receptor channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Spontaneous openings of the acetylcholine receptor channel

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Activation of a nicotinic acetylcholine receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Fluctuations in the microsecond time range of the current through single acetylcholine receptor ion channels

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

The Affinity-Labeling of Partially Purified Acetylcholine Receptor from Electric Tissue of Electrophorus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Mechanisms of noncompetitive inhibition of acetylcholine-induced single-channel currents

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Relationships of agonist properties to the single channel kinetics of nicotinic acetylcholine receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by high concentrations of agonist.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Developmental regulation of nicotinic acetylcholine receptors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Activation of acetylcholine receptors on clonal mammalian BC3H-1 cells by low concentrations of agonist.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Kinetics of unliganded acetylcholine receptor channel gating

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Fast events in single-channel currents activated by acetylcholine and its analogues at the frog muscle end-plate

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Time-dependent changes in cerebral choline and acetylcholine induced by transient global ischemia in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Seizures increase acetylcholine and choline concentrations in rat brain regions

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Reversal of agonist selectivity by mutations of conserved amino acids in the binding site of nicotinic acetylcholine receptors

7 July 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Characterization of the neuroprotective and toxic effects of alpha7 nicotinic receptor activation in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

The correction of alpha7 nicotinic acetylcholine receptor concentration-response relationships in Xenopus oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

alpha7 receptor-selective agonists and modes of alpha7 receptor activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Role of acetylcholine receptor subunits in gating of the channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

The structural basis for GTS-21 selectivity between human and rat nicotinic alpha7 receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Activation and inhibition of native neuronal alpha-bungarotoxin-sensitive nicotinic ACh receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Regulation of neuronal function by choline and 4OH-GTS-21 through alpha 7 nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Neuronal nicotinic alpha 7 receptor expressed in Xenopus oocytes presents five putative binding sites for methyllycaconitine

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Kinetic differences between embryonic- and adult-type acetylcholine receptors in rat myotubes.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

The occurrence of long openings in the purified cholinergic receptor channel increases with acetylcholine concentration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3068282

Acetylcholine receptors: too many channels, too few functions

26 October 2018

1 reference

https://api.crossref.org/works/10.1085%2FJGP.201010587

Liquid filament switch for ultra-fast exchanges of solutions at excised patches of synaptic membrane of crayfish muscle

21 January 2018

1 reference

12 December 2020

A study of the desensitization produced by acetylcholine at the motor end-plate

1 reference

12 December 2020

The relationship between agonist occupation and the permeability response of the cholinergic receptor revealed by bound cobra alpha-toxin

1 reference

12 December 2020

A patch-clamp study of the partial agonist actions of tubocurarine on rat myotubes

1 reference

12 December 2020

Identifiers

DOI

10.1085/JGP.201010587

1 reference

release_6u2oj2bndvftpfegieercet2ga

4 August 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/6u2oj2bndvftpfegieercet2ga

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3068282

1 reference

4 August 2017

1 reference